Recurrent mutations in genes involved in nuclear factor‐κB signalling in nodal marginal zone lymphoma—diagnostic and therapeutic implications

M. Brand,J. Rijntjes,K. Hebeda,Laura Menting,Carolyn V Bregitha,W. Stevens,W. Velden,B. Tops,J. H. Krieken,P. Groenen

Published 2017 in Histopathology

ABSTRACT

To investigate the spectrum of mutations in 20 genes involved in B‐cell receptor and/or Toll‐like receptor signalling resulting in activation of nuclear factor‐κB (NF‐κB) in 20 nodal marginal zone lymphomas (NMZLs), 20 follicular lymphomas (FLs), and 11 cases of B‐cell lymphoma, unclassifiable (BCL‐u).

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