Physiological concentrations of 17beta-estradiol inhibit the synthesis of nitric oxide synthase in macrophages via a receptor-mediated system.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Cardiovascular Pharmacology

• Publication date

  1998-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00005344-199802000-00016PMID 9475272
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence.

  2004cited by this paper
• Simultaneous Measurement of Nitrite and Nitrate Levels as Indices of Nitric Oxide Release in the Cerebellum of Conscious Rats

  1997cited by this paper
• Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.

  1997cited by this paper
• Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors a and b

  1997cited by this paper
• Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits.

  1997cited by this paper
• ER beta: identification and characterization of a novel human estrogen receptor.

  1996cited by this paper
• ERβ: Identification and characterization of a novel human estrogen receptor

  1996cited by this paper
• Cloning of a novel receptor expressed in rat prostate and ovary.

  1996cited by this paper
• Gender Differences in Atherosclerosis: Possible Role of Nitric Oxide

  1995cited by this paper
• Estrogen increases endothelial nitric oxide by a receptor-mediated system.

  1995cited by this paper
• Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene.

  1995cited by this paper
• Up‐regulation of nitric oxide synthase by estradiol in human aorticendothelial cells

  1995cited by this paper
• Estrogen modulation of JE/monocyte chemoattractant protein-1 mRNA expression in murine macrophages.

  1995cited by this paper
• Inhibition of NF-kappa B by sodium salicylate and aspirin.

  1994cited by this paper
• Nitric oxide accounts for dose-dependent estrogen-mediated coronary relaxation after acute estrogen withdrawal.

  1994cited by this paper
• Practical nitric oxide measurement employing a nitric oxide‐selective electrode

  1994cited by this paper
• Organization of the bovine gene encoding the endothelial nitric oxide synthase.

  1994cited by this paper
• An energy dispersive x‐ray absorption spectroscopy beamline, X6A, at NSLS

  1994cited by this paper
• Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The Atherosclerosis Risk in Communities Study Investigators.

  1993cited by this paper
• Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.

  1993cited by this paper
• Cardiovascular protection by oestrogen--a calcium antagonist effect?

  1993cited by this paper
• Association of Hormone-Replacement Therapy With Various Cardiovascular Risk Factors in Postmenopausal Women

  1993cited by this paper
• Nitric oxide release from a single cell measured in situ by a porphyrinic-based microsensor

  1992cited by this paper
• Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.

  1992cited by this paper
• Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

  1992cited by this paper
• Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidence☆☆☆

  1991cited by this paper
• Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro.

  1991cited by this paper
• Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins.

  1991cited by this paper
• Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

  1990cited by this paper
• Estrogen modulates responses of atherosclerotic coronary arteries.

  1990cited by this paper
• Nitric oxide: a cytotoxic activated macrophage effector molecule.

  1988cited by this paper
• Postmenopausal use of estrogen and occlusion of coronary arteries.

  1988cited by this paper
• The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

  1987cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• 17β-estradiol inhibits Notch1 activation in murine macrophage cell line RAW 264.7

  2024cites this paper
• Transcriptomic and epigenomic effects of insoluble particles on J774 macrophages

  2020cites this paper
• Protective role of natural products in glioblastoma multiforme: A focus on nitric oxide pathway.

  2020cites this paper
• Hormonal Expression Associated with Alzheimer's Disease and Neurodegenerative Diseases

  2019cites this paper
• The effect of talc particles on phagocytes in co-culture with ovarian cancer cells.

  2019cites this paper
• cellular, biochemical, and molecular mechanisms Estrogen-induced cardiorenal protection: potential

  2016cites this paper
• An Estrogen Receptor Dependent Mechanism of Oroxylin A in the Repression of Inflammatory Response

  2013cites this paper
• The influence of aging and estradiol to progesterone ratio on rat macrophage phenotypic profile and NO and TNF-α production.

  2013cites this paper
• Estradiol reduces depressive-like behavior through inhibiting nitric oxide/cyclic GMP pathway in ovariectomized mice.

  2013cites this paper
• In Vitro and In Vivo Evidence for Anti-Inflammatory Properties of 2-Methoxyestradiol

  2011cites this paper
• Inducible nitric oxide synthase inhibitor aminoguanidine, differently affects Morris water maze tasks of ovariectomized and naïve female rats.

  2011cites this paper
• UNIVERSIDADE ESTADUAL DE PONTA GROSSA PROGRAMA DE PÓS-GRADUAÇÃO EM BIOLOGIA EVOLUTIVA (Associação Ampla entre a UEPG e a UNICENTRO) EFEITO DA GENISTEÍNA NA FUNCIONALIDADE DE MACRÓFAGOS: UM ESTUDO COMPARATIVO ENTRE RATOS MACHOS E FÊMEAS

  2011cites this paper
• Phenolic compounds from plants as nitric oxide production inhibitors.

  2011cites this paper
• Modulation of immune functions by oestrogens. Part II Immunomodulacyjna rola estrogenów. Czêœæ II

  2010cites this paper
• Gender Issues in Host Defense

  2010cites this paper
• Immunomodulacyjna rola estrogenów. Czêœæ I

  2010cites this paper
• up-regulation of occludin and junctional adhesion molecule-A in epithelial cells Oestradiol decreases colonic permeability through oestrogen receptor \#946;-mediated

  2009cites this paper
• Estrogen Regulates Transcription Factors STAT-1 and NF-κB to Promote Inducible Nitric Oxide Synthase and Inflammatory Responses1

  2009cites this paper
• The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage.

  2007cites this paper
• The complex role of estrogens in inflammation.

  2007cites this paper
• Redox Features of the Cell: A Gender Perspective

  2007cites this paper
• MULTIPLE SCLEROSIS : PSYCHOSOMATIC ORIGINS AND THE ROLE OF NITRIC OXIDE

  2007cites this paper
• Potential role of female sex hormones in the pathophysiology of migraine.

  2007cites this paper
• Resveratrol Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation via Estrogen Receptor Dependent Nitric Oxide Production

  2007cites this paper
• Estrogen as a new therapeutic target for asthma and chronic obstructive pulmonary disease.

  2007cites this paper
• High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis.

  2007cites this paper
• Effects of estrogen against LPS-induced inflammation and toxicity in primary rat glial and neuronal cultures

  2007cites this paper
• Abbreviated title: Estrogen and brain inflammation

  2006cites this paper
• Female's heightened immune status: estrogen, T cells, and inducible nitric oxide synthase in the balance.

  2006cites this paper
• The endogenous estrogen status regulates microglia reactivity in animal models of neuroinflammation.

  2006cites this paper
• Vascular Pharmacology of Migraine and Preeclampsia: Problems of the Fair Sex

  2006cites this paper
• Reproductive Hormones Modulate Oxidative Stress in Alzheimer's Disease

  2006cites this paper
• Modulatory effects of progesterone on inducible nitric oxide synthase expression in vivo and in vitro

  2005influential citation
• 17β-Estradiol Inhibits Inflammatory Gene Expression by Controlling NF-κB Intracellular Localization

  2005cites this paper
• Vascular Pharmacology of Migraine and Preeclampsia

  2005cites this paper
• Ovariectomy alters the structural and biomechanical properties of ovine femoro-tibial articular cartilage and increases cartilage iNOS.

  2005cites this paper
• Sex differences and the effect of hormonal therapy on ischemic brain injury.

  2005cites this paper
• Gender and estrogen supplementation increases severity of experimental choroidal neovascularization.

  2005cites this paper
• 17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization.

  2005cites this paper
• Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase.

  2005cites this paper
• Ovariectomy enhances renal cortical expression and function of cyclooxygenase-2.

  2004cites this paper
• MECHANISM OF SALUTARY EFFECTS OF ANDROSTENEDIOL ON HEPATIC FUNCTION FOLLOWING TRAUMA-HEMORRHAGE : THE ROLE OF ENDOTHELIAL AND INDUCIBLE NITRIC OXIDE SYNTHASE

  2004cites this paper
• Gender‐Specific Regulation of Cardiovascular Function: Estrogen as Key Player

  2004cites this paper
• Regulation of the lipopolysaccharide signal transduction pathway by 17beta-estradiol in macrophage cells.

  2004cites this paper
• STUDIO DEL MECCANISMO D'AZIONE DEL 17 β-ESTRADIOLO SULL'ATTIVAZIONE DI NF- κB

  2004cites this paper
• Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells.

  2004cites this paper
• Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor beta.

  2004cites this paper
• 17 beta-estradiol increases inducible nitric oxide synthase expression in macrophages.

  2003cites this paper
• Lower skeletal muscle nutritive blood flow in older women is related to eNOS protein content.

  2003cites this paper
• 17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells.

  2003cites this paper
• INFLUENCE OF STEROIDS ON OXIDANT GENERATION IN ACTIVATED HUMAN GRANULOCYTES AND MONONUCLEAR LEUKOCYTES

  2003cites this paper
• Concomitant production of nitric oxide and superoxide in human macrophages.

  2003cites this paper
• Xenoestrogens: do they lower survival after thermal injury?

  2003cites this paper
• 17beta-estradiol- and lipopolysaccharide-induced changes in nitric oxide, tumor necrosis factor-alpha and vascular endothelial growth factor release from RAW 264.7 macrophages.

  2003cites this paper
• An Inducible Nitric Oxide Synthase-Luciferase Reporter System for In Vivo Testing of Anti-inflammatory Compounds in Transgenic Mice1

  2003cites this paper
• 17β-Estradiol- and Lipopolysaccharide-Induced Changes in Nitric Oxide, Tumor Necrosis Factor-α and Vascular Endothelial Growth Factor Release from RAW 264.7 Macrophages

  2003cites this paper
• 17β-Estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells

  2003cites this paper
• Down-regulation of inducible nitric oxide synthase and tumor necrosis factor-alpha expression by bisphenol A via nuclear factor-kappaB inactivation in macrophages.

  2003cites this paper
• Compounds in Transgenic Mice Vivo Testing of Anti-inflammatory Synthase-Luciferase Reporter System for In An Inducible Nitric Oxide

  2003cites this paper
• Suppression of inducible nitric oxide synthase and tumor necrosis factor-alpha expression by 4-nonylphenol in macrophages.

  2002cites this paper
• Beta Amyloid Protein Clearance and Microglial Activation

  2002cites this paper
• Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action.

  2002cites this paper
• Modulatory effects of estrogen in two murine models of experimental colitis.

  2002cites this paper
• Changes in proinflammatory cytokine activity after menopause.

  2002cites this paper
• Direct effects of estrogen on the vessel wall

  2001cites this paper
• Selected contribution: Effects of gender on reduced-size liver ischemia and reperfusion injury.

  2001cites this paper
• Cytokine and nitric oxide release by J774A.1 macrophages is not regulated by estradiol.

  2001cites this paper
• review Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms

  2001cites this paper
• Alcoholic liver disease: a matter of hormones?

  2001cites this paper
• Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms.

  2001cites this paper
• Pro: Postmenopausal hormone replacement therapy improves outcome in women undergoing coronary artery bypass graft surgery.

  2001cites this paper
• Estrogen-Induced Vasoprotection Is Independent of Inducible Nitric Oxide Synthase Expression: Evidence From the Mouse Carotid Artery Ligation Model

  2001cites this paper
• Estrogen (E2) and glucocorticoid (Gc) effects on microglia and A beta clearance in vitro and in vivo.

  2001cites this paper
• Estrogen Prevents the Lipopolysaccharide-Induced Inflammatory Response in Microglia

  2001cites this paper
• 17beta-estradiol antiinflammatory activity in carrageenan-induced pleurisy.

  2000cites this paper
• 17 b -Estradiol corrects hemostasis in uremic rats by limiting vascular expression of nitric oxide synthases

  2000cites this paper
• Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas.

  2000cites this paper
• Inhibition of inducible nitric oxide synthase gene expression by indomethacin or ibuprofen in beta-amyloid protein-stimulated J774 cells.

  2000cites this paper
• Stroke Outcome in Double-Mutant Antioxidant Transgenic Mice

  2000cites this paper
• 17β-Estradiol corrects hemostasis in uremic rats by limiting vascular expression of nitric oxide synthases

  2000cites this paper
• eNOS expression is associated with the estrogen and progesterone receptor status in invasive breast carcinoma.

  2000cites this paper
• Female Sex Hormones Modulate the Function of LPS‐treated Macrophages

  2000cites this paper
• Role of Nitric Oxide in the Antiatherosclerotic Effect of 17β-Estradiol

  2000cites this paper
• EFFECT OF GENDER AND SEX HORMONES ON IMMUNE RESPONSES FOLLOWING SHOCK

  2000cites this paper
• 17β-Estradiol Antiinflammatory Activity in Carrageenan-Induced Pleurisy.

  2000cites this paper
• Production of nitric oxide by glial cells: Regulation and potential roles in the CNS

  2000cites this paper
• Biology of Menopause

  2000cites this paper
• 17beta-estradiol corrects hemostasis in uremic rats by limiting vascular expression of nitric oxide synthases.

  2000cites this paper
• Female sex steroids: effects upon microglial cell activation.

  2000cites this paper
• Interleukin-1beta-induced nitric oxide production in rat aortic endothelial cells: inhibition by estradiol in normal and high glucose cultures.

  1999cites this paper
• Beta-estradiol-induced decrease in IL-12 and TNF-alpha expression suppresses macrophage functions in the course of Listeria monocytogenes infection in mice.

  1999cites this paper
• Effects of estrogen on nitric oxide synthase expression in rat aorta allograft and smooth muscle cells.

  1999cites this paper
• Oestrogenic Compounds Modulate Cytokine‐induced Nitric Oxide Production in Mouse Osteoblast‐like Cells

  1999cites this paper
• 17β-Estradiol Decreases Nitric Oxide Synthase II Synthesis in Vascular Smooth Muscle Cells.

  1999cites this paper
• Estrogen, natriuretic peptides and the renin–angiotensin system

  1999cites this paper
• Idoxifene, a novel selective estrogen receptor modulator, is effective in a rat model of adjuvant-induced arthritis.

  1999cites this paper
• Estrogen and progesterone induction of survival of monoblastoid cells undergoing TNF‐α‐induced apoptosis

  1999cites this paper
• 17 b -Estradiol Decreases Nitric Oxide Synthase II Synthesis in Vascular Smooth Muscle Cells*

  1999cites this paper
• Postmenopausal hormone replacement therapy and the vascular wall: mechanisms of 17 beta-estradiol's effects on vascular biology.

  1999cites this paper
• Estrogen and nitric oxide in vasculature

  1999cites this paper