During early differentiation of T helper cells, stochastic cytokine expression triggers the co-expression of antagonistic transcription factors at high levels, buffered by the interplay between extracellular and intracellular signaling components.
Stochastic Cytokine Expression Induces Mixed T Helper Cell States
Miaoqing Fang,Huangming Xie,S. Dougan,H. Ploegh,A. van Oudenaarden
Published 2013 in PLoS Biology
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- Publication year
2013
- Venue
PLoS Biology
- Publication date
2013-07-01
- Fields of study
Biology, Medicine
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Semantic Scholar, PubMed
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