Yersinia type III effectors perturb host innate immune responses.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  World Journal of Biological Chemsitry

• Publication date

  2016-02-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4331/wjbc.v7.i1.1PMID 26981193PMCID PMC4768113
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Current activities of the Yersinia effector protein YopM.

  2015cited by this paper
• Yersinia protein kinase A phosphorylates vasodilator‐stimulated phosphoprotein to modify the host cytoskeleton

  2015cited by this paper
• Necroptosis and its role in inflammation

  2015cited by this paper
• Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague

  2015cited by this paper
• Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization

  2015cited by this paper
• Integrin-Mediated First Signal for Inflammasome Activation in Intestinal Epithelial Cells

  2014cited by this paper
• Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

  2014cited by this paper
• IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM

  2014cited by this paper
• Caspase-3 Mediates the Pathogenic Effect of Yersinia pestis YopM in Liver of C57BL/6 Mice and Contributes to YopM's Function in Spleen

  2014cited by this paper
• Are Reactive Oxygen Species Always Detrimental to Pathogens?

  2014cited by this paper
• Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

  2014cited by this paper
• Regulation of Yersinia Protein Kinase A (YpkA) Kinase Activity by Multisite Autophosphorylation and Identification of an N-terminal Substrate-binding Domain in YpkA*

  2014cited by this paper
• Recognition of bacteria by inflammasomes.

  2013cited by this paper
• Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors

  2013cited by this paper
• Yersinia infection tools—characterization of structure and function of adhesins

  2013cited by this paper
• Mammalian phospholipase C.

  2013cited by this paper
• Yersinia pseudotuberculosis Efficiently Escapes Polymorphonuclear Neutrophils during Early Infection

  2013cited by this paper
• Murine Neonates Infected with Yersinia enterocolitica Develop Rapid and Robust Proinflammatory Responses in Intestinal Lymphoid Tissues

  2013cited by this paper
• Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection.

  2013cited by this paper
• Yersinia enterocolitica inactivates NK cells.

  2013cited by this paper
• Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides

  2013cited by this paper
• Interleukin-10 Induction Is an Important Virulence Function of the Yersinia pseudotuberculosis Type III Effector YopM

  2012cited by this paper
• YopJ-Induced Caspase-1 Activation in Yersinia-Infected Macrophages: Independent of Apoptosis, Linked to Necrosis, Dispensable for Innate Host Defense

  2012cited by this paper
• Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling

  2012cited by this paper
• The NLRP12 inflammasome recognizes Yersinia pestis.

  2012cited by this paper
• Eukaryotic Initiation Factor 2 (eIF2) Signaling Regulates Proinflammatory Cytokine Expression and Bacterial Invasion*

  2012cited by this paper
• Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction.

  2012cited by this paper
• The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing.

  2012cited by this paper
• ErratumThe NLRP12 Inflammasome Recognizes Yersinia pestis

  2012cited by this paper
• Yersinia enterocolitica YopT and Clostridium difficile Toxin B Induce Expression of GILZ in Epithelial Cells

  2012cited by this paper
• A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages

  2011cited by this paper
• In vitro activation of murine peritoneal macrophages by recombinant YopJ: production of nitric oxide, proinflammatory cytokines and chemokines.

  2011cited by this paper
• Recombinant YopJ induces apoptotic cell death in macrophages through TLR2.

  2011cited by this paper
• NF-κB signaling pathways regulated by CARMA family of scaffold proteins

  2011cited by this paper
• Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.

  2011cited by this paper
• Type III Secretion System-Dependent Translocation of Ectopically Expressed Yop Effectors into Macrophages by Intracellular Yersinia pseudotuberculosis

  2011cited by this paper
• Mitogen-Activated Protein Kinase-Dependent Interleukin-1α Intracrine Signaling Is Modulated by YopP during Yersinia enterocolitica Infection

  2011cited by this paper
• Neutrophils Are Resistant to Yersinia YopJ/P-Induced Apoptosis and Are Protected from ROS-Mediated Cell Death by the Type III Secretion System

  2010cited by this paper
• Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 Production and Virulence

  2010cited by this paper
• YopJ-Promoted Cytotoxicity and Systemic Colonization Are Associated with High Levels of Murine Interleukin-18, Gamma Interferon, and Neutrophils in a Live Vaccine Model of Yersinia pseudotuberculosis Infection

  2010cited by this paper
• YopH inhibits early pro-inflammatory cytokine responses during plague pneumonia

  2010cited by this paper
• Yersinia Virulence Factor YopM Induces Sustained RSK Activation by Interfering with Dephosphorylation

  2010cited by this paper
• A newly identified bacterial cell-penetrating peptide that reduces the transcription of pro-inflammatory cytokines

  2010cited by this paper
• ROS‐inhibitory activity of YopE is required for full virulence of Yersinia in mice

  2010cited by this paper
• Bacterial Toxins Induce Sustained mRNA Expression of the Silencing Transcription Factor klf2 via Inactivation of RhoA and Rhophilin 1

  2009cited by this paper
• Characterization of New Substrates Targeted By Yersinia Tyrosine Phosphatase YopH

  2009cited by this paper
• Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway.

  2009cited by this paper
• Yersinia pseudotuberculosis Virulence Determinants Invasin, YopE, and YopT Modulate RhoG Activity and Localization

  2009cited by this paper
• Gr1+ Cells Control Growth of YopM-Negative Yersinia pestis during Systemic Plague

  2009cited by this paper
• Sequestering of Rac by the Yersinia Effector YopO Blocks Fcγ Receptor-mediated Phagocytosis*

  2009cited by this paper
• Yersinia enterocolitica differentially modulates RhoG activity in host cells

  2009cited by this paper
• Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity.

  2009cited by this paper
• Cell type‐specific effects of Yersinia pseudotuberculosis virulence effectors

  2009cited by this paper
• The polybasic region of Rho GTPases defines the cleavage by Yersinia enterocolitica outer protein T (YopT)

  2008cited by this paper
• Reduced Secretion of YopJ by Yersinia Limits In Vivo Cell Death but Enhances Bacterial Virulence

  2008cited by this paper
• Differential roles of Yersinia outer protein P-mediated inhibition of nuclear factor-kappa B in the induction of cell death in dendritic cells and macrophages.

  2008cited by this paper
• Molecular mechanisms of phagocytic uptake in mammalian cells

  2008cited by this paper
• IL-10: The Master Regulator of Immunity to Infection

  2008cited by this paper
• Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ

  2008cited by this paper
• Yersinia Protein Kinase YopO Is Activated by A Novel G-actin Binding Process*

  2007cited by this paper
• YopJ targets TRAF proteins to inhibit TLR‐mediated NF‐κB, MAPK and IRF3 signal transduction

  2007cited by this paper
• Identification of a molecular target for the Yersinia protein kinase A.

  2007cited by this paper
• Yersinia outer proteins E, H, P, and T differentially target the cytoskeleton and inhibit phagocytic capacity of dendritic cells.

  2007cited by this paper
• Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells

  2007cited by this paper
• The Yersinia Effector Protein YpkA Induces Apoptosis Independently of Actin Depolymerization1

  2007cited by this paper
• Yersinia virulence depends on mimicry of host Rho-family nucleotide dissociation inhibitors.

  2006cited by this paper
• Yersinia YopJ Acetylates and Inhibits Kinase Activation by Blocking Phosphorylation

  2006cited by this paper
• Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling.

  2006cited by this paper
• RhoG Regulates the Neutrophil NADPH Oxidase1

  2006cited by this paper
• Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling

  2006cited by this paper
• Functional analysis of the YopE GTPase‐activating protein (GAP) activity of Yersinia pseudotuberculosis

  2006cited by this paper
• RhoG Regulates the Neutrophil NADPH Oxidase

  2006cited by this paper
• Yersinia pestis YopJ Suppresses Tumor Necrosis Factor Alpha Induction and Contributes to Apoptosis of Immune Cells in the Lymph Node but Is Not Required for Virulence in a Rat Model of Bubonic Plague

  2006cited by this paper
• The discovery of SycO highlights a new function for type III secretion effector chaperones

  2006cited by this paper
• Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection

  2006cited by this paper
• The Ser/Thr kinase activity of the Yersinia protein kinase A (YpkA) is necessary for full virulence in the mouse, mollifying phagocytes, and disrupting the eukaryotic cytoskeleton.

  2006cited by this paper
• Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes.

  2006cited by this paper
• Interaction of Yersinia pestis with Macrophages: Limitations in YopJ-Dependent Apoptosis

  2006cited by this paper
• YopM of Yersinia enterocolitica specifically interacts with alpha1-antitrypsin without affecting the anti-protease activity.

  2006cited by this paper
• The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling.

  2006cited by this paper
• Absence of Toll-Like Receptor 4 Signaling Results in Delayed Yersinia enterocolitica YopP-Induced Cell Death of Dendritic Cells

  2006cited by this paper
• Cellular mechanisms of bacterial internalization counteracted by Yersinia.

  2005cited by this paper
• Overview of cell death signaling pathways

  2005cited by this paper
• Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation

  2005cited by this paper
• Inhibition of MAPK and NF-κB Pathways Is Necessary for Rapid Apoptosis in Macrophages Infected with Yersinia1

  2005cited by this paper
• Functions of the Yersinia effector proteins in inhibiting host immune responses.

  2005cited by this paper
• Mammalian G proteins and their cell type specific functions.

  2005cited by this paper
• The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation

  2005cited by this paper
• Identification of a nuclear targeting signal in YopM from Yersinia spp.

  2004cited by this paper
• Transcriptional responses of murine macrophages to infection with Yersinia enterocolitica

  2004cited by this paper
• Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles1

  2004cited by this paper
• Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells.

  2004cited by this paper
• Lck Dephosphorylation at Tyr-394 and Inhibition of T Cell Antigen Receptor Signaling by Yersinia Phosphatase YopH*

  2004cited by this paper
• The Plague Virulence Protein YopM Targets the Innate Immune Response by Causing a Global Depletion of NK Cells

  2004cited by this paper
• Targeting Rac1 by the Yersinia Effector Protein YopE Inhibits Caspase-1-mediated Maturation and Release of Interleukin-1β*

  2004cited by this paper
• Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica †

  2004cited by this paper
• Type III protein secretion mechanism in mammalian and plant pathogens.

  2004cited by this paper
• Role of Toll-Like Receptor Signaling in the Apoptotic Response of Macrophages to Yersinia Infection

  2003cited by this paper
• The Yersinia Virulence Factor YopM Forms a Novel Protein Complex with Two Cellular Kinases*

  2003cited by this paper
• Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases

  2003cited by this paper

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