We demonstrate a novel method for measuring the microrheology of soft viscoelastic media, based on cross correlating the thermal motion of pairs of embedded tracer particles. The method does not depend on the exact nature of the coupling between the tracers and the medium, and yields accurate rheological data for highly inhomogeneous materials. We demonstrate the accuracy of this method with a guar solution, for which other microscopic methods fail due to the polymer's mesoscopic inhomogeneity. Measurements in an F-actin solution suggest conventional microrheology measurements may not reflect the true bulk behavior.
Two-point microrheology of inhomogeneous soft materials.
J. Crocker,M. Valentine,E. Weeks,T. Gisler,P. Kaplan,A. G. Yodh,D. Weitz
Published 2000 in Physical Review Letters
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PUBLICATION RECORD
- Publication year
2000
- Venue
Physical Review Letters
- Publication date
2000-07-24
- Fields of study
Medicine, Materials Science, Physics
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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