Reversal of myogenic terminal differentiation by SV40 large T antigen results in mitosis and apoptosis.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Cell Science

• Publication date

  1998-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 9512504
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Induction of apoptosis by the transcription factor c‐Jun

  1997cited by this paper
• Integrins, adhesion and apoptosis.

  1997cited by this paper
• Caspases: the executioners of apoptosis.

  1997cited by this paper
• Suppression of interleukin-1beta converting enzyme (ICE)-induced apoptosis by SV40 large T antigen.

  1997cited by this paper
• Temporal and spatial expression of distinct troponin T genes in embryonic/larval tail striated muscle and adult body wall smooth muscle of ascidian.

  1997cited by this paper
• Amphibian Limb Regeneration: Rebuilding a Complex Structure

  1997cited by this paper
• p53, the Cellular Gatekeeper Review for Growth and Division

  1997cited by this paper
• Integrins and anoikis.

  1997cited by this paper
• Newt Myotubes Reenter the Cell Cycle by Phosphorylation of the Retinoblastoma Protein

  1997cited by this paper
• Suppression of Interleukin-1β converting enzyme (ICE)-induced apoptosis by SV40 large T antigen

  1997cited by this paper
• Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

  1996influential reference
• Induction of c-myc mediated apoptosis in SV40-transformed rat fibroblasts.

  1996cited by this paper
• Distinct Troponin T Genes Are Expressed in Embryonic/Larval Tail Striated Muscle and Adult Body Wall Smooth Muscle of Ascidian*

  1996cited by this paper
• Resistance to Apoptosis Conferred by Cdk Inhibitors During Myocyte Differentiation

  1996influential reference
• Induction of c-myc mediated apoptosis in SV40-transformed rat fibroblasts.

  1996cited by this paper
• pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

  1996cited by this paper
• Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD

  1995cited by this paper
• Mitotic cycle reactivation in terminally differentiated cells by adenovirus infection

  1995cited by this paper
• Simian Virus 40 T Antigen-induced Amplification of Pre-parietal Cells in Transgenic Mice.

  1995cited by this paper
• Compensatory apoptosis in response to SV40 large T antigen expression in the liver.

  1995cited by this paper
• Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: evidence of apoptosis in dystrophin-deficient muscle.

  1995cited by this paper
• Programmed cell death in dystrophic (mdx) muscle is inhibited by IGF-II.

  1995cited by this paper
• Apoptosis precedes necrosis of dystrophin-deficient muscle.

  1995cited by this paper
• Spatial, temporal and hormonal regulation of programmed muscle cell death during metamorphosis of the frog Xenopus laevis.

  1995cited by this paper
• Inhibition of apoptosis by the retinoblastoma gene product.

  1995cited by this paper
• p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

  1995cited by this paper
• SV40 large T antigen reinduces the cell cycle in terminally differentiated myotubes through inducing Cdk2, Cdc2, and their partner cyclins.

  1994influential reference
• Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells.

  1994influential reference
• Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.

  1994cited by this paper
• Apoptosis is induced at nonpermissive temperature by a transient increase in p53 in cell lines immortalized with temperature-sensitive SV40 large T-antigen gene.

  1994cited by this paper
• Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.

  1994cited by this paper
• The transforming activity of simian virus 40 large tumor antigen.

  1994cited by this paper
• p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

  1994cited by this paper
• Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

  1994cited by this paper
• Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development.

  1994cited by this paper
• Endonuclease activities associated with high molecular weight and internucleosomal DNA fragmentation in apoptosis.

  1994cited by this paper
• Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

  1993cited by this paper
• Reversal of muscle differentiation during urodele limb regeneration.

  1993cited by this paper
• Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation.

  1993cited by this paper
• Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

  1993cited by this paper
• Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation.

  1993cited by this paper
• Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

  1992cited by this paper
• Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines.

  1992cited by this paper
• Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation.

  1992cited by this paper
• The induction of apoptosis by chemotherapeutic agents occurs in all phases of the cell cycle.

  1992cited by this paper
• Retinoblastoma gene product Rb accumulates during myogenic differentiation and is deinduced by the expression of SV40 large T antigen.

  1992influential reference
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• SV40 large T inhibits myogenic differentiation partially through inducing c-jun.

  1992influential reference
• Microsurgical removal of centrosomes blocks cell reproduction and centriole generation in BSC-1 cells.

  1991cited by this paper
• A complex containing p34cdc2 and cyclin B phosphorylates the nuclear lamin and disassembles nuclei of clam oocytes in vitro

  1991cited by this paper
• A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle.

  1991cited by this paper
• Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

  1991cited by this paper
• Apoptosis: mechanisms and roles in pathology.

  1991cited by this paper
• Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

  1991cited by this paper
• p34cdc2 kinase is localized to distinct domains within the mitotic apparatus.

  1990cited by this paper
• SV40 immortalizes myogenic cells: DNA synthesis and mitosis in differentiating myotubes.

  1990influential reference
• Universal control mechanism regulating onset of M-phase

  1990cited by this paper
• Microinjection of p34cdc2 kinase induces marked changes in cell shape, cytoskeletal organization, and chromatin structure in mammalian fibroblasts.

  1990cited by this paper
• SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family.

  1989cited by this paper
• The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells.

  1989cited by this paper
• p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

  1989cited by this paper
• Distribution of microtubules and other cytoskeletal filaments during myotube elongation as revealed by fluorescence microscopy

  1988cited by this paper
• Centrioles are lost as embryonic myoblasts fuse into myotubes in vitro.

  1986cited by this paper
• Expression of multiple troponin T variants in neonatal chicken breast muscle.

  1986cited by this paper
• Transcriptional and posttranscriptional control of c-myc during myogenesis: its mRNA remains inducible in differentiated cells and does not suppress the differentiated phenotype

  1986cited by this paper
• Fate of microtubule-organizing centers during myogenesis in vitro

  1985cited by this paper
• The biology of cell reproduction

  1985cited by this paper
• Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

  1984cited by this paper
• Cytoplasmic activation of human nuclear genes in stable heterocaryons.

  1983cited by this paper
• Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro

  1982cited by this paper
• Cell death: the significance of apoptosis.

  1980cited by this paper
• Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

  1980cited by this paper
• Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

  1977cited by this paper
• The relationship of polyoma virus-induced tumor (T) antigen to activation of DNA synthesis in rat myotubes.

  1973cited by this paper
• Cellular aspects of muscle differentiation in vitro.

  1969cited by this paper
• Multinucleated Muscle Fibres: Induction of DNA Synthesis and Mitosis by Polyoma Virus Infection

  1967cited by this paper
• Infection of muscle cultures from various species with oncogenic DNA viruses (SV40 and polyoma).

  1967cited by this paper
• The biology of cells

  1965cited by this paper
• DNA synthesis and myogenesis.

  1961cited by this paper
• THE DISSOCIABILITY OF DEOXYRIBONUCLEIC ACID SYNTHESIS FROM THE DEVELOPMENT OF MULTINUCLEARITY OF MUSCLE CELLS IN CULTURE

  1960cited by this paper

• Structural obstruction to full DNA replication in terminally differentiated skeletal muscle cells

  2025cites this paper
• Skeletal Muscle Nuclei in Mice are not Post-mitotic

  2022cites this paper
• Restoring the Cell Cycle and Proliferation Competence in Terminally Differentiated Skeletal Muscle Myotubes

  2021cites this paper
• Enamel biomimetics—fiction or future of dentistry

  2019cites this paper
• Epigenetic Regulation of Olfactory Receptor Genes and Dedifferentiation of an Olfactory Placode Cell Line

  2019cites this paper
• Facio-scapulo-humeral dystrophy: clinical follow-up and role of chromosome X inactivation in female patients - SHP2: a novel therapeutic target in MuSK-myasthenia

  2018cites this paper
• PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression

  2017cites this paper
• Lessons from the swamp: developing small molecules that confer salamander muscle cellularization in mammals

  2017cites this paper
• Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis

  2016cites this paper
• A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene

  2015cites this paper
• Delineating the regulation of energy homeostasis using hypothalamic cell models.

  2015cites this paper
• Syddansk Universitet A fine balance epigenetic control of cellular quiescence by the tumor suppressor PRDM 2 / RIZ at a bivalent domain in the cyclin a gene

  2015cites this paper
• Anti-Differentiation Effect of Oncogenic Met Receptor in Terminally-Differentiated Myotubes

  2015cites this paper
• Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression.

  2015cites this paper
• Facioscapulohumeral dystrophy: the path to consensus on pathophysiology

  2014cites this paper
• Reawakening atlas: chemical approaches to repair or replace dysfunctional musculature.

  2012cites this paper
• The Role of the Retinoblastoma Protein Family in Skeletal Myogenesis

  2011cites this paper
• Inhibitors of tyrosine phosphatases and apoptosis reprogram lineage-marked differentiated muscle to myogenic progenitor cells.

  2011cites this paper
• DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

  2010cites this paper
• M-Ras evolved independently of R-Ras and its neural function is conserved between mammalian and ascidian, which lacks classical Ras.

  2009cites this paper
• Retrodifferentiation – a mechanism for cellular regeneration?

  2009cites this paper
• Gene-Silencing von Adhäsionsmolekülrezeptorproteinen an Herzmuskelzellen zur transienten Myokardprotektion während extrakorporaler Zirkulation

  2009cites this paper
• Gene-Silencing von Adhäsionsmolekülrezeptorproteinen an Herzmuskelzellen zur transienten Myokardprotektion während extrakorporaler Zirkulation

  2009cites this paper
• Histone modifications and cellular plasticity in vertebrate Limb regeneration

  2008cites this paper
• Studies on HIF hydroxylases

  2008cites this paper
• Retinoblastoma tumor suppressor protein–dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit

  2007cites this paper
• A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila.

  2007cites this paper
• Retinoblastoma tumor suppressor protein – dependent methylation of histone H 3 lysine 27 is associated with irreversible cell cycle exit

  2007cites this paper
• Stem cells and plasticity of skeletal muscle cell differentiation: potential application to cell therapy for degenerative muscular diseases.

  2007cites this paper
• Sustained activation of M‐Ras induced by nerve growth factor is essential for neuronal differentiation of PC12 cells

  2006cites this paper
• Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.

  2006cites this paper
• A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR

  2006cites this paper
• Elevated expression of NF‐κB and Bcl‐2 proteins in C2C12 myocytes during myogenesis is affected by PD98059; LY294002 and SB203580

  2005cites this paper
• Stem cell, una alternativa al trasplante cardíaco en el tratamiento de la insuficiencia cardíaca

  2005cites this paper
• Adult bone marrow-derived stem cells and the injured heart: just the beginning?

  2005cites this paper
• Spontaneous cell transformation: Karyoplasts derived from multinucleated cells produce new cell growth in senescent human epithelial cell cultures

  2004cites this paper
• Myocyte differentiation generates nuclear invaginations traversed by myofibrils associating with sarcomeric protein mRNAs

  2004cites this paper
• How cells dedifferentiate: a lesson from plants.

  2004cites this paper
• The cellularisation of mammalian myotubes by myoseverin.

  2004cites this paper
• Chromatin reorganization accompanying cellular dedifferentiation is associated with modifications of histone H3, redistribution of HP1, and activation of E2F‐target genes

  2003cites this paper
• Electrotransfer in differentiated myotubes: a novel, efficient procedure for functional gene transfer.

  2003cites this paper
• Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth

  2003cites this paper
• Molecular characterization and differential expression of the myostatin gene in channel catfish (Ictalurus punctatus).

  2002cites this paper
• A novel approach to induce cell cycle reentry in terminally differentiated muscle cells

  2002cites this paper
• The Role of Stem Cells in Skeletal and Cardiac Muscle Repair

  2002cites this paper
• Inducing cellular dedifferentiation: a potential method for enhancing endogenous regeneration in mammals.

  2002cites this paper
• Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes.

  2002cites this paper
• The DNA damage response of rodent fibroblasts expressing all or part of Simian Virus 40 large T antigen

  2001cites this paper
• Transgenic Bcl-2 expressed in photoreceptor cells confers both death-sparing and death-inducing effects.

  2001cites this paper
• Caspase 3 Expression Correlates With Skeletal Muscle Apoptosis in Duchenne and Facioscapulo Human Muscular Dystrophy. A Potential Target for Pharmacological Treatment?

  2001cites this paper
• Mammalian myotube dedifferentiation induced by newt regeneration extract

  2001cites this paper
• Inducción de nuevos cardiomiocitos en el corazón adulto: futuro de la regeneración miocárdica como alternativa al trasplante

  2001cites this paper
• Plasticity of the differentiated state in adult newt cardiomyocytes

  2001cites this paper
• Compositions et procedes de dedifferenciation cellulaire et regeneration tissulaire

  2001cites this paper
• [Generation of new cardiomyocytes in the adult heart: Prospects of myocardial regeneration as an alternative to cardiac transplantation].

  2001cites this paper
• Long-term fate of terminally differentiated skeletal muscle cells following E1A-initiated cell cycle reactivation

  2000influential citation
• Degeneration of cone photoreceptors induced by expression of the Mas1 protooncogene.

  2000cites this paper
• Generation of mononucleate cells from post-mitotic myotubes proceeds in the absence of cell cycle progression.

  2000cites this paper
• Meltrin α cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src

  2000cites this paper
• The majority of human replication protein A remains complexed throughout the cell cycle.

  2000cites this paper
• Endogenous meltrin alpha is ubiquitously expressed and associated with the plasma membrane but exogenous meltrin alpha is retained in the endoplasmic reticulum.

  2000cites this paper
• Polyomavirus large T-antigen protects mouse cells from Fas-, TNF-alpha- and taxol-induced apoptosis.

  2000cites this paper
• Plasticity of retrovirus-labelled myotubes in the newt limb regeneration blastema.

  2000cites this paper
• Dedifferentiation of mammalian myotubes induced by msx1.

  2000cites this paper
• Apoptosis of skeletal muscles during development and disease.

  1999cites this paper
• Inhibition of SV40 large T antigen induced apoptosis by small T antigen

  1999cites this paper
• Small GTPase RhoD suppresses cell migration and cytokinesis

  1999cites this paper