miR-20b-5p exerts protective effects against experimental autoimmune encephalomyelitis in mice by inhibiting NLRP3 transcription and NLRP3/ASC/caspase-1 axis activation

No abstract is available for this paper.

• Publication year

  2023

• Venue

  Molecular & Cellular Toxicology

• Publication date

  2023-10-13

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1007/s13273-023-00398-3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  2014influential reference
• Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b

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  2014cited by this paper
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  2014cited by this paper
• The role of miRNA in inflammation and autoimmunity.

  2013cited by this paper
• Role of microRNAs in central nervous system development and pathology

  2012cited by this paper
• Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

  2011cited by this paper
• T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

  2010cited by this paper
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  2010cited by this paper
• Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis.

  2010cited by this paper
• MicroRNAs: new regulators of immune cell development and function

  2008cited by this paper
• An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization

  2005cited by this paper
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  2003cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• Guide for the Care and Use of Laboratory Animals

  1996cited by this paper

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  2025cites this paper