DEVELOPMENTAL ALCOHOL EXPOSURE IS EXHAUSTING: SLEEP AND THE ENDURING CONSEQUENCES OF ALCOHOL EXPOSURE DURING DEVELOPMENT.

Prenatal alcohol exposure is the leading nongenetic cause of human intellectual impairment. The long-term impacts of prenatal alcohol exposure on health and well-being are diverse, including neuropathology leading to behavioral, cognitive, and emotional impairments. Additionally negative effects also occur on the physiological level, such as the endocrine, cardiovascular, and immune systems. Among these diverse impacts is sleep disruption. In this review, we describe how prenatal alcohol exposure affects sleep, and potential mechanisms of those effects. Furthermore, we outline the evidence that sleep disruption across the lifespan may be a mediator of some cognitive and behavioral impacts of developmental alcohol exposure, and thus may represent a promising target for treatment.

• Publication year

  2024

• Venue

  Neuroscience and Biobehavioral Reviews

• Publication date

  2024-02-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.neubiorev.2024.105567PMID 38309498PMCID PMC10923002
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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