Gibberellin-deactivating GA2OX enzymes act as a hub for auxin–gibberellin cross talk in Arabidopsis thaliana root growth regulation

Significance Plant growth and development depend on the precise regulation of cell elongation. The phytohormone gibberellin promotes cell elongation, while elevated auxin levels inhibit root growth. This study reveals that auxin regulates gibberellin levels in Arabidopsis thaliana roots by controlling the expression of GA2OX6 and GA2OX8 genes, which inactivate gibberellins, thereby limiting cell elongation. GA2OX genes act as integrators of gibberellin and auxin signaling. By elucidating this interaction, the study advances our understanding of the mechanisms underlying root growth regulation in plants.

• Publication year

  2025

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2025-07-22

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1073/pnas.2425574122PMID 40694327PMCID 12318176
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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