Terpenoids are ubiquitous to all kingdoms of life and are one of the most diverse groups of compounds, both structurally and functionally. Despite being derived from common precursors, isopentenyl diphosphate and dimethylallyl diphosphate, their exceptional diversity is partly driven by the substrate and product promiscuity of terpene synthases that produce a wide array of terpene skeletons. Plant terpene synthases can be subdivided into different subfamilies based on sequence homology and function. However, in many cases, structural architecture of the enzyme is more essential to product specificity than primary sequence alone, and distantly related terpene synthases can often mediate similar reactions. As such, the focus of this brief review is on some of the recent progress in understanding terpene synthase function and diversity.
Plant specialized metabolism: Diversity of terpene synthases and their products.
Matthew E. Bergman,Natalia Dudareva
Published 2024 in Current opinion in plant biology
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- Publication year
2024
- Venue
Current opinion in plant biology
- Publication date
2024-07-24
- Fields of study
Biology, Medicine, Chemistry, Environmental Science
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Semantic Scholar, PubMed
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