Pathogenicity islands: a molecular toolbox for bacterial virulence

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cellular Microbiology

• Publication date

  2006-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1462-5822.2006.00794.xPMID 16939533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interaction with CagF Is Required for Translocation of CagA into the Host via the Helicobacter pylori Type IV Secretion System

  2006influential reference
• A novel strategy for the identification of genomic islands by comparative analysis of the contents and contexts of tRNA sites in closely related bacteria

  2006cited by this paper
• Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection.

  2006cited by this paper
• Selective Silencing of Foreign DNA with Low GC Content by the H-NS Protein in Salmonella

  2006cited by this paper
• Evidence of a Large Novel Gene Pool Associated with Prokaryotic Genomic Islands

  2005influential reference
• Horizontal and vertical gene transfer: the life history of pathogens.

  2005cited by this paper
• University of Birmingham Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretion

  2005cited by this paper
• Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing Methicillin-Resistant Staphylococcus epidermidis Strain

  2005influential reference
• Helicobacter pylori–host cell interactions mediated by type IV secretion

  2005cited by this paper
• Pathogenicity island-dependent effects of Helicobacter pylori on intracellular signal transduction in epithelial cells.

  2005cited by this paper
• Enteropathogenic and Enterohemorrhagic Escherichia coli Infections: Translocation, Translocation, Translocation

  2005cited by this paper
• Lateral gene transfer in eukaryotes

  2005cited by this paper
• Pathogenicity islands and their role in bacterial virulence and survival.

  2005cited by this paper
• A plant natriuretic peptide-like gene in the bacterial pathogen Xanthomonas axonopodis may induce hyper-hydration in the plant host: a hypothesis of molecular mimicry

  2004cited by this paper
• Pathogenicity Islands in Bacterial Pathogenesis

  2004cited by this paper
• Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

  2004cited by this paper
• Dissecting virulence: systematic and functional analyses of a pathogenicity island.

  2004influential reference
• IslandPath: aiding detection of genomic islands in prokaryotes

  2003cited by this paper
• Virulence of Enteropathogenic Escherichia coli, a Global Pathogen

  2003cited by this paper
• Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus.

  2003cited by this paper
• Phage as agents of lateral gene transfer.

  2003cited by this paper
• Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin‐8

  2003cited by this paper
• Horizontal gene transfer and the evolution of parasitic protozoa.

  2003cited by this paper
• Reduced activation of inflammatory responses in host cells by mouse‐adapted Helicobacter pylori isolates

  2002influential reference
• Horizontal gene transfer in microbial genome evolution.

  2002cited by this paper
• Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3. Implications for the evolution of staphylococcal pathogenicity islands.

  2002cited by this paper
• Microbial minimalism: genome reduction in bacterial pathogens.

  2002cited by this paper
• A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic backgrounds.

  2002cited by this paper
• Genome-Based Identification of Chromosomal Regions Specific for Salmonella spp

  2002cited by this paper
• Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli

  2002cited by this paper
• Helicobacter pylori: impact of gene transfer and the role of the cag pathogenicity island for host adaptation and virulence.

  2002cited by this paper
• Common themes among bacteriophage-encoded virulence factors and diversity among the bacteriophages involved.

  2002cited by this paper
• Delivery of dangerous goods: type III secretion in enteric pathogens.

  2002cited by this paper
• Staphylococcus aureus enterotoxins: a key in airway disease?

  2002cited by this paper
• Complete Nucleotide Sequence and Analysis of the Locus of Enterocyte Effacement from Rabbit Diarrheagenic Escherichia coli RDEC-1

  2001cited by this paper
• Molecular genetics of SaPI1 – a mobile pathogenicity island in Staphylococcus aureus

  2001cited by this paper
• Ecological fitness, genomic islands and bacterial pathogenicity

  2001influential reference
• Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens

  2001cited by this paper
• A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2.

  2001cited by this paper
• The Yersinia high-pathogenicity island is present in different members of the family Enterobacteriaceae.

  2000cited by this paper
• Pathogenicity islands and the evolution of microbes.

  2000influential reference
• Parallel evolution of virulence in pathogenic Escherichia coli

  2000cited by this paper
• Horizontal gene transfer of glycosyl hydrolases of the rumen fungi.

  2000cited by this paper
• Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil

  2000cited by this paper
• Lateral gene transfer and the nature of bacterial innovation

  2000cited by this paper
• Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori.

  1999cited by this paper
• Phylogenetic Classification and the Universal Tree

  1999cited by this paper
• The mating-type and pathogenicity locus of the fungus Ustilago hordei spans a 500-kb region.

  1999cited by this paper
• A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria

  1999cited by this paper
• Phylogenetic Classification and the Universal Tree

  1999cited by this paper
• Phylogenetic classification and the universal tree.

  1999cited by this paper
• Genomic Analysis of a Pathogenicity Island in Uropathogenic Escherichia coli CFT073: Distribution of Homologous Sequences among Isolates from Patients with Pyelonephritis, Cystitis, and CatheterAssociated Bacteriuria and from Fecal Samples

  1998cited by this paper
• Prevalence of the “High-Pathogenicity Island” of Yersinia Species among Escherichia coliStrains That Are Pathogenic to Humans

  1998cited by this paper
• The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.

  1998cited by this paper
• The 102-Kilobase Unstable Region of Yersinia pestisComprises a High-Pathogenicity Island Linked to a Pigmentation Segment Which Undergoes Internal Rearrangement

  1998cited by this paper
• The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69

  1998cited by this paper
• The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus

  1998cited by this paper
• A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K‐12

  1997cited by this paper
• Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution

  1997cited by this paper
• Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins

  1997cited by this paper
• Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica

  1996influential reference
• Selfish operons: horizontal transfer may drive the evolution of gene clusters.

  1996cited by this paper
• Molecular genetic bases of Salmonella entry into host cells

  1996cited by this paper
• cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors.

  1996cited by this paper
• Pathogenicity islands: bacterial evolution in quantum leaps.

  1996cited by this paper
• Pathogenicity Islands: Minireview Bacterial Evolution in Quantum Leaps

  1996cited by this paper
• Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype.

  1995cited by this paper
• Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.

  1995cited by this paper
• A role for bacteriophages in the evolution and transfer of bacterial virulence determinants

  1995cited by this paper
• A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens.

  1995cited by this paper
• Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen

  1994influential reference
• Dynamics of the bacterial genome: deletions and integrations as mechanisms of bacterial virulence modulation.

  1993cited by this paper
• Loss of the pigmentation phenotype in Yersinia pestis is due to the spontaneous deletion of 102 kb of chromosomal DNA which is flanked by a repetitive element

  1992cited by this paper
• Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates.

  1990influential reference
• Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elements.

  1989cited by this paper
• Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration.

  1984cited by this paper
• Origin of Species

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