Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Steroid Biochemistry and Molecular Biology

• Publication date

  2008-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.jsbmb.2008.01.002PMID 18304804PMCID PMC2699583
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Steroid receptor phosphorylation: a key modulator of multiple receptor functions.

  2007cited by this paper
• Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase.

  2007cited by this paper
• Determinants of Cell- and Gene-Specific Transcriptional Regulation by the Glucocorticoid Receptor

  2007cited by this paper
• Glucocorticoids: exemplars of multi‐tasking

  2006cited by this paper
• Chaperoning steroid hormone action.

  2006cited by this paper
• MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor.

  2006cited by this paper
• Expression and regulation of glucocorticoid receptor in human placental villous fibroblasts.

  2005cited by this paper
• Gene regulation by the glucocorticoid receptor: structure:function relationship.

  2005cited by this paper
• p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.

  2005cited by this paper
• Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.

  2004cited by this paper
• Modulation of Glucocorticoid Receptor Function via Phosphorylation

  2004cited by this paper
• Modulation of Glucocorticoid Receptor Transcriptional Activation, Phosphorylation, and Growth Inhibition by p27Kip1*

  2003cited by this paper
• Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

  2003cited by this paper
• The glucocorticoid receptor: coding a diversity of proteins and responses through a single gene.

  2002cited by this paper
• Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.

  2002cited by this paper
• Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

  2002cited by this paper
• Deciphering the Phosphorylation “Code” of the Glucocorticoid Receptor in Vivo * 210

  2002cited by this paper
• In vivo analysis of the model tyrosine aminotransferase gene reveals multiple sequential steps in glucocorticoid receptor action

  2001cited by this paper
• Transcriptional regulation of rat hepatic aryl sulfotransferase (SULT1A1) gene expression by glucocorticoids.

  2001cited by this paper
• Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase.

  1998cited by this paper
• Mouse Glucocorticoid Receptor Phosphorylation Status Influences Multiple Functions of the Receptor Protein*

  1997cited by this paper
• Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor

  1997cited by this paper
• Multilayered control of intracellular receptor function.

  1995cited by this paper
• Multilayered control of intracellular receptor function.

  1995cited by this paper
• Role of Acidic and Phosphorylated Residues in Gene Activation by the Glucocorticoid Receptor (*)

  1995cited by this paper
• Hormone-induced hyperphosphorylation of specific phosphorylated sites in the mouse glucocorticoid receptor.

  1995cited by this paper
• Identification of phosphorylated sites in the mouse glucocorticoid receptor.

  1991cited by this paper
• Two remote glucocorticoid responsive units interact cooperatively to promote glucocorticoid induction of rat tyrosine aminotransferase gene expression.

  1989cited by this paper
• Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity.

  1987cited by this paper
• Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.

  1970cited by this paper
• Tyrosine Aminotransferase: Enzyme Induction Independent of Adenosine 3',5'-Monophosphate

  1968cited by this paper

• Irisin regulates the phosphorylation of glucocorticoid receptor Ser212 and Ser234 and mediates glucocorticoid-induced muscle atrophy in mice

  2025cites this paper
• Glucocorticoid Insensitivity: Is It a Question of Time and Place?

  2025cites this paper
• The Glucocorticoid Receptor: Isoforms, Functions, and Contribution to Glucocorticoid Sensitivity

  2024cites this paper
• PI3K δ inhibition potentiates glucocorticoids in B-lymphoblastic leukemia by decreased receptor phosphorylation and enhanced gene regulation

  2023influential citation
• PI3Kδ Inhibition Potentiates Glucocorticoids in B-lymphoblastic Leukemia by Decreasing Receptor Phosphorylation and Enhancing Gene Regulation

  2023influential citation
• Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

  2023cites this paper
• Biased regulation of glucocorticoid receptors signaling.

  2023cites this paper
• REDD1 (regulated in development and DNA damage 1) modulates the glucocorticoid receptor function in keratinocytes

  2023cites this paper
• δ inhibition potentiates glucocorticoids in B-ALL by decreased receptor phosphorylation and enhanced gene regulation

  2023influential citation
• δ inhibition potentiates glucocorticoids in B-ALL by decreased receptor phosphorylation and enhanced gene regulation

  2023influential citation
• Research progress of glucocorticoid resistance in chronic rhinosinusitis with nasal polyps: A review

  2023cites this paper
• Genetically engineered mouse models of FK506‐binding protein 5

  2023cites this paper
• Crosstalk between p38 MAPK and GR Signaling

  2022influential citation
• Striatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling

  2022cites this paper
• Glucocorticoid Insensitivity in Asthma: The Unique Role for Airway Smooth Muscle Cells

  2022cites this paper
• Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

  2022cites this paper
• Sleep fragmentation engages stress-responsive circuitry, enhances inflammation and compromises hippocampal function following traumatic brain injury.

  2022cites this paper
• Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice.

  2022cites this paper
• Oxidative Stress Promotes Corticosteroid Insensitivity in Asthma and COPD

  2021cites this paper
• The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice

  2021cites this paper
• β-Ionone Attenuates Dexamethasone-Induced Suppression of Collagen and Hyaluronic Acid Synthesis in Human Dermal Fibroblasts

  2021cites this paper
• Lycii radicis cortex inhibits glucocorticoid-induced bone loss by downregulating Runx2 and BMP-2 expression

  2021cites this paper
• Allosteric binding on nuclear receptors: Insights on screening of non-competitive endocrine-disrupting chemicals.

  2021cites this paper
• Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.

  2021cites this paper
• Prostaglandin E2 stimulates cAMP signaling and re-sensitizes human leukemia cells to glucocorticoid-induced cell death.

  2020cites this paper
• Anti-inflammatory functions of the glucocorticoid receptor require DNA binding

  2020cites this paper
• Differential Phosphorylation of the Glucocorticoid Receptor in Hippocampal Subregions Induced by Contextual Fear Conditioning Training

  2020cites this paper
• Mitochondrial signaling in inflammation-induced depressive behavior in female and male rats: The role of glucocorticoid receptor.

  2019cites this paper
• Molecular mechanisms contributing to glucocorticoid resistance in lymphoid malignancies

  2019cites this paper
• The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus

  2019cites this paper
• The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor.

  2019cites this paper
• Estrogen Deficiency Promotes Hepatic Steatosis via a Glucocorticoid Receptor-Dependent Mechanism in Mice

  2018influential citation
• The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells

  2018cites this paper
• Nuclear Receptor Function through Genomics: Lessons from the Glucocorticoid Receptor.

  2017cites this paper
• The effect of environmental stress and selective glucocorticoid receptor modulators on chicken and human leukaemia cells

  2017cites this paper
• Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.

  2017cites this paper
• Checks and balances: The glucocorticoid receptor and NFĸB in good times and bad.

  2017cites this paper
• Analysis of drug resistance and the role of the stem cell niche in leukaemia

  2017influential citation
• Explorer The anti-inflammatory and immunosuppressive effects of glucocorticoids , recent developments and mechanistic insights

  2017cites this paper
• Distinct modifications of hippocampal glucocorticoid receptor phosphorylation and FKBPs by lipopolysaccharide in depressive female and male rats

  2017cites this paper
• Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia

  2017cites this paper
• Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor

  2017cites this paper
• A decline in female baboon hypothalamo-pituitary-adrenal axis activity anticipates aging

  2017cites this paper
• Male-specific effects of lipopolysaccharide on glucocorticoid receptor nuclear translocation in the prefrontal cortex of depressive rats

  2016cites this paper
• Lamin A/C Regulates Endothelial Glucocorticoid Receptor Nuclear Translocation in Response to Cyclic Stretch

  2016cites this paper
• Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept.

  2016cites this paper
• Glucocorticoid-independent modulation of GR activity: Implications for immunotherapy.

  2016cites this paper
• Development of mechanistic mathematical models for gene-mediated drug-drug interactions

  2016cites this paper
• Glucocorticoid therapy and ocular hypertension.

  2016cites this paper
• Vitamin D interferes with glucocorticoid responsiveness in human peripheral blood mononuclear target cells

  2016cites this paper
• The glucocorticoid receptor plays a central role in mammalian reproduction and signal integration in pituitary gonadotropes

  2015cites this paper
• Molecular mechanisms in the regulation of adult neurogenesis during stress

  2015cites this paper
• Hypoxia enhances glucocorticoid-induced apoptosis and cell cycle arrest via the PI3K/Akt signaling pathway in osteoblastic cells

  2015cites this paper
• Mechanisms involved in glucocorticoid induction of pituitary GH expression during embryonic development.

  2015cites this paper
• Fetal human airway smooth muscle cell production of leukocyte chemoattractants is differentially regulated by fluticasone

  2015cites this paper
• Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds.

  2015cites this paper
• Effects of Unpredictable Chronic Mild Stress on Adolescent Rats

  2014cites this paper
• Dominance of the strongest: inflammatory cytokines versus glucocorticoids.

  2014cites this paper
• Comprehensive overview of the structure and regulation of the glucocorticoid receptor.

  2014cites this paper
• Prenatal Alcohol Exposure Modifies Glucocorticoid Receptor Subcellular Distribution in the Medial Prefrontal Cortex and Impairs Frontal Cortex-Dependent Learning

  2014cites this paper
• Diabetogenic effects of Glucocorticoids : role of Protein Phosphatase 5 and GLP-1 receptor activation

  2014cites this paper
• Modulation of the Glucocorticoid Receptor Activity by Post-Translational Modifications

  2014cites this paper
• Analysis of glucocorticoid action in neural stem cells

  2014influential citation
• Caveolin-1 Regulates Genomic Action of the Glucocorticoid Receptor in Neural Stem Cells

  2014cites this paper
• The Interplay between the Glucocorticoid Receptor Activity and post-Translational Modifications in the Immune and Neuroendocrine Systems

  2014cites this paper
• Title: Caveolin-1 Regulates Genomic Action of the Glucocorticoid Receptor in Neural

  2014cites this paper
• Glucocorticoids: structure, signaling and molecular mechanisms in the treatment of diabetic retinopathy and diabetic macular edema.

  2014cites this paper
• Implications de la phosphatidylcholine phospholipase C, des transporteurs de dipeptides et de la cobalamine dans le processus inflammatoire. Application à l'étude de la mucoviscidose

  2013cites this paper
• The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease.

  2013cites this paper
• A preliminary evaluation of leukocyte phospho-glucocorticoid receptor as a potential biomarker of depressogenic vulnerability in healthy adults.

  2013cites this paper
• THE GLUCOCORTICOID RECEPTOR AS A REGULATOR OF CORTISOL RESPONSES IN CORTISOL RESISTANT PATIENTS AND HEALTHY SUBJECTS

  2013cites this paper
• Gender-specific effects of fluoxetine on hippocampal glucocorticoid receptor phosphorylation and behavior in chronically stressed rats.

  2013cites this paper
• Gender differences in CMS and the effects of antidepressant venlafaxine in rats.

  2013cites this paper
• Evaluation of Glucocorticoid Receptor Function in COPD Lung Macrophages Using Beclomethasone-17-Monopropionate

  2013cites this paper
• SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor

  2013cites this paper
• Phosphorylation of leukocyte glucocorticoid receptor in patients with current episode of major depressive disorder.

  2013cites this paper
• Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation

  2013cites this paper
• Phosphorylation: a fundamental regulator of steroid receptor action.

  2013cites this paper
• Transforming growth factor‐β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line

  2012cites this paper
• Effects of glucocorticoids on placental development and function : implications for fetal growth restriction

  2012cites this paper
• Folding of the glucocorticoid receptor N-terminal transactivation function: dynamics and regulation.

  2012cites this paper
• Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.

  2012cites this paper
• Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

  2012cites this paper
• The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes

  2012cites this paper
• Non-genomic actions of aldosterone: from receptors and signals to membrane targets.

  2012influential citation
• Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy.

  2012cites this paper
• of glucocorticoid-induced leucine zipper as a key regulator of tumor cell proliferation in epithelial ovarian cancer

  2012cites this paper
• ck2-Dependent Phosphorylation of Progesterone Receptors (PR) on Ser81 Regulates PR-B Isoform-Specific Target Gene Expression in Breast Cancer Cells

  2011cites this paper
• Glucocorticoid receptor and breast cancer

  2011influential citation
• Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

  2011cites this paper
• Ligand-Independent Phosphorylation of the Glucocorticoid Receptor Integrates Cellular Stress Pathways with Nuclear Receptor Signaling

  2011cites this paper
• The glucocorticoid receptor: pivot of depression and of antidepressant treatment?

  2011cites this paper
• Molecular basis for gene-specific transactivation by nuclear receptors.

  2011cites this paper
• Glucocorticoid receptor mutants: man-made tools for functional research.

  2011cites this paper
• Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-γ (PPARγ)*

  2011cites this paper
• Effects of Glucocorticoid on Microglia Cell Functions

  2011cites this paper
• Influence des hormones stéroïdes et potentiel préventif d'un antiprogestatif, l'ulpristal acétate, dans la tumorigenèse liée à la mutation du gène BRCA1

  2011cites this paper
• Sequence and Effects of Glucocorticoid Receptor Nuclear Retention; An Aid to Understanding Nuclear Retention in Other Proteins?

  2011cites this paper
• ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia

  2011influential citation
• Méthode de lyse cellulaire dans un tampon de réaction de rt-pcr

  2011cites this paper