Post-Translational Modifications in Histones and Their Role in Abiotic Stress Tolerance in Plants

Abiotic stresses profoundly alter plant growth and development, resulting in yield losses. Plants have evolved adaptive mechanisms to combat these challenges, triggering intricate molecular responses to maintain tissue hydration and temperature stability during stress. A pivotal player in this defense is histone modification, governing gene expression in response to diverse environmental cues. Post-translational modifications (PTMs) of histone tails, including acetylation, phosphorylation, methylation, ubiquitination, and sumoylation, regulate transcription, DNA processes, and stress-related traits. This review comprehensively explores the world of PTMs of histones in plants and their vital role in imparting various abiotic stress tolerance in plants. Techniques, like chromatin immune precipitation (ChIP), ChIP-qPCR, mass spectrometry, and Cleavage Under Targets and Tag mentation, have unveiled the dynamic histone modification landscape within plant cells. The significance of PTMs in enhancing the plants’ ability to cope with abiotic stresses has also been discussed. Recent advances in PTM research shed light on the molecular basis of stress tolerance in plants. Understanding the intricate proteome complexity due to various proteoforms/protein variants is a challenging task, but emerging single-cell resolution techniques may help to address such challenges. The review provides the future prospects aimed at harnessing the full potential of PTMs for improved plant responses under changing climate change.

• Publication year

  2023

• Venue

  Proteomes

• Publication date

  2023-11-22

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.3390/proteomes11040038PMID 38133152PMCID 10747722
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biotinylated Tn5 transposase‐mediated CUT&Tag efficiently profiles transcription factor‐DNA interactions in plants

  2023cited by this paper
• From challenges to solutions: The impact of melatonin on abiotic stress synergies in horticultural plants via redox regulation and epigenetic signaling

  2023cited by this paper
• Time-Series Transcriptomic Analysis of Contrasting Rice Materials under Heat Stress Reveals a Faster Response in the Tolerant Cultivar

  2023cited by this paper
• Multiple Abiotic Stress Tolerances in Higher Plants

  2023cited by this paper
• Transcriptional and Metabolic Profiling of Arabidopsis thaliana Transgenic Plants Expressing Histone Acetyltransferase HAC1 upon the Application of Abiotic Stress—Salt and Low Temperature

  2023cited by this paper
• Neglected PTM in Animal Adipogenesis: E3-mediated Ubiquitination.

  2023cited by this paper
• The diverse roles of histone 2b monoubiquitination in the life of plants.

  2022cited by this paper
• An Epigenetic Alphabet of Crop Adaptation to Climate Change

  2022cited by this paper
• Polycomb Repressive Complex 2 in Eukaryotes—An Evolutionary Perspective

  2022cited by this paper
• Chromatin-Based Transcriptional Reprogramming in Plants under Abiotic Stresses

  2022cited by this paper
• HD2A and HD2C co-regulate drought stress response by modulating stomatal closure and root growth in Arabidopsis

  2022cited by this paper
• Histone modification and chromatin remodeling in plant response to pathogens

  2022cited by this paper
• ICE-CBF-COR Signaling Cascade and Its Regulation in Plants Responding to Cold Stress

  2022cited by this paper
• Dynamic regulation of DNA methylation and histone modifications in response to abiotic stresses in plants.

  2022cited by this paper
• Histone acetyltransferase TaHAG1 interacts with TaNACL to promote heat stress tolerance in wheat

  2022cited by this paper
• Uncovering the Epigenetic Marks Involved in Mediating Salt Stress Tolerance in Plants

  2022cited by this paper
• RING Zinc Finger Proteins in Plant Abiotic Stress Tolerance

  2022cited by this paper
• Histone ubiquitination controls organ size in cotton (Gossypium hirsutum).

  2022cited by this paper
• Histone Mono-Ubiquitination in Transcriptional Regulation and Its Mark on Life: Emerging Roles in Tissue Development and Disease

  2022cited by this paper
• Epigenetic regulation of heat and cold stress responses in crop plants

  2022cited by this paper
• OUP accepted manuscript

  2022cited by this paper
• Functional characterization of wheat histone H2B monoubiquitination enzyme TaHUB2 in response to vernalization in Keumkang (Triticum aestivum L.)

  2021cited by this paper
• Histone Modifications and Chromatin Remodelling in Plants in Response to Salt Stress.

  2021cited by this paper
• Functional analysis of tomato CHIP ubiquitin E3 ligase in heat tolerance

  2021cited by this paper
• In Response to Abiotic Stress, DNA Methylation Confers EpiGenetic Changes in Plants

  2021cited by this paper
• Single-cell profiling of transcriptome and histone modifications with EpiDamID

  2021cited by this paper
• Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression

  2021cited by this paper
• Histone acetyltransferase TaHAG1 acts as a crucial regulator to strengthen salt tolerance of hexaploid wheat

  2021cited by this paper
• Phosphorylation of Histone H2A at Serine 95 Is Essential for Flowering Time and Development in Arabidopsis

  2021cited by this paper
• Progressive Genomic Approaches to Explore Drought- and Salt-Induced Oxidative Stress Responses in Plants under Changing Climate

  2021cited by this paper
• Post-translational modifications in proteins: resources, tools and prediction methods

  2021cited by this paper
• Coping with low moisture stress: remembering and responding.

  2021cited by this paper
• Plants’ Epigenetic Mechanisms and Abiotic Stress

  2021cited by this paper
• Function of histone H2B monoubiquitination in transcriptional regulation of auxin biosynthesis in Arabidopsis

  2021cited by this paper
• Understanding the roles of osmolytes for acclimatizing plants to changing environment: a review of potential mechanism

  2021cited by this paper
• Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues

  2021cited by this paper
• The protein modifier SUMO is critical for integrity of the Arabidopsis shoot apex at warm ambient temperatures.

  2021cited by this paper
• Multifaceted Chromatin Structure and Transcription Changes in Plant Stress Response

  2021cited by this paper
• Histone Acetylation Changes in Plant Response to Drought Stress

  2021cited by this paper
• A novel method for the normalization of ChIP-qPCR data

  2021cited by this paper
• The Dynamism of Transposon Methylation for Plant Development and Stress Adaptation

  2021cited by this paper
• Metabolic control of histone demethylase activity involved in plant response to high temperature.

  2021cited by this paper
• SUMO mediated regulation of transcription factors as a mechanism for transducing environmental cues into cellular signaling in plants

  2021cited by this paper
• Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants

  2021cited by this paper
• Updated Mechanisms of GCN5—The Monkey King of the Plant Kingdom in Plant Development and Resistance to Abiotic Stresses

  2021cited by this paper
• Proteasomal Degradation of Proteins Is Important for the Proper Transcriptional Response to Sulfur Deficiency Conditions in Plants

  2020cited by this paper
• SUMO and SUMOylation in plant abiotic stress

  2020cited by this paper
• Top-Down Mass Spectrometry of Histone Modifications in Sorghum Reveals Potential Epigenetic Markers for Drought Acclimation.

  2020cited by this paper
• The Ubiquitin E3 Ligase MaLUL2 Is Involved in High Temperature-Induced Green Ripening in Banana Fruit

  2020cited by this paper
• Brassinosteroids in Plant Tolerance to Abiotic Stress

  2020cited by this paper
• Chromatin Immunoprecipitation (ChIP) to Assess Histone Marks in Auxin-treated Arabidopsis thaliana Inflorescence Tissue.

  2020cited by this paper
• Methods for ChIP-seq analysis: A practical workflow and advanced applications.

  2020cited by this paper
• Oryza sativa drought-, heat-, and salt-induced RING finger protein 1 (OsDHSRP1) negatively regulates abiotic stress-responsive gene expression

  2020cited by this paper
• Genetically modified crops: current status and future prospects

  2020cited by this paper
• The Chromatin Response to Double-Strand DNA Breaks and Their Repair

  2020cited by this paper
• Characterizing the Role of the miR156-SPL Network in Plant Development and Stress Response

  2020cited by this paper
• Understanding epigenetic modifications in response to abiotic stresses in plants

  2020cited by this paper
• Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses

  2020cited by this paper
• Engineering Multiple Abiotic Stress Tolerance in Canola, Brassica napus

  2020cited by this paper
• A novel role of salt and drought induced RING 1 protein in modulating plant defense against hemibiotrophic and necrotrophic pathogens.

  2020cited by this paper
• Efficient chromatin profiling of H3K4me3 modification in cotton using CUT&Tag

  2020cited by this paper
• Salinity stress induces epigenetic alterations to the promoter of MsMYB4 encoding a salt-induced MYB transcription factor.

  2020cited by this paper
• Overexpression of GmUBC9 Gene Enhances Plant Drought Resistance and Affects Flowering Time via Histone H2B Monoubiquitination

  2020cited by this paper
• Editorial: New Insights Into Mechanisms of Epigenetic Modifiers in Plant Growth and Development

  2020cited by this paper
• Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature

  2020cited by this paper
• COST1 regulates autophagy to control plant drought tolerance

  2020cited by this paper
• Plant Epigenetic Stress Memory Induced by Drought: A Physiological and Molecular Perspective.

  2020cited by this paper
• Histone deacetylase HDA710 controls salt tolerance by regulating ABA signaling in rice.

  2020cited by this paper
• Efficient low-cost chromatin profiling with CUT&Tag

  2020cited by this paper
• Histone Deacetylase HDA9 With ABI4 Contributes to Abscisic Acid Homeostasis in Drought Stress Response

  2020cited by this paper
• Histone tales: lysine methylation, a protagonist in Arabidopsis development.

  2019cited by this paper
• Dynamic changes in histone modification are associated with upregulation of Hsf and rRNA genes during heat stress in maize seedlings

  2019cited by this paper
• A U-box E3 ubiquitin ligase OsPUB67 is positively involved in drought tolerance in rice

  2019cited by this paper
• Transcription-driven chromatin repression of Intragenic transcription start sites

  2019cited by this paper
• ROS1-Dependent DNA Demethylation Is Required for ABA-Inducible NIC3 Expression1[OPEN]

  2019cited by this paper
• Ethylene Response Factor (ERF) Family Proteins in Abiotic Stresses and CRISPR–Cas9 Genome Editing of ERFs for Multiple Abiotic Stress Tolerance in Crop Plants: A Review

  2019cited by this paper
• Reversible Histone H2B Monoubiquitination Fine-Tunes Abscisic Acid Signaling and Drought Response in Rice.

  2019cited by this paper
• Daytime temperature is sensed by phytochrome B in Arabidopsis through a transcriptional activator HEMERA

  2019cited by this paper
• Transcriptional and post-transcriptional regulation and transcriptional memory of chromatin regulators in response to low temperature

  2019cited by this paper
• H3K4me2 functions as a repressive epigenetic mark in plants

  2019cited by this paper
• Histone modifications and their regulatory roles in plant development and environmental memory.

  2019cited by this paper
• Overexpression of rice jacalin-related mannose-binding lectin (OsJAC1) enhances resistance to ionizing radiation in Arabidopsis

  2019cited by this paper
• Histone acetylation orchestrates wound-induced transcriptional activation and cellular reprogramming in Arabidopsis

  2019cited by this paper
• MYB96 recruits the HDA15 protein to suppress negative regulators of ABA signaling in Arabidopsis

  2019cited by this paper
• Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination

  2019cited by this paper
• The histone chaperoning pathway: from ribosome to nucleosome

  2019cited by this paper
• The mitogen-activated protein kinase 4-phosphorylated heat shock factor A4A regulates responses to combined salt and heat stresses

  2019cited by this paper
• Arabidopsis histone H3K4 demethylase JMJ17 functions in dehydration stress response.

  2019cited by this paper
• A membrane‐associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice

  2019cited by this paper
• Epigenetic signatures of stress adaptation and flowering regulation in response to extended drought and recovery in Zea mays.

  2019cited by this paper
• Histone Modifications Form Epigenetic Regulatory Networks to Regulate Abiotic Stress Response1[OPEN]

  2019cited by this paper
• Improved drought stress tolerance in Arabidopsis by CRISPR/dCas9 fusion with a Histone AcetylTransferase

  2019cited by this paper
• Epigenetic regulation in plant abiotic stress responses.

  2019cited by this paper
• Heat-shock proteins: chaperoning DNA repair

  2019cited by this paper
• Protein methylome analysis in Arabidopsis reveals regulation in RNA-related processes.

  2019cited by this paper
• Brachypodium histone deacetylase BdHD1 positively regulates ABA and drought stress responses.

  2019cited by this paper
• Cold stress induces enhanced chromatin accessibility and bivalent histone modifications H3K4me3 and H3K27me3 of active genes in potato

  2019cited by this paper
• CUT&Tag for efficient epigenomic profiling of small samples and single cells

  2019cited by this paper
• Bisulphite Sequencing of Chromatin Immunoprecipitated DNA (BisChIP-seq).

  2018cited by this paper
• How to Combine ChIP with qPCR.

  2018cited by this paper

• Effects of High Lithium Concentrations on the Growth, Biomass, Mineral Accumulation, Oxidative Stress, Antioxidant and Gene Expression Response, and DNA Methylation in Sunflower Plants

  2026cites this paper
• Decoding plant complexity through spatially resolved multi-omics approaches

  2026cites this paper
• Proposed Epigenetic Regulatory Frameworks at the Plant–Microbiome Interface Under Cadmium Stress

  2026cites this paper
• MECHANISMS OF ACTION AND SIGNALING PATHWAYS INVOLVED IN ABIOTIC STRESS ELICITATION

  2026cites this paper
• Plant osmosensors in next-generation smart agriculture: From innovation to application

  2025cites this paper
• Insights into molecular and biochemical approaches of multi-stress responses to horticultural crops

  2025cites this paper
• Epigenetic Regulation of Glucosinolate Biosynthesis: Mechanistic Insights and Breeding Prospects in Brassicaceae

  2025cites this paper
• Adapting Crops to Rising Temperatures: Understanding Heat Stress and Plant Resilience Mechanisms

  2025cites this paper
• Recent Advances and Application of Machine Learning for Protein–Protein Interaction Prediction in Rice: Challenges and Future Perspectives

  2025cites this paper
• A review of the advances and perspectives in sequencing technologies for analysing plant epigenetic responses to abiotic stress

  2025cites this paper
• Epigenetic mechanisms regulating plant responses to abiotic stress and their role in developing climate resilient crops

  2025cites this paper
• Cotton under heat stress: a comprehensive review of molecular breeding, genomics, and multi-omics strategies

  2025cites this paper
• Established and emerging roles of protein kinases in regulating primary sensory neurons in injury-and inflammation-associated pain

  2025cites this paper
• Molecular Insights Into Salt Stress Adaptation in Plants

  2025cites this paper
• Exploring the transgenerational epigenetic inheritance of drought stress responses in barley

  2025cites this paper
• A critical review on epigenetics and epigenomics in plant development and stress resilience

  2025cites this paper
• Genetic Associations of Multi-Generational Drought Stress: Physiological Responses and Yield Adaptations in Barley

  2025cites this paper
• Empowering rice resilience: elevating starch quality via seed priming amidst bio-molecular challenges during reproductive and maturation phases under drought stress

  2025cites this paper
• Heritable Epigenetic Changes in Plant Stress Responses: Implications for Crop Resilience

  2025cites this paper
• The Plant Mind: Unraveling Abiotic Stress Priming, Memory, and Adaptation

  2025cites this paper
• Effect of drought stress during critical developmental stages on morphological and grain yield-related traits in winter barley (Hordeum vulgare L.)

  2025cites this paper
• Unraveling histones: plant protectors under environmental stress unlocking the key to resilience

  2025cites this paper
• A Comprehensive Environmental and Molecular Strategy for the Evaluation of Fluroxypyr and Nature-Derived Compounds

  2025cites this paper
• Climate-Resilient Crops: Integrating AI, Multi-Omics, and Advanced Phenotyping to Address Global Agricultural and Societal Challenges

  2025cites this paper
• Epigenetic modulation in cancer drug discovery: promising targets and clinical applications

  2025cites this paper
• Exploring Multi‐Omics Tools and Their Advancement to Study Drought Stress Responses

  2025cites this paper
• A REVIEW: EXPLORING GENETIC VARIATION AND REGULATORY NETWORKS IN WHEAT HEAT STRESS TOLERANCE

  2024cites this paper
• Epigenetic control of gene expression by cellular metabolisms in plants.

  2024cites this paper
• Mapping proteomic response to salinity stress tolerance in oil crops: Towrads enhanced plant resilience

  2024cites this paper
• Cullin-Conciliated Regulation of Plant Immune Responses: Implications for Sustainable Crop Protection

  2024cites this paper
• Unlocking Plant Resilience: Advanced Epigenetic Strategies Against Heavy Metal and Metalloid Stress.

  2024cites this paper
• Abscisic acid enhances SmAPK1-mediated phosphorylation of SmbZIP4 to positively regulate tanshinone biosynthesis in Salvia miltiorrhiza.

  2024cites this paper