Pharmacotherapy for hypertension in adults aged 18 to 59 years.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Cochrane Database of Systematic Reviews

• Publication date

  2017-08-16

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/14651858.CD008276.pub2PMID 28813123PMCID PMC6483466
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• First-line drugs for hypertension.

  2018cited by this paper
• Renin-angiotensin-aldosterone system blockers and cardiovascular outcomes: a meta-analysis of randomized clinical trials.

  2017cited by this paper
• Beta‐blockers for hypertension

  2017cited by this paper
• The effect of antihypertensive treatment on the incidence of stroke and cognitive decline in the elderly: a meta-analysis.

  2016cited by this paper
• Effects of blood pressure-lowering treatment. 6. Prevention of heart failure and new-onset heart failure – meta-analyses of randomized trials

  2016cited by this paper
• ACEIs/ARBs for the prevention of type 2 diabetes in patients with cardiovascular diseases: a systematic review and meta-analysis

  2016cited by this paper
• Effects of blood pressure reduction in mild hypertension: a systematic review and meta-analysis.

  2015cited by this paper
• Randomized controlled trials of blood pressure lowering in hypertension: a critical reappraisal.

  2015cited by this paper
• Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

  2014cited by this paper
• Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension.

  2014cited by this paper
• 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8).

  2014cited by this paper
• 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

  2013cited by this paper
• ESH / ESC Guidelines for the management of arterial hypertension

  2013cited by this paper
• Oslo Hypertension Study

  2012cited by this paper
• Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial

  2011cited by this paper
• Investigating strategies to improve attendance at screening visits in a randomized trial

  2011cited by this paper
• Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics

  2010cited by this paper
• Pharmacotherapy for hypertension in non‐elderly adults

  2010cited by this paper
• Efficacy and safety of nebivolol in Hispanics with stage I-II hypertension: a randomized placebo-controlled trial

  2010cited by this paper
• First-line drugs for hypertension.

  2009cited by this paper
• Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

  2009cited by this paper
• Long-Term Antihypertensive Efficacy and Safety of the Oral Direct Renin Inhibitor Aliskiren: A 12-Month Randomized, Double-Blind Comparator Trial With Hydrochlorothiazide

  2009cited by this paper
• Mild hypertension--early drug treatment or follow-up only? The Oslo study.

  2009cited by this paper
• Pharmacotherapy for hypertension in the elderly.

  2009cited by this paper
• Treatment of hypertension in patients 80 years of age or older.

  2008cited by this paper
• Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials

  2008cited by this paper
• Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial.

  2008cited by this paper
• Chapter 8: Assessing risk of bias in included studies

  2008cited by this paper
• Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.

  2007cited by this paper
• Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study.

  2007cited by this paper
• Beta-blockers for hypertension.

  2007cited by this paper
• Global burden of hypertension: analysis of worldwide data.

  2005cited by this paper
• Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials

  2005cited by this paper
• Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials.

  2005cited by this paper
• Apparent effect on blood pressure is only partly responsible for the risk reduction due to antihypertensive treatments

  2005cited by this paper
• How do thiazide and thiazide-like diuretics lower blood pressure?

  2004cited by this paper
• Grading quality of evidence and strength of recommendations

  2004cited by this paper
• A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension.

  2004cited by this paper
• Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.

  2003cited by this paper
• 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension

  2003cited by this paper
• Results of the pilot study for the Hypertension in the Very Elderly Trial

  2003cited by this paper
• Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials.

  2003cited by this paper
• The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial

  2003cited by this paper
• Diuretic Versus &agr;-Blocker as First-Step Antihypertensive Therapy: Final Results From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

  2003cited by this paper
• Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.

  2002cited by this paper
• The QUinapril Ischemic Event Trial (QUIET): evaluation of chronic ACE inhibitor therapy in patients with ischemic heart disease and preserved left ventricular function.

  2001cited by this paper
• Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.

  2001cited by this paper
• The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes.

  2001cited by this paper
• Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.

  2001cited by this paper
• Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study.

  2000cited by this paper
• Treatment of arterial hypertension with diuretics, beta- and calcium channel blockers in old patients

  2000cited by this paper
• Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators.

  2000cited by this paper
• Long-Term Effects of Cholesterol Lowering and Angiotensin-Converting Enzyme Inhibition on Coronary Atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT)

  2000cited by this paper
• Pharmacotherapy for hypertension in the elderly.

  2000cited by this paper
• Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.

  2000cited by this paper
• Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT).

  2000cited by this paper
• Efficacy of treating hypertension in women

  1999cited by this paper
• Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group.

  1999cited by this paper
• Study population and treatment titration in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT).

  1998cited by this paper
• Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39

  1998cited by this paper
• Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38

  1998cited by this paper
• Pharmacotherapy for hypertension in the elderly

  1998cited by this paper
• Clinical results of the Verapamil inHypertension and Atherosclerosis Study. VHAS Investigators.

  1997cited by this paper
• Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis.

  1997cited by this paper
• Clinical results of the Verapamil in Hypertension and Atherosclerosis Study

  1997cited by this paper
• Rationale and Design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

  1996cited by this paper
• Shanghai trial of nifedipine in the elderly (STONE).

  1996cited by this paper
• Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). ALLHAT Research Group.

  1996cited by this paper
• Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). A randomized controlled trial.

  1996cited by this paper
• New meta-analysis of treatment trials of hypertension: improving the estimate of therapeutic benefit.

  1996cited by this paper
• INSIGHT: international nifedipine GITS study intervention as a goal in hypertension treatment.

  1996cited by this paper
• Department of veterans Affairs single-drug therapy of hypertension study. Revised figures and new data. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.

  1995cited by this paper
• The Hypertension Optimal Treatment (HOT) Study: 12-month data on blood pressure and tolerability. With special reference to age and gender.

  1995cited by this paper
• Does antihypertensive treatment of the elderly prevent cardiovascular events or prolong life? A meta-analysis of hypertension treatment trials.

  1995cited by this paper
• INDANA: a meta-analysis on individual patient data in hypertension. Protocol and preliminary results.

  1995cited by this paper
• Lifestyle intervention: results of the Treatment of Mild Hypertension Study (TOMHS).

  1995cited by this paper
• Post-stroke antihypertensive treatment study. A preliminary result.

  1995cited by this paper
• A 12-month comparison of ACE inhibitor and CA antagonist therapy in mild to moderate essential hypertension--The GLANT Study. Study Group on Long-term Antihypertensive Therapy.

  1995cited by this paper
• Post-stroke antihypertensive treatment study. A preliminary result

  1995cited by this paper
• Long-term safety and efficacy of moexipril alone and in combination with hydrochlorothiazide in elderly patients with hypertension.

  1995cited by this paper
• Atenolol in Secondary Prevention after Stroke

  1995cited by this paper
• Systolic Hypertension in the Elderly: Long‐Term Lacidipine Treatment: Objective, Protocol, and Organization

  1994cited by this paper
• Treatment of elderly hypertensives in Japan: National Intervention Cooperative Study in Elderly Hypertensives. The National Intervention Cooperative Study Group.

  1994cited by this paper
• Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).

  1994cited by this paper
• Drug Treatment of Hypertension in the Elderly

  1994cited by this paper
• Hypertension in the elderly. Implications and generalizability of randomized trials.

  1994cited by this paper
• Drug treatment of hypertension in the elderly: a meta-analysis.

  1994cited by this paper
• Current Cardiovascular Drugs

  1993cited by this paper
• Single-Drug Therapy for Hypertension in Men -- A Comparison of Six Antihypertensive Agents with Placebo

  1993cited by this paper
• Trial of Secondary Prevention With Atenolol After Transient Ischemic Attack or Nondisabling Ischemic Stroke

  1993cited by this paper
• Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.

  1993cited by this paper
• STOP-Hypertension 2: a prospective intervention trial of "newer" versus "older" treatment alternatives in old patients with hypertension. Swedish Trial in Old Patients with Hypertension.

  1993cited by this paper
• The effects of blood pressure reduction in older patients: an overview of five randomized controlled trials in elderly hypertensives.

  1993cited by this paper
• A meta-analysis of outcome trials in elderly hypertensives.

  1992cited by this paper
• [Systolic hypertension in the elderly: Chinese trial (syst-China). Interim report].

  1992cited by this paper
• Medical Research Council trial of treatment of hypertension in older adults: principal results. MRC Working Party.

  1992cited by this paper
• Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)

  1991cited by this paper
• Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

  1991cited by this paper
• Syst-Eur. A multicentre trial on the treatment of isolated systolic hypertension in the elderly: Objectives, protocol, and organization

  1991cited by this paper
• The CASTEL project (CArdiovascular STudy in the ELderly): protocol, study design, and preliminary results of the initial survey.

  1991cited by this paper

• Target Trial Emulation of Beta‐Blockers After Diagnosis of Colorectal Polyps—Beneficial in Women

  2025cites this paper
• Pharmacotherapy for hypertension in adults 60 years or older.

  2025cites this paper
• Pharmacotherapy for mild hypertension.

  2025cites this paper
• Estimated pulse wave velocity as a potential predictor of albuminuria in hypertension

  2025cites this paper
• Vigorous physical activity does not lower all-cause and cardio-cerebrovascular mortality more than moderate physical activity in aged hypertensive patients

  2025cites this paper
• Association of the triglyceride-glucose series indices with hypertension and pre-hypertension in Anhui China

  2025cites this paper
• Efficacy and safety of intensive blood pressure control in patients over 60 years: A systematic review and meta-analysis

  2025cites this paper
• Evaluation of Bone–Implant Interface: Effects of Angiotensin II Receptor Blockade in Hypertensive Rats

  2025cites this paper
• A Comprehensive Review on Nanoparticles as Drug Delivery System and Their Role for Management of Hypertension.

  2024cites this paper
• ASSESSMENT OF SIMULATED SURGICAL DEXTERITY AFTER MODIFIABLE EXTERNAL EXPOSURES AMONG NOVICE VERSUS EXPERIENCED VITREORETINAL SURGEONS

  2024cites this paper
• Blood pressure control in patients aged above and below 75 years

  2024cites this paper
• Screening for hypertension in adults: protocol for evidence reviews to inform a Canadian Task Force on Preventive Health Care guideline update

  2024cites this paper
• The Role of Primary Care in Achieving Life’s Essential 8: A Scientific Statement From the American Heart Association

  2024cites this paper
• 2024 ESC Guidelines for the management of elevated blood pressure and hypertension.

  2024cites this paper
• Effects of physical activity on blood pressure and mortality among aged hypertensive patients: A cross-sectional study

  2024cites this paper
• Quality Control of Hydrochlorothiazide Pharmaceuticals

  2024cites this paper
• Diuretics use in the management of hypertension.

  2024cites this paper
• The effects of cereal β-glucans on cardiovascular risk factors and the role of the gut microbiome

  2024cites this paper
• Mechanism of wuweijiangyasan in the treatment of spontaneous hypertension based on network pharmacology

  2023cites this paper
• First-line diuretics versus other classes of antihypertensive drugs for hypertension.

  2023cites this paper
• Estrogen Deficiency Impairs Osseointegration in Hypertensive Rats Even Treated with Alendronate Coated on the Implant Surface

  2023cites this paper
• Impacts of increases and decreases of drugs on rehabilitation outcomes of subacute stroke patients.

  2023cites this paper
• Weight-adjusted caffeine and β-blocker use in novice versus senior retina surgeons: a self-controlled study of simulated performance

  2023cites this paper
• Blood pressure lowering effect of hydrochlorothiazide compared to other diuretics for hypertension

  2022cites this paper
• Prescribing patterns and pharmacoeconomic analysis of antihypertensive drugs in South Indian population: A cross-sectional study

  2022cites this paper
• Considerations for Optimal Blood Pressure Target of Hypertension

  2022cites this paper
• Diuretics versus others for long-term clinical outcomes as first-line antihypertensive medications: analysis of national real-world database

  2022cites this paper
• Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non‐hypertensive Alzheimer's patients

  2021cites this paper
• Hypertension in African Populations: Review and Computational Insights

  2021cites this paper
• Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

  2021cites this paper
• The Effect of Saffron Supplementation on Blood Pressure in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials

  2021cites this paper
• NHS Health Checks: an observational study of equity and outcomes 2009–2017

  2021cites this paper
• Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

  2021cites this paper
• Systematic Review of Self-Measured Blood Pressure Monitoring With Support: Intervention Effectiveness and Cost.

  2021cites this paper
• Effectiveness of Interventions to Enable Hypertension Medication Adherence in Low-And Middle-Income Countries: A Systematic Review and Meta-Analysis

  2021cites this paper
• The effect of cinnamon supplementation on blood pressure in adults: A systematic review and meta-analysis of randomized controlled trials.

  2020cites this paper
• Legacy effect of delayed blood pressure lowering drug treatment in middle-aged adults with mildly elevated blood pressure: systematic review and meta-analysis

  2020cites this paper
• Catestatin peptide of chromogranin A as a potential new target for several risk factors management in the course of metabolic syndrome.

  2020cites this paper
• Study on vascular mechanisms underlying the hypotensive effect of Sorghum halepense (L.) Pers.

  2020cites this paper
• Rates of delirium associated with calcium channel blockers compared to diuretics, renin-angiotensin system agents and beta-blockers: An electronic health records network study

  2020cites this paper
• Society of Behavioral Medicine position statement: Support the updated hypertension guidelines and modify Medicare Part B to improve hypertension management.

  2020cites this paper
• Prevalence of Hypertension, Treatment, and Blood Pressure Targets in Canada Associated With the 2017 American College of Cardiology and American Heart Association Blood Pressure Guidelines

  2019cites this paper
• Factors influencing hepatic metabolism of antihypertensive drugs: impact on clinical response

  2019cites this paper
• Postpartum Interventions to Reduce Long-Term Cardiovascular Disease Risk in Women After Hypertensive Disorders of Pregnancy: A Systematic Review

  2019cites this paper
• Risk-Benefit Assessment of Intense Blood Pressure Lowering.

  2019cites this paper
• Hypertension

  2019cites this paper
• Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis.

  2019cites this paper
• Risk of ESKD in Older Live Kidney Donors with Hypertension.

  2019cites this paper
• What is the first choice for blood pressure treatment?

  2019cites this paper
• Protective Effects of Nanoparticle-Loaded Aliskiren on Cardiovascular System in Spontaneously Hypertensive Rats

  2019cites this paper
• If You Change the Way You Look at Things, Things You Look at Change. Max Planck’s Challenge for Health, Health Care, and the Healthcare System

  2019cites this paper
• Pharmacotherapy for hypertension in adults 60 years or older.

  2019cites this paper
• Effect of the Single-Pill Amlodipine/Valsartan Combination on Hypertrophy and Myocardial Deformation Characteristics in Middle-Aged Patients with Essential Arterial Hypertension

  2019cites this paper
• Pharmacotherapy for hypertension in adults aged 18 to 59 years.

  2019cites this paper
• Effect of phosphodiesterase 5 inhibitors on blood pressure

  2019cites this paper
• Effects of 12-week brisk walking training on exercise blood pressure in elderly patients with essential hypertension: a pilot study

  2018cites this paper
• Central Noradrenergic Interactions with Alcohol and Regulation of Alcohol-Related Behaviors.

  2018cites this paper
• First-line drugs for hypertension.

  2018cites this paper
• The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review

  2018cites this paper
• Screening strategies for hypertension.

  2018cites this paper
• Sobrediagnóstico y sobretratamiento en el ámbito cardiovascular: factores de riesgo, no enfermedades

  2018cites this paper
• Pull-Strategien und das Apple-Prinzip

  2018cites this paper
• Is there RCT evidence to support the use of antihypertensive drugs over placebo/no treatment for primary prevention in adults with mild to moderate hypertension?

  2018cites this paper
• Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study

  2018cites this paper
• The pharmacological management of metabolic syndrome

  2018cites this paper
• Blood pressure is normal, but is the heart?

  2018cites this paper