Pancreatic duct pressure: A review of technical aspects and clinical significance.

Anmol Singh,Nikhil Bush,Furqan A. Bhullar,M. Faghih,C. Moreau,Rajat Mittal,J. Seo,R. Talukdar,S. Lakhtakia,Vikesh K. Singh,V. Akshintala

Published 2023 in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]

ABSTRACT

Pancreatic duct pressure (PDP) dynamics comprise an intricately modulated system that helps maintain homeostasis of pancreatic function. It is affected by various factors, including the rate of pancreatic fluid secretion, patency of the ductal system, sphincter of Oddi function, and pancreatic fluid characteristics. Disease states such as acute and chronic pancreatitis can alter the normal PDP dynamics. Ductal hypertension or increased PDP is suspected to be involved in the pathogenesis of pancreatic pain, endocrine and exocrine pancreatic insufficiency, and recurrent pancreatitis. This review provides a comprehensive appraisal of the available literature on PDP, including the methods used in the measurement and clinical implications of elevated PDP.

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