Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility

Simple Summary This review summarizes the main findings about the human seminal microbiome regarding its biological origins, microbial populations, and relationship with fertility and health, as well as the factors that may affect its composition and the potential sources of data variability. Abstract Although the microbial communities from seminal fluid were an unexplored field some decades ago, their characteristics and potential roles are gradually coming to light. Therefore, a complex and specific microbiome population with commensal niches and fluctuating species has started to be revealed. In fact, certain clusters of bacteria have been associated with fertility and health, while the outgrowth of several species is potentially correlated with infertility indicators. This constitutes a compelling reason for outlining the external elements that may induce changes in the seminal microbiome composition, like lifestyle factors, gut microbiota, pathologies, prebiotics, and probiotics. In this review, we summarize the main findings about seminal microbiome, its origins and composition, its relationship with fertility, health, and influence factors, while reminding readers of the limitations and advantages introduced from technical variabilities during the experimental procedures.

• Publication year

  2024

• Venue

  Biology

• Publication date

  2024-02-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3390/biology13030150PMID 38534419PMCID 10967773
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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