Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Immunity

• Publication date

  2005-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.IMMUNI.2005.10.007PMID 16356856
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

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• Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.

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• CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

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• MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF-κB Activation*

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• The immunological synapse.

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• PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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