The cardiovascular consequences of electronic cigarette smoking: a narrative review

P. Fountoulakis,P. Theofilis,S. Tsalamandris,A. Antonopoulos,P. Tsioufis,Konstantinos Toutouzas,E. Oikonomou,K. Tsioufis,D. Tousoulis

Published 2023 in Expert Review of Cardiovascular Therapy

ABSTRACT

ABSTRACT Introduction E-cigarettes have emerged as a popular alternative to traditional tobacco smoking in recent years. Despite their growing popularity, concerns have arisen regarding the cardiovascular implications of e-cigarette use. Areas covered This narrative review aims to highlight the latest evidence on the impact of e-cigarettes on cardiovascular health. Expert opinion Numerous studies have demonstrated that e-cigarette use can lead to acute adverse cardiovascular effects. Inhalation of e-cigarette aerosols exposes users to a wide range of potentially harmful substances that have been implicated in critical pathophysiologic pathways of cardiovascular disease, namely endothelial dysfunction, oxidative stress, inflammation, sympathetic overdrive, and arterial stiffness. While long-term epidemiological studies specifically focusing on the cardiovascular effects of e-cigarettes are still relatively scarce, early evidence suggests a potential association between e-cigarette use and an increased risk of adverse cardiovascular events. However, it is essential to recognize that e-cigarettes are relatively new products, and the full extent of their long-term cardiovascular impact has not been fully elucidated. In the meantime, promoting tobacco cessation strategies that are evidence-based and regulated, along with rigorous monitoring of e-cigarette use patterns and associated health outcomes, are essential steps in safeguarding cardiovascular health in the face of this emerging public health challenge.

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