Serum phenylalanine concentrations in patients with ovarian carcinoma correlate with concentrations of immune activation markers and of isoprostane-8.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cancer Letters

• Publication date

  2008-12-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.canlet.2008.07.002PMID 18701209
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Disorders of tetrahydrobiopterin metabolism and their treatment.

  2002influential reference
• Hyperhomocysteinemia, pteridines and oxidative stress.

  2002cited by this paper
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  2001cited by this paper
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  1994influential reference
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  1994cited by this paper
• Reactive oxygen species in living systems: source, biochemistry, and role in human disease.

  1991cited by this paper
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  1990cited by this paper
• Plasma amino acid pattern of patients with HIV infection.

  1988cited by this paper
• Phenylalanine: total amino acid ratio in 45 burn patients.

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• Elevated D-erythro-neopterin levels in intensive care patients with septic complications.

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  1986cited by this paper
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  1985cited by this paper
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  1984cited by this paper
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  1983cited by this paper
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  1979cited by this paper

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