Mechanistic insight of neurodegeneration due to micro/nano-plastic-induced gut dysbiosis

No abstract is available for this paper.

• Publication year

  2024

• Venue

  Archives of Toxicology

• Publication date

  2024-10-06

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00204-024-03875-3PMID 39370473
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Impact of nanoplastics on Alzheimer 's disease: Enhanced amyloid-β peptide aggregation and augmented neurotoxicity.

  2024influential reference
• Microbiota-mediated metabolic perturbations in the gut and brain of mice after microplastic exposure.

  2023cited by this paper
• Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine.

  2023influential reference
• Combined exposure of polystyrene microplastics and carbamazepine induced transgenerational effects on the reproduction of Daphnia magna

  2023cited by this paper
• Are microplastics contributing to pollution-induced neurotoxicity? A pilot study with wild fish in a real scenario

  2023cited by this paper
• Oral Exposure to Polystyrene Microplastics of Mice on a Normal or High-Fat Diet and Intestinal and Metabolic Outcomes

  2023cited by this paper
• Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

  2023cited by this paper
• Microplastics: Detection in human samples, cell line studies, and health impacts.

  2023cited by this paper
• The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways.

  2023cited by this paper
• Acute Exposure to Microplastics Induced Changes in Behavior and Inflammation in Young and Old Mice

  2023cited by this paper
• Human Microplastics Exposure and Potential Health Risks to Target Organs by Different Routes: A Review

  2023cited by this paper
• Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and DEHP.

  2023influential reference
• Polystyrene microplastics disrupted physical barriers, microbiota composition and immune responses in the cecum of developmental Japanese quails.

  2023cited by this paper
• Exposure to Polystyrene Microplastics Promotes the Progression of Cognitive Impairment in Alzheimer’s Disease: Association with Induction of Microglial Pyroptosis

  2023cited by this paper
• Polystyrene microplastics induce size-dependent multi-organ damage in mice: Insights into gut microbiota and fecal metabolites.

  2023cited by this paper
• PTBP1 as a potential regulator of disease

  2023cited by this paper
• The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances

  2023cited by this paper
• Polystyrene microplastics aggravate inflammatory damage in mice with intestinal immune imbalance.

  2022influential reference
• An insight into sex-specific neurotoxicity and molecular mechanisms of DEHP: A critical review.

  2022cited by this paper
• Effects of Polystyrene Microplastics on Human Kidney and Liver Cell Morphology, Cellular Proliferation, and Metabolism

  2022cited by this paper
• Deeply in Plasticenta: Presence of Microplastics in the Intracellular Compartment of Human Placentas

  2022cited by this paper
• Microplastics detected in cirrhotic liver tissue

  2022cited by this paper
• Polyvinyl chloride microplastics induced gut barrier dysfunction, microbiota dysbiosis and metabolism disorder in adult mice.

  2022influential reference
• Bile acid metabolism and signaling, the microbiota, and metabolic disease.

  2022cited by this paper
• Inflammation From Peripheral Organs to the Brain: How Does Systemic Inflammation Cause Neuroinflammation?

  2022cited by this paper
• Embryotoxicity of Polystyrene Microspheres of Different Sizes to the Marine Medaka Oryzias melastigma (McClelland, 1839)

  2022influential reference
• Effects of hybrid nanoparticle additives in n-butanol/waste plastic oil/diesel blends on combustion, particulate and gaseous emissions from diesel engine evaluated with entropy-weighted PROMETHEE II and TOPSIS: Environmental and health risks of plastic waste

  2022cited by this paper
• Integrated analysis of multi-tissues lipidome and gut microbiome reveals microbiota-induced shifts on lipid metabolism in pigs

  2022cited by this paper
• Microplastics exposure affects neural development of human pluripotent stem cell-derived cortical spheroids.

  2022influential reference
• Towards a Circular Economy of Plastics: An Evaluation of the Systematic Transition to a New Generation of Bioplastics

  2022cited by this paper
• Polystyrene microplastics affect learning and memory in mice by inducing oxidative stress and decreasing the level of acetylcholine.

  2022influential reference
• Co-exposure of polystyrene microplastics and iron aggravates cognitive decline in aging mice via ferroptosis induction.

  2022influential reference
• Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson's disease-like neurodegeneration by causing energy metabolism disorders in mice.

  2022influential reference
• The Potential Role of Gut Microbiota in Alzheimer’s Disease: From Diagnosis to Treatment

  2022cited by this paper
• Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice.

  2022cited by this paper
• Gut microbiome and health: mechanistic insights

  2022cited by this paper
• Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach.

  2022cited by this paper
• PET microplastics affect human gut microbiota communities during simulated gastrointestinal digestion, first evidence of plausible polymer biodegradation during human digestion

  2022cited by this paper
• Erratum: “Evaluation of Neurotoxicity in BALB/c Mice following Chronic Exposure to Polystyrene Microplastics”

  2022cited by this paper
• Short-Term Exposure to MPs and DEHP Disrupted Gill Functions in Marine Bivalves

  2022cited by this paper
• Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression

  2021cited by this paper
• Plastic nanoparticles cause mild inflammation, disrupt metabolic pathways, change the gut microbiota and affect reproduction in zebrafish: A full generation multi-omics study.

  2021cited by this paper
• Nanoplastics-induced oxidative stress, antioxidant defense, and physiological response in exposed Wistar albino rats

  2021cited by this paper
• Phthalate metabolites: Characterization, toxicities, global distribution, and exposure assessment.

  2021cited by this paper
• Detrimental effects of microplastic exposure on normal and asthmatic pulmonary physiology.

  2021cited by this paper
• PET microplastics affect human gut microbiota communities during simulated gastrointestinal digestion, first evidence of plausible polymer biodegradation during human digestion

  2021cited by this paper
• Chronic exposure to UV-aged microplastics induces neurotoxicity by affecting dopamine, glutamate, and serotonin neurotransmission in Caenorhabditis elegans.

  2021cited by this paper
• Polystyrene microplastics induce microbial dysbiosis and dysfunction in surrounding seawater.

  2021cited by this paper
• Microparticles and microplastics released from daily use of plastic feeding and water bottles and plastic injectors: potential risks to infants and children in China

  2021cited by this paper
• Acute and Sub-Chronic Effects of Microplastics (3 and 10 µm) on the Human Intestinal Cells HT-29

  2021cited by this paper
• Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice.

  2021influential reference
• Polystyrene nanoplastics alter virus replication in orange-spotted grouper (Epinephelus coioides) spleen and brain tissues and spleen cells.

  2021cited by this paper
• In-vitro evaluation of antioxidant and anticholinesterase activities of novel pyridine, quinoxaline and s-triazine derivatives.

  2021cited by this paper
• Ameliorative Role of Cerium Oxide Nanoparticles Against Fipronil Impact on Brain Function, Oxidative Stress, and Apoptotic Cascades in Albino Rats

  2021cited by this paper
• Polystyrene Microplastics Reduce Abundance Of Developing B Cells In Rainbow Trout (Oncorhynchus Mykiss) Primary Cultures.

  2021cited by this paper
• Polystyrene microplastics induce blood–testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats

  2021cited by this paper
• The Oral-Gut-Brain AXIS: The Influence of Microbes in Alzheimer’s Disease

  2021cited by this paper
• Microplastics in the human digestive environment: A focus on the potential and challenges facing in vitro gut model development.

  2021cited by this paper
• Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction

  2021cited by this paper
• The Microbiota-Gut-Brain Axis: From Motility to Mood.

  2021cited by this paper
• Plasticenta: First evidence of microplastics in human placenta.

  2021cited by this paper
• The fate of plastic in the ocean environment - a minireview.

  2021cited by this paper
• Polystyrene microplastics induced male reproductive toxicity in mice.

  2020cited by this paper
• Microplastic ingestion induces behavioral disorders in mice: A preliminary study on the trophic transfer effects via tadpoles and fish.

  2020cited by this paper
• Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut.

  2020cited by this paper
• The Association of Post-Stroke Cognitive Impairment and Gut Microbiota and its Corresponding Metabolites

  2020cited by this paper
• Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier

  2020cited by this paper
• The gut microbiota–brain axis in behaviour and brain disorders

  2020cited by this paper
• The plastic brain: neurotoxicity of micro- and nanoplastics

  2020cited by this paper
• Environmental exposure enhances the internalization of microplastic particles into cells

  2020cited by this paper
• Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation

  2020cited by this paper
• Interaction between microbiota and immunity in health and disease

  2020cited by this paper
• The Role of Gut Microbiome in Psoriasis: Oral Administration of Staphylococcus aureus and Streptococcus danieliae Exacerbates Skin Inflammation of Imiquimod-Induced Psoriasis-Like Dermatitis

  2020cited by this paper
• Effect of functional food ingredients on gut microbiota in a rodent diabetes model

  2020influential reference
• Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation.

  2020cited by this paper
• Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

  2020cited by this paper
• Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health

  2020cited by this paper
• Uptake and cellular effects of PE, PP, PET and PVC microplastic particles.

  2020cited by this paper
• The Microbiome as a Modifier of Neurodegenerative Disease Risk.

  2020cited by this paper
• Review of micro- and nanoplastic contamination in the food chain

  2019cited by this paper
• The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

  2019cited by this paper
• Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells.

  2019cited by this paper
• Emergence of Nanoplastic in the Environment and Possible Impact on Human Health.

  2019cited by this paper
• Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology

  2019cited by this paper
• Microplastics in freshwaters and drinking water: Critical review and assessment of data quality

  2019cited by this paper
• Gut Microbe to Brain Signaling: What Happens in Vagus….

  2019cited by this paper
• The Role of the Cell Surface Mucin MUC1 as a Barrier to Infection and Regulator of Inflammation

  2019cited by this paper
• Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis.

  2019cited by this paper
• The role of short-chain fatty acids in microbiota–gut–brain communication

  2019cited by this paper
• Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment

  2019cited by this paper
• Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo

  2019cited by this paper
• Polystyrene microplastics ingestion induced behavioral effects to the cladoceran Daphnia magna.

  2019cited by this paper
• Human Consumption of Microplastics.

  2019cited by this paper
• Particulate plastics as a vector for toxic trace-element uptake by aquatic and terrestrial organisms and human health risk.

  2019cited by this paper
• Altered Gut Microbiome in Parkinson’s Disease and the Influence of Lipopolysaccharide in a Human α-Synuclein Over-Expressing Mouse Model

  2019cited by this paper
• The Microbiota-Gut-Brain Axis.

  2019cited by this paper
• Uptake of Microplastics by Plant: a Reason to Worry or to be Happy?

  2019cited by this paper
• Microplastics and their possible sources: The example of Ofanto river in southeast Italy.

  2019influential reference
• Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish

  2019cited by this paper
• Environmental exposure to microplastics: An overview on possible human health effects.

  2019cited by this paper

• Chronic Starch-Based Microplastic Exposure Enhances the Risk of Alzheimer's Disease in Mice by Perturbing the Gut-Brain Axis.

  2026cites this paper
• Micro/nanoplastic-mediated gut dysbiosis and its impact on cardiac and neuroimmune function in zebrafish model: A multi-omics approach.

  2026cites this paper
• Micro-nanoplastics in the central nervous system: evidence, mechanisms and perspectives.

  2026cites this paper
• Brain under siege: the role of micro and nanoplastics in neuroinflammation and oxidative stress

  2026cites this paper
• Imperative implication of microplastics as vital agent for salmonellosis inducing biofilms, antibiotic resistance, and health risk.

  2026cites this paper
• Microplastic contamination in kidney transplant donor tissues and its association with early post-transplant blood pressure changes in recipients: A multi-modal analytical study.

  2025cites this paper
• The Human Plastiphere: A Bioparticulate System Challenging Microplastic Risk Assessment and Governance

  2025cites this paper
• Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects

  2025cites this paper
• Microbial Influences on Amyotrophic Lateral Sclerosis: The Gut–Brain Axis and Therapeutic Potential of Microbiota Modulation

  2025cites this paper
• Unraveling the molecular pathways linking polystyrene exposure and depression

  2025cites this paper
• Molecular and Cellular Effects of Microplastics and Nanoplastics in the Pathogenesis of Cardiovascular, Nervous, Urinary, Digestive, and Reproductive System Diseases: A Global Systematic Review

  2025cites this paper
• Micro-Bioplastic Impact on Gut Microbiome, Cephalic transcription and Cognitive Function in the aquatic invertebrate Daphnia magna.

  2025cites this paper
• Preliminary Study on PCC-Chitosan’s Ability to Enhance Microplastic Excretion in Human Stools from Healthy Volunteers

  2025cites this paper
• Polystyrene Accelerates Aging Related-Gut Microbiome Dysbiosis and -Metabolites in Old-Aged Mouse

  2025cites this paper
• Effects of Microplastics and Nanoplastics Exposure on Neurogenesis: Are Thymidine Analogs a Good Option to Study Such Effects?

  2025cites this paper
• World Journal of Hepatology

  year unknowncites this paper