Slow accumulation of mutations in Xpc-/- mice upon induction of oxidative stress.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  DNA Repair

• Publication date

  2013-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.dnarep.2013.08.019PMID 24084170PMCID PMC3847164
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Xeroderma pigmentosum

  2014cited by this paper
• Oxidative DNA Damage and Nucleotide Excision Repair

  2013cited by this paper
• Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.

  2013cited by this paper
• The cross talk between pathways in the repair of 8-oxo-7,8-dihydroguanine in mouse and human cells.

  2012cited by this paper
• Nrf1 CNC-bZIP Protein Promotes Cell Survival and Nucleotide Excision Repair through Maintaining Glutathione Homeostasis*

  2012cited by this paper
• Nucleotide excision repair–initiating proteins bind to oxidative DNA lesions in vivo

  2012cited by this paper
• The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells.

  2012influential reference
• XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species.

  2011cited by this paper
• The role of XPC: implications in cancer and oxidative DNA damage.

  2011cited by this paper
• Broad segmental progeroid changes in short-lived Ercc1−/Δ7 mice

  2011cited by this paper
• XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas.

  2011cited by this paper
• XPC silencing sensitizes glioma cells to arsenic trioxide via increased oxidative damage.

  2010cited by this paper
• Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions

  2010cited by this paper
• Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)]4

  2010cited by this paper
• Lipofuscin: detection and quantification by microscopic techniques.

  2010cited by this paper
• Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity

  2009cited by this paper
• The role of mitochondria in cholestatic liver injury.

  2009cited by this paper
• The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.

  2008cited by this paper
• Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.

  2008cited by this paper
• Dissection of the Molecular Defects Caused by Pathogenic Mutations in the DNA Repair Factor XPC

  2008cited by this paper
• Oxidative DNA damage in XPC-knockout and its wild mice treated with equine estrogen.

  2008cited by this paper
• Bulky DNA lesions induced by reactive oxygen species.

  2008cited by this paper
• Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts.

  2007cited by this paper
• The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum.

  2007cited by this paper
• DNA Repair and Mutagenesis

  2006cited by this paper
• New functions of XPC in the protection of human skin cells from oxidative damage

  2006cited by this paper
• Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.

  2005cited by this paper
• Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis.

  2005cited by this paper
• Functional characterization of global genomic DNA repair and its implications for cancer.

  2003cited by this paper
• Xeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylase

  2003cited by this paper
• Assessment of Carcinogenicity of Di(2-ethylhexyl phthalate in a Short-Term Assay Using Xpa-/- and Xpa-/ - /p53+/-Mice

  2002cited by this paper
• DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice.

  2001cited by this paper
• Chronic toxicity of di(2-ethylhexyl)phthalate in mice.

  2000cited by this paper
• Chronic toxicity of di(2-ethylhexyl)phthalate in rats.

  2000cited by this paper
• The Oxidative DNA Lesion 8,5′-(S)-Cyclo-2′-deoxyadenosine Is Repaired by the Nucleotide Excision Repair Pathway and Blocks Gene Expression in Mammalian Cells*

  2000cited by this paper
• p53 mutations in skin and internal tumors of xeroderma pigmentosum patients belonging to the complementation group C.

  1998cited by this paper
• Characterization of defective nucleotide excision repair in XPC mutant mice.

  1997cited by this paper
• Sunlight and skin cancer: another link revealed.

  1997cited by this paper
• Rapid accumulation of genome rearrangements in liver but not in brain of old mice

  1997cited by this paper
• Structural origins of bulky oxidative DNA adducts (type II I-compounds) as deduced by oxidation of oligonucleotides of known sequence.

  1996cited by this paper
• Xpa knockout mice.

  1996cited by this paper
• Xpa knockout mice.

  1996cited by this paper
• Lipofuscin as an indicator of oxidative stress and aging.

  1989cited by this paper
• Lipofuscin as an indicator of oxidative stress and aging.

  1989cited by this paper
• Xeroderma Pigmentosum: Cutaneous, Ocular, and Neurologic Abnormalities in 830 Published Cases

  1987cited by this paper
• DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum.

  1984cited by this paper

• UVA-light-induced mutagenesis in the exome of human nucleotide excision repair-deficient cells

  2025cites this paper
• Cigarette Smoke and Decreased DNA Repair by Xeroderma Pigmentosum Group C Use a Double Hit Mechanism for Epithelial Cell Lung Carcinogenesis

  2025cites this paper
• Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis

  2025cites this paper
• XPC Protects against Carcinogen-Induced Histologic Progression to Lung Squamous Cell Carcinoma by Reduced Basal Epithelial Cell Proliferation

  2024cites this paper
• The mutagenic consequences of defective DNA repair.

  2024cites this paper
• Can accelerated ageing models inform us on age‐related tauopathies?

  2023cites this paper
• Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

  2022cites this paper
• Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study

  2021cites this paper
• Genomic alterations and abnormal expression of APE2 in multiple cancers

  2020cites this paper
• XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature

  2020cites this paper
• The impact of oxidative stress damage induced by the environmental stressors on COVID-19

  2020cites this paper
• Xeroderma Pigmentosum C (XPC) Mutations in Primary Fibroblasts Impair Base Excision Repair Pathway and Increase Oxidative DNA Damage

  2020influential citation
• DNA repair as an emerging target for COPD-lung cancer overlap.

  2019cites this paper
• XPC protects against smoking- and carcinogen-induced lung adenocarcinoma.

  2019influential citation
• Environmentally relevant exposure to dibutyl phthalate disrupts DNA damage repair gene expression in the mouse ovary†

  2019cites this paper
• The impact of oxidative DNA damage and stress on telomere homeostasis.

  2019cites this paper
• XPC beyond nucleotide excision repair and skin cancers.

  2019cites this paper
• XPD/ERCC2 mutations interfere in cellular responses to oxidative stress.

  2019cites this paper
• Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation

  2018cites this paper
• UVA, metabolism and melanoma: UVA makes melanoma hungry for metastasis

  2018cites this paper
• Dramatic response to nivolumab in xeroderma pigmentosum skin tumor

  2018cites this paper
• Altered vulnerability to asthma at various levels of ambient Benzo[a]Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms.

  2017cites this paper
• Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development

  2017cites this paper
• The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression

  2017cites this paper
• Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics.

  2016cites this paper
• Schizophrenia: A critical view on genetic effects

  2016cites this paper
• Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes.

  2016cites this paper
• Ultra-flexible nanocarriers for enhanced topical delivery of a highly lipophilic antioxidative molecule for skin cancer chemoprevention.

  2016cites this paper
• XPC deficiency is related to APE1 and OGG1 expression and function.

  2016cites this paper
• Premature skin aging features rescued by inhibition of NADPH oxidase activity in XPC-deficient mice.

  2015cites this paper
• Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

  2015cites this paper
• Role of oxidative and energy metabolism in skin aging and UV-B induced carcinogenesis

  2015cites this paper
• Enhanced Percutaneous Delivery of 1,1-bis(3'-indolyl)-1-(p-chlorophenyl) Methane for Skin Cancer Chemoprevention.

  2015cites this paper
• Oxidative and energy metabolism as potential clues for clinical heterogeneity in nucleotide excision repair disorders.

  2015cites this paper
• An altered redox balance and increased genetic instability characterize primary fibroblasts derived from xeroderma pigmentosum group A patients.

  2015cites this paper
• A Closer Look at Papillary Thyroid Carcinoma

  2015cites this paper
• Xeroderma pigmentosum complementation group C protein (XPC) expression in basal cell carcinoma.

  2015cites this paper
• XPC: Going where no DNA damage sensor has gone before.

  2015cites this paper
• In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals

  2014cites this paper
• The sensitivity of young animals to benzo[a]pyrene-induced genotoxic stress

  2014cites this paper
• Etude du facteur de réparation de l’ADN, Xeroderma pigmentosum du groupe C (XPC), dans les cellules souches hématopoïétiques

  2014cites this paper
• Exposure to genotoxic carcinogens at young age: experimental studies to assess children's susceptibility to mutagenic effects of environmental chemicals

  2014cites this paper
• Attenuated NER Expressions of XPF and XPC Associated with Smoking Are Involved in the Recurrence of Bladder Cancer

  2014cites this paper
• The DNA damage response: nucleic acid regulation in sequence

  2014cites this paper
• Aging on a different scale – chronological versus pathology-related aging

  2013cites this paper
• UvA-DARE (Digital Academic Repository) Aging on a different scale - chronological versus pathology-related aging

  year unknowncites this paper