Detection of circulating tumor necrosis factor after endotoxin administration.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  New England Journal of Medicine

• Publication date

  1988-06-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJM198806093182301PMID 2835680
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biology of interleukin 1

  1988cited by this paper
• Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

  1987cited by this paper
• Lymphokines.

  1987cited by this paper
• The acute metabolic effects of tumor necrosis factor administration in humans.

  1987cited by this paper
• Development and use of a radioimmunoassay for human interleukin-1 beta.

  1987cited by this paper
• Phase I study of recombinant tumor necrosis factor in cancer patients.

  1987cited by this paper
• Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.

  1987cited by this paper
• Cachectin: more than a tumor necrosis factor.

  1987cited by this paper
• The regulation of ACTH secretion by IL-1.

  1987cited by this paper
• A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock.

  1987cited by this paper
• Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

  1986cited by this paper
• Shock and tissue injury induced by recombinant human cachectin.

  1986cited by this paper
• Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin).

  1986cited by this paper
• Cachectin and tumour necrosis factor as two sides of the same biological coin

  1986cited by this paper
• Raised serum levels of tumour necrosis factor in parasitic infections.

  1986cited by this paper
• Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma.

  1986cited by this paper
• Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.

  1986cited by this paper
• Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin.

  1985cited by this paper
• Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo.

  1985cited by this paper
• Use of monoclonal antibodies as sensitive and specific probes for biologically active human gamma-interferon.

  1984cited by this paper
• Studies of conditions and agents that stimulate and inhibit the production of cachectin by macrophages

  1984cited by this paper
• Combined Hormonal Infusion Simulates the Metabolic Response to Injury

  1984cited by this paper
• The processing and collaborative assay of a reference endotoxin.

  1983cited by this paper
• The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxim.

  1980cited by this paper
• Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome.

  1968cited by this paper

• Oral Treatment with the Vimentin-Targeting Compound ALD-R491 Mitigates Hyperinflammation, Multi-Organ Injury, and Mortality in CLP-Induced Septic Mice

  2025cites this paper
• Profile of NT-0527, a brain penetrant NLRP3 Inflammasome inhibitor suitable as an in vivo tool compound for neuroinflammatory disorders.

  2025cites this paper
• Efficacy of disinfectants and endotoxin-retentive filters for the removal of bacterial DNA from dialysates

  2025cites this paper
• 2023 Semmelweis Lecture: Sepsis Is a Myth*

  2025cites this paper
• Mitochondria at the Heart of Sepsis: Mechanisms, Metabolism, and Sex Differences

  2025cites this paper
• Efficiency of IL-6 in Early Prognosis and Follow-Up in Critically Ill Patients with Septic Shock

  2024cites this paper
• Validity of Mental and Physical Stress Models.

  2024cites this paper
• The translational potential of inflammation-induced skin blister human models in exploring the pathogenesis of periodontitis and its systemic health implications

  2024cites this paper
• Antipyretic Use in Noncritically Ill Patients With Fever: A Review

  2024cites this paper
• Stress responses to bacterial and viral mimetics in polycystic ovary syndrome model rats

  2024cites this paper
• Effects of metal corrosion in the pump of a dialysis machine on the sterility of the terminal dialysate by spike-and-recovery testing with bacteria

  2024cites this paper
• Toll-like receptor 4 promotes the inflammatory response in septic acute kidney injury by promoting p38 mitogen-activated protein kinase phosphorylation

  2023cites this paper
• Impact of Treatment with Antioxidants as an Adjuvant to Standard Therapy in Patients with Septic Shock: Analysis of the Correlation between Cytokine Storm and Oxidative Stress and Therapeutic Effects

  2023cites this paper
• TNF-α Limits Serological Memory by Disrupting the Bone Marrow Niche.

  2023cites this paper
• First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation

  2023cites this paper
• Focused ultrasound neuromodulation of the spleen activates an anti-inflammatory response in humans

  2023cites this paper
• SUBCLINICAL KIDNEY INJURY IS CAUSED BY A MODERATE SINGLE INFLAMMATORY EVENT

  2022cites this paper
• Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation

  2022cites this paper
• Ferret acute lung injury model induced by repeated nebulized lipopolysaccharide administration

  2022cites this paper
• Biomarkers in cardiogenic shock.

  2022cites this paper
• Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial

  2022cites this paper
• Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

  2022cites this paper
• Hypoxia and Cigarette Smoke - A Combined Threat to the Brain: Role of Toll-like Receptor 4 in Neuroinflammatory Changes

  2022cites this paper
• Immune Deregulation in Sepsis and Septic Shock: Reversing Immune Paralysis by Targeting PD-1/PD-L1 Pathway

  2021cites this paper
• The Effects of S-Allyl Cysteıne on Inflammatory Cascade in Lipopolysaccharide Induced Rat Sepsis Model

  2021cites this paper
• Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice

  2021influential citation
• Generalized Shwartzman Reaction as an Experimental Endotoxin Shock Model: Role of Intermediate T Cell Receptor-Expressing Innate T Lymphocytes in its Pathogenesis

  2021cites this paper
• New Decade, Old Debate: Blocking the Cytokine Pathways in Infection-Induced Cytokine Cascade

  2021cites this paper
• Tissue-Nonspecific Alkaline Phosphatase in Central Nervous System Health and Disease: A Focus on Brain Microvascular Endothelial Cells

  2021cites this paper
• Pre-treatment and continuous administration of simvastatin during sepsis improve metabolic parameters and prevent CNS injuries in survivor rats

  2021cites this paper
• Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway

  2021cites this paper
• Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.

  2021cites this paper
• Endothelial Dysfunction and Systemic Inflammation in the Pathogenesis and Progression of Portal Hypertension

  2021cites this paper
• Pro-oxidant and degenerative effects of haloperidol under inflammatory conditions in rat; the involvement of SIRT1 and NF-κB signaling pathways

  2021cites this paper
• Simultaneous Inhibition of Three Major Cytokines and Its Therapeutic Effects: A Peptide-Based Novel Therapy against Endotoxemia in Mice

  2021cites this paper
• 50 Years of Sepsis Investigation/Enlightenment Among Adults-The Long and Winding Road.

  2021cites this paper
• Cloning and expression analysis of Keap1 of golden pompano (Trachinotus ovatus) and response to oxidized fish oil and LPS administration

  2020cites this paper
• Therapeutic Potential of Rhododendron arboreum Polysaccharides in an Animal Model of Lipopolysaccharide-Inflicted Oxidative Stress and Systemic Inflammation

  2020cites this paper
• Immediate Cytokine Responses to Endotoxin: Tumor Necrosis Factor-α and the lnterleukin-1 Family

  2020cites this paper
• FAM96A knock‐out promotes alternative macrophage polarization and protects mice against sepsis

  2020cites this paper
• Zingerone [4-(3-Methoxy-4-hydroxyphenyl)-butan-2] Attenuates Lipopolysaccharide-Induced Inflammation and Protects Rats from Sepsis Associated Multi Organ Damage

  2020cites this paper
• Protective effects of honey and bee venom against lipopolysaccharide and carbon tetrachloride-induced hepatoxicity and lipid peroxidation in rats.

  2020cites this paper
• A Humanized Diet Profile May Facilitate Colonization and Immune Stimulation in Human Microbiota-Colonized Mice

  2020cites this paper
• Peptide-Based TNF-α-Binding Decoy Therapy Mitigates Lipopolysaccharide-Induced Liver Injury in Mice

  2020influential citation
• Addressing Nanomaterial Immunosafety by Evaluating Innate Immunity across Living Species.

  2020cites this paper
• LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway

  2020cites this paper
• Effects of two probiotic spores of Bacillus species on hematological, biochemical, and inflammatory parameters in Salmonella Typhimurium infected rats

  2020cites this paper
• Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent

  2020cites this paper
• Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy

  2019cites this paper
• Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction

  2019cites this paper
• Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice

  2019influential citation
• Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Not Induced in Artificial Human Inflammation and Is Not Correlated with Inflammatory Response

  2019cites this paper
• Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

  2019cites this paper
• Clinical and paraclinical changes in experimental colisepticemia in neonatal calves

  2019cites this paper
• Humoral Mediators in Sepsis

  2019cites this paper
• The design of a cell-selective fowlicidin-1-derived peptide with both antimicrobial and anti-inflammatory activities.

  2019cites this paper
• Septic Shock

  2018cites this paper
• Macrophages from Mice Administered Rhus verniciflua Stokes Extract Show Selective Anti-Inflammatory Activity

  2018cites this paper
• The systemic inflammatory response syndrome

  2018cites this paper
• Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-κB signaling suppression.

  2018cites this paper
• Garcinia Multiflora Inhibits FPR1-Mediated Neutrophil Activation and Protects Against Acute Lung Injury

  2018cites this paper
• Thymoquinone reduces mortality and suppresses early acute inflammatory markers of sepsis in a mouse model.

  2018cites this paper
• Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis

  2018cites this paper
• Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

  2018cites this paper
• Compound Ammonium Glycyrrhizin Protects Hepatocytes from Injury Induced by Lipopolysaccharide/Florfenicol through a Mitochondrial Pathway

  2018cites this paper
• [Development of views on pathophysiology of sepsis].

  2018cites this paper
• Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival

  2018cites this paper
• Systemic side effects of isolated limb perfusion with tumor necrosis factor alpha

  2018cites this paper
• Rat, akut peritonit modelinde klinik semptomlar ve hastalığın tedavisine oral strontium ranilat uygulamalarının etkilerinin araştırılması

  2018cites this paper
• Canine Acute Phase Respomse : Relationship Phase Protein in Dogs between Serum Cytokine Activity and Acute

  2017cites this paper
• Therapeutic approaches for the delivery of TNF-α siRNA.

  2017cites this paper
• Activation of the endothelium by pathogen-associated molecular patterns from Escherichia coli and Staphylococcus aureus

  2017cites this paper
• Exploration of the Mechanisms of Adjuvanticity for Toll-like Receptor Agonists

  2017cites this paper
• 130 – Neonatal Pulmonary Host Defense

  2017cites this paper
• Ammonium glycyrrhizin counteracts liver injury caused by lipopolysaccharide/amoxicillin-clavulanate potassium

  2017cites this paper
• Which one is more effective for the treatment of rat sepsis model: thalidomide or etanercept?

  2017cites this paper
• Cyclosporine counteracts endotoxemia‐evoked reductions in blood pressure and cardiac autonomic dysfunction via central sGC/MAPKs signaling in rats

  2017cites this paper
• Screening cytokine/chemokine profiles in serum and organs from an endotoxic shock mouse model by LiquiChip

  2017cites this paper
• Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

  2017cites this paper
• 6‐Hydroxy‐5,7‐dimethoxy‐flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury

  2017cites this paper
• Ammonium glycyrrhizin counteracts liver injury caused by lipopolysaccharide/amoxicillin-clavulanate potassium.

  2017cites this paper
• Microvascular endothelial responses in critical illness

  2017cites this paper
• Zingerone Suppresses the Shedding of Endothelial Protein C Receptor

  2017cites this paper
• Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis

  2017cites this paper
• Experimental Sepsis Severity Score Associated to Mortality and Bacterial Spreading is Related to Bacterial Load and Inflammatory Profile of Different Tissues

  2017cites this paper
• Use of Complementary and Alternative Therapies in Hepatic Disorders

  2017cites this paper
• Correlation between Proinflammatory Cytokines and Antiinflammatory Mediators and the Severity of Disease in Meningococcal Infections

  2017cites this paper
• UvA-DARE ( Digital Academic Repository ) The decrease in nonsplenic interleukin-6 ( IL-6 ) production after splenectomy indicates the existence of a psoitive feedback loop of IL-6 production during endotixemia in dogs

  2017cites this paper
• Concomitant effect of low dose of lindane and intranasal lipopolysaccharide on respiratory system of mice

  2017cites this paper
• MULTIPLE ORGAN DYSFUNCTION SYNDROME

  2017cites this paper
• Oxidative stress parameters and inflammatory and immune mediators as markers of the severity of sepsis.

  2016cites this paper
• Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-Derived Erythropoietin and Anemia.

  2016cites this paper
• CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Cytokine-Release Syndrome in Patients With B-Cell Chronic Lymphocytic Leukemia and High Lymphocyte Counts After Treatment With an Anti-CD20 Monoclonal Antibody (Rituximab, IDEC-C2B8)

  2016cites this paper
• Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

  2016cites this paper
• Regulation of Podocyte apoptosis in Diabetic Kidney Disease - Role of SHIP2, PDK1 and CDK2

  2016cites this paper
• Functional analysis of epithelium-specific Ets transcription factor-1 in inflammation

  2016cites this paper
• Non-Steroidal Anti-Inflammatory Drug Effects On Core Temperature, Hydration, Gastrointestinal Distress, And Performance In Exercising Humans

  2016cites this paper
• Suppressive Effects of Pelargonidin on Endothelial Protein C Receptor Shedding via the Inhibition of TACE Activity and MAP Kinases.

  2016cites this paper
• Physiologic Rationale, Diagnostic Implications, and Clinical Consequences

  2016cites this paper
• Antiparasitic and disease-modifying activity of Nyctanthes arbor-tristis Linn. in malaria: An exploratory clinical study

  2016cites this paper