Nuclear STK15 expression is associated with aggressive behaviour of oral carcinoma cells in vivo and in vitro

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Pathology

• Publication date

  2010-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/path.2737PMID 20597069
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oncogenic role of nuclear accumulated Aurora‐A

  2009cited by this paper
• Cell cycle and viral and immunologic profiles of head and neck squamous cell carcinoma as predictable variables of tumor progression

  2009cited by this paper
• Autophagy—A double‐edged sword in oncology

  2009cited by this paper
• Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.

  2009cited by this paper
• Life and death partners: apoptosis, autophagy and the cross-talk between them

  2009cited by this paper
• The signaling adaptor p 62 is a multidomain protein implicated in the activation of the transcription factor

  2009cited by this paper
• Hypoxia‐inducible enhancer/α‐fetoprotein promoter‐driven RNA interference targeting STK15 suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells

  2008cited by this paper
• Insulin‐like growth factor binding protein‐5 (IGFBP‐5) suppresses the tumourigenesis of head and neck squamous cell carcinoma

  2008cited by this paper
• Diet, Autophagy, and Cancer: A Review

  2008cited by this paper
• Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas.

  2008cited by this paper
• Transcriptional regulation of serine/threonine kinase-15 (STK15) expression by hypoxia and HIF-1.

  2008cited by this paper
• Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.

  2008cited by this paper
• TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

  2007cited by this paper
• Association of Expression Aberrances and Genetic Polymorphisms of Lysyl Oxidase with Areca-Associated Oral Tumorigenesis

  2007cited by this paper
• Low level STK15 amplification in histologically benign urothelium of patients with bladder cancer adversely predicts patient outcome following cystectomy.

  2007cited by this paper
• Perimembrane Aurora-A Expression is a Significant Prognostic Factor in Correlation with Proliferative Activity in Non-Small-Cell Lung Cancer (NSCLC)

  2007cited by this paper
• Constitutive Phosphorylation of Aurora-A on Ser51 Induces Its Stabilization and Consequent Overexpression in Cancer

  2007cited by this paper
• AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

  2006cited by this paper
• Expression of serine threonine kinase 15 is associated with poor differentiation in lung squamous cell carcinoma and adenocarcinoma

  2006cited by this paper
• The centrosome cycle.

  2006cited by this paper
• Autophagy and Cancer Therapy

  2006cited by this paper
• Fragile Histidine Triad Expression in Oral Squamous Cell Carcinoma and Precursor Lesions

  2006cited by this paper
• Aurora Kinase A Messenger RNA Overexpression Is Correlated with Tumor Progression and Shortened Survival in Head and Neck Squamous Cell Carcinoma

  2006cited by this paper
• Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization.

  2006cited by this paper
• The Clinical Significance of Aurora-A/STK15/BTAK Expression in Human Esophageal Squamous Cell Carcinoma

  2005cited by this paper
• Copy number amplification of 3q26–27 oncogenes in microdissected oral squamous cell carcinoma and oral brushed samples from areca chewers

  2005cited by this paper
• RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

  2005cited by this paper
• Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

  2005cited by this paper
• Chfr is required for tumor suppression and Aurora A regulation

  2005cited by this paper
• The coordinate regulation of the p53 and mTOR pathways in cells.

  2005cited by this paper
• 1 BRCA 1 Phosphorylation by Aurora-A in the Regulation of G 2 to M Transition

  2004cited by this paper
• BRCA1 Phosphorylation by Aurora-A in the Regulation of G2 to M Transition*

  2004cited by this paper
• Aurora-A Kinase Regulates Telomerase Activity through c-Myc in Human Ovarian and Breast Epithelial Cells

  2004cited by this paper
• STK15/Aurora‐A expression in primary breast tumors is correlated with nuclear grade but not with prognosis

  2004cited by this paper
• Genome‐wide profiling of oral squamous cell carcinoma

  2004cited by this paper
• Overexpression and Amplification of Aurora-A in Hepatocellular Carcinoma

  2004cited by this paper
• Overexpression of Aurora-A Contributes to Malignant Development of Human Esophageal Squamous Cell Carcinoma

  2004cited by this paper
• Aurora-A Abrogation of p53 DNA Binding and Transactivation Activity by Phosphorylation of Serine 215*

  2004cited by this paper
• Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53

  2004cited by this paper
• AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol.

  2003cited by this paper
• Head and neck cancer

  2003cited by this paper
• Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells.

  2003cited by this paper
• Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters.

  2002cited by this paper
• The centrosome cycle

  2002cited by this paper
• The expression of Ki‐67, MCM3, and p27 defines distinct subsets of proliferating, resting, and differentiated cells

  2001cited by this paper
• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  2000cited by this paper
• CDDP induces p53-dependent apoptosis in tongue cancer cells.

  2000cited by this paper
• Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

  1998cited by this paper
• A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

  1998cited by this paper
• A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

  1997cited by this paper
• Head and neck cancer.

  1991cited by this paper

• Research progress on the relationship between AURKA and tumorigenesis: the neglected nuclear function of AURKA

  2024cites this paper
• Aurora Kinases as Therapeutic Targets in Head and Neck Cancer.

  2022cites this paper
• Association of Aurka Gene Polymorphism (RS2064863) with Oral Squamous Cell Carcinoma Development - An In Silico Study

  2020cites this paper
• Combined effect of genetic polymorphisms of AURKA and environmental factors on oral cancer development in Taiwan

  2017cites this paper
• The data of establishing a three-dimensional culture system for in vitro recapitulation and mechanism exploration of tumor satellite formation during cancer cell transition

  2017cites this paper
• The autophagic inhibition oral squamous cell carcinoma cancer growth of 16-hydroxy-cleroda-3,14-dine-15,16-olide

  2017cites this paper
• Molecular and cellular cues of diet-associated oral carcinogenesis--with an emphasis on areca-nut-induced oral cancer development.

  2015cites this paper
• Suppression of pro-inflammatory and pro-survival biomarkers in oral cancer patients consuming a black raspberry phytochemical-rich troche. Authors and Affiliations:

  2015influential citation
• AURKA Phe31Ile polymorphism interacted with use of alcohol, betel quid, and cigarettes at multiplicative risk of oral cancer occurrence

  2015cites this paper
• Role of Aurora-A in Ovarian Cancer: A Meta-Analysis

  2015cites this paper
• Suppression of Proinflammatory and Prosurvival Biomarkers in Oral Cancer Patients Consuming a Black Raspberry Phytochemical-Rich Troche

  2015influential citation
• Prognosis value of mitotic kinase Aurora-A for primary duodenal adenocarcinoma

  2014cites this paper
• EGF Up-Regulates miR-31 through the C/EBPβ Signal Cascade in Oral Carcinoma

  2014cites this paper
• Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior

  2014cites this paper
• Nupr1-Aurora Kinase A Pathway Provides Protection against Metabolic Stress-Mediated Autophagic-Associated Cell Death

  2012cites this paper
• Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy

  2012cites this paper
• Aurora‐A activation, correlated with hypoxia‐inducible factor‐1α, promotes radiochemoresistance and predicts poor outcome for nasopharyngeal carcinoma

  2012cites this paper
• The expression and significance of MRP1, LRP, TOPOIIβ, and BCL2 in tongue squamous cell carcinoma.

  2012cites this paper
• Composés de modulation de l'expression de l'aurora kinase a

  2011cites this paper
• The frequent co-expression of the oncogenes PIK3CA and PAK1 in oral carcinomas.

  2011cites this paper
• Proton HR-MAS MR spectroscopy of oral squamous cell carcinoma tissues: an ex vivo study to identify malignancy induced metabolic fingerprints

  2011cites this paper