The Cardiohepatic Axis in Cirrhosis

Central Illustration

• Publication year

  2025

• Venue

  JACC: Basic to Translational Science

• Publication date

  2025-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jacbts.2025.101314PMID 40738513PMCID 12434259
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cardiac dysfunction in patients with cirrhosis and acute decompensation

  2024cited by this paper
• Therapies for Cirrhotic Cardiomyopathy: Current Perspectives and Future Possibilities

  2024cited by this paper
• Update on cirrhotic cardiomyopathy: from etiopathogenesis to treatment

  2024cited by this paper
• Reply to: Correspondence on “Cardiomyopathy in cirrhosis: From pathophysiology to clinical care”

  2024cited by this paper
• Role of Galectin in Cardiovascular Conditions including Cirrhotic Cardiomyopathy

  2023cited by this paper
• Cardiomyopathy in cirrhosis: From pathophysiology to clinical care

  2023cited by this paper
• Cirrhotic cardiomyopathy: Pathogenesis, clinical features, diagnosis, treatment and prognosis.

  2023cited by this paper
• Left atrial strain and ventricular global longitudinal strain in cirrhotic patients using the new criteria of Cirrhotic Cardiomyopathy Consortium

  2023cited by this paper
• Assessment of Vascular and Valvular Calcification Improves Screening for Coronary Artery Disease Before Liver Transplantation.

  2023cited by this paper
• Assessment of Post-systolic Shortening and Global Longitudinal Strain Improves the Sensitivity of Dobutamine Stress Echocardiography in End Stage Liver Disease.

  2023cited by this paper
• Prevalence of Cardiac Dysfunction in Cirrhosis and Its Relation With Meld Score

  2022cited by this paper
• Echocardiographic assessment of cardiovascular function and clinical outcomes in liver transplant recipients

  2022cited by this paper
• Serum troponin is elevated in acute decompensation and acute-on-chronic liver failure and is associated with severity of liver disease and short-term mortality

  2022cited by this paper
• Cirrhotic cardiomyopathy: Appraisal of the original and revised criteria in predicting posttransplant cardiac outcomes

  2022cited by this paper
• Outcomes of Liver Transplantation in Patients With Preexisting Coronary Artery Disease

  2022cited by this paper
• Myocardial strain: a clinical review

  2022cited by this paper
• Cardiovascular manifestation of end-stage liver disease and perioperative echocardiography for liver transplantation: anesthesiologist’s view

  2022cited by this paper
• Evaluation of subclinical ventricular systolic dysfunction assessed using global longitudinal strain in liver cirrhosis: A systematic review, meta-analysis, and meta-regression

  2022cited by this paper
• Review article: comprehensive analysis of cirrhotic cardiomyopathy

  2021cited by this paper
• Current Concepts of Cirrhotic Cardiomyopathy.

  2021cited by this paper
• Correlation of global longitudinal strain with disease severity in liver cirrhosis

  2021cited by this paper
• Cardiovascular magnetic resonance demonstrates structural cardiac changes following transjugular intrahepatic portosystemic shunt

  2021cited by this paper
• Mechanistic insights into the pathophysiology of cirrhotic cardiomyopathy.

  2021cited by this paper
• Diastolic Dysfunction Is a Predictor of Poor Survival in Patients with Decompensated Cirrhosis

  2021cited by this paper
• Cirrhotic Cardiomyopathy Predicts Posttransplant Cardiovascular Disease: Revelations of the New Diagnostic Criteria

  2021cited by this paper
• Cirrhotic portal hypertension: From pathophysiology to novel therapeutics

  2020cited by this paper
• Prognostic Value of B‐Type Natriuretic Peptide in Liver Transplant Patients: Implication in Posttransplant Mortality

  2020cited by this paper
• Myocardial structural and functional changes in patients with liver cirrhosis awaiting liver transplantation: a comprehensive cardiovascular magnetic resonance and echocardiographic study

  2020cited by this paper
• Value of Speckle Tracking-Based Deformation Analysis in Screening Relatives of Patients Asymptomatic Dilated Cardiomyopathy.

  2020cited by this paper
• Fibrogenesis and inflammation contribute to the pathogenesis of cirrhotic cardiomyopathy

  2020cited by this paper
• Nonalcoholic Steatohepatitis is the Most Rapidly Increasing Indication for Liver Transplantation in the United States.

  2020cited by this paper
• Global Longitudinal Strain at Rest as an Independent Predictor of Mortality in Liver Transplant Candidates: A Retrospective Clinical Study

  2020cited by this paper
• Protective Effects of Spermidine Against Cirrhotic Cardiomyopathy in Bile Duct-Ligated Rats.

  2020cited by this paper
• Impact of cardiac function, refractory ascites and beta blockers on the outcome of patients with cirrhosis listed for liver transplantation.

  2020cited by this paper
• Echocardiographic abnormalities in patients with cirrhosis and relation to disease severity

  2019cited by this paper
• Left Ventricular Longitudinal Contractility Predicts Acute‐on‐Chronic Liver Failure Development and Mortality After Transjugular Intrahepatic Portosystemic Shunt

  2019cited by this paper
• Myocardial extracellular volume quantified by magnetic resonance is increased in cirrhosis and related to poor outcome

  2018cited by this paper
• Cardiac MRI T2* in Liver Transplant Candidates: Application and Performance of a Novel Imaging Technique to Identify Patients at Risk for Poor Posttransplant Cardiac Outcomes

  2018cited by this paper
• &bgr;-Blocker therapy for cirrhotic cardiomyopathy: a randomized-controlled trial

  2018cited by this paper
• Elevated cardiac troponin T in cirrhotic patients with emergency care admissions: Associations with mortality

  2018cited by this paper
• Assessment of Left Ventricular Function by Echocardiography: The Case for Routinely Adding Global Longitudinal Strain to Ejection Fraction.

  2018cited by this paper
• Multidisciplinary approach to cardiac and pulmonary vascular disease risk assessment in liver transplantation: An evaluation of the evidence and consensus recommendations

  2018cited by this paper
• Prognostic value of short-term follow-up BNP in hospitalized patients with heart failure

  2017cited by this paper
• Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart

  2017cited by this paper
• Transjugular intrahepatic portosystemic shunt: impact on systemic haemodynamics and renal and cardiac function in patients with cirrhosis

  2017cited by this paper
• A Test in Context: E/A and E/e' to Assess Diastolic Dysfunction and LV Filling Pressure.

  2017cited by this paper
• Diastolic dysfunction in cirrhosis

  2016cited by this paper
• Brain Natriuretic Peptide in Liver Cirrhosis and Fatty Liver: Correlation with Cardiac Performance

  2016cited by this paper
• Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.

  2016cited by this paper
• Left Ventricular Myocardial Mechanics in Cirrhosis: A Speckle Tracking Echocardiographic Study

  2016cited by this paper
• T1 Mapping in Characterizing Myocardial Disease: A Comprehensive Review.

  2016cited by this paper
• Prevalence and impact on survival of hepatopulmonary syndrome and cirrhotic cardiomyopathy in a cohort of cirrhotic patients

  2015cited by this paper
• Assessing Contractile Function When Ejection Fraction Is Normal: A Case for Strain Imaging.

  2015cited by this paper
• Cirrhotic cardiomyopathy: a cardiologist's perspective.

  2014cited by this paper
• Liver cirrhosis.

  2014cited by this paper
• Pre-transplant Left Ventricular Diastolic Dysfunction Is Associated with Post Transplant Acute Graft Rejection and Graft Failure

  2014cited by this paper
• Exercise standards for testing and training: a scientific statement from the American Heart Association.

  2013cited by this paper
• Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012

  2013cited by this paper
• Galectin-3 and Cardiac Function in Survivors of Acute Myocardial Infarction

  2013cited by this paper
• Cardiac Disease Evaluation and Management Among Kidney and Liver Transplantation Candidates: A Scientific Statement From the American Heart Association and the American College of Cardiology Foundation

  2012cited by this paper
• Diastolic Dysfunction in Patients With End-Stage Liver Disease is Associated With Development of Heart Failure Early After Liver Transplantation

  2012cited by this paper
• Cardiac disease evaluation and management among kidney and liver transplantation candidates: a scientific statement from the American Heart Association and the American College of Cardiology Foundation: endorsed by the American Society of Transplant Surgeons, American Society of Transplantation, and

  2012cited by this paper
• Patients transplanted for nonalcoholic steatohepatitis are at increased risk for postoperative cardiovascular events

  2012cited by this paper
• Diastolic dysfunction in patients with end-stage liver disease is associated with development of heart failure early after liver transplantation.

  2011cited by this paper
• Comparison of the frequency of coronary artery disease in alcohol-related versus non-alcohol-related endstage liver disease.

  2011cited by this paper
• Coronary multidetector computed tomographic angiography to evaluate coronary artery disease in liver transplant candidates: methods, feasibility and initial experience

  2011cited by this paper
• Role of cardiac myofilament proteins titin and collagen in the pathogenesis of diastolic dysfunction in cirrhotic rats.

  2011cited by this paper
• High brain‐natriuretic peptide level predicts cirrhotic cardiomyopathy in liver transplant patients

  2011cited by this paper
• On T2* Magnetic Resonance and Cardiac Iron

  2011cited by this paper
• Diastolic tissue Doppler indexes correlate with the degree of collagen expression and cross-linking in heart failure and normal ejection fraction.

  2011cited by this paper
• Predictors of cardiovascular events after liver transplantation: A role for pretransplant serum troponin levels

  2011cited by this paper
• Hepatic and cardiac iron overload among patients with end‐stage liver disease referred for liver transplantation

  2010cited by this paper
• Cirrhotic cardiomyopathy.

  2010cited by this paper
• Galectin‐3, cardiac structure and function, and long‐term mortality in patients with acutely decompensated heart failure

  2010cited by this paper
• Myocardial late gadolinium enhancement cardiovascular magnetic resonance in patients with cirrhosis

  2010cited by this paper
• Low cardiac output predicts development of hepatorenal syndrome and survival in patients with cirrhosis and ascites

  2009cited by this paper
• Preoperative dobutamine stress echocardiographic findings and subsequent short‐term adverse cardiac events after orthotopic liver transplantation

  2008cited by this paper
• Prevalence of coronary artery calcification in patients undergoing assessment for orthotopic liver transplantation

  2008cited by this paper
• QT Interval Correction in Patients with Cirrhosis

  2007cited by this paper
• Cardiac hemodynamic and coronary angiographic characteristics of patients being evaluated for liver transplantation.

  2006cited by this paper
• Current perspectives in diastolic dysfunction and diastolic heart failure

  2006cited by this paper
• Cardiac, Neuroadrenergic, and Portal Hemodynamic Effects of Prolonged Aldosterone Blockade in Postviral Child A Cirrhosis

  2005cited by this paper
• LIVER FAILURE AND LIVER DISEASE

  2005cited by this paper
• Altered Titin Expression, Myocardial Stiffness, and Left Ventricular Function in Patients With Dilated Cardiomyopathy

  2004cited by this paper
• Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis

  2003cited by this paper
• QT interval in patients with non-cirrhotic portal hypertension and in cirrhotic patients treated with transjugular intrahepatic porto-systemic shunt.

  2003cited by this paper
• Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis.

  2003cited by this paper
• Prolongation of QTc interval: relationship with etiology and severity of liver disease, mortality and liver transplantation

  2003cited by this paper
• Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis

  2002cited by this paper
• The cardiac response to exercise in cirrhosis

  2001cited by this paper
• Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis

  2001cited by this paper
• Cardiac excitation-contraction coupling in the portal hypertensive rat.

  2000cited by this paper
• Elevated circulating cardiac troponin I in patients with cirrhosis

  1999cited by this paper
• Q‐T interval prolongation in cirrhosis: Prevalence, relationship with severity, and etiology of the disease and possible pathogenetic factors

  1998cited by this paper
• Post-liver transplantation myocardial dysfunction.

  1998cited by this paper
• Potassium currents in atrial and ventricular myocytes from a rat model of cirrhosis.

  1997cited by this paper
• The prevalence of coronary artery disease in liver transplant candidates over age 50.

  1995cited by this paper
• Left ventricular measurements with cine and spin-echo MR imaging: a study of reproducibility with variance component analysis.

  1993cited by this paper
• Signal Transduction by G Proteins in Cardiac Tissues

  1992cited by this paper
• Reduced cardiovascular responsiveness to exercise-induced sympathoadrenergic stimulation in patients with cirrhosis.

  1991cited by this paper

• Liver Fibrosis and Sudden Cardiac Arrest: A Prospective Cohort Study of 452,454 Individuals.

  2026cites this paper
• The Heart-Brain-Metabolism Axis in Cardiovascular and Neurologic Disease.

  2025cites this paper