Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder

BackgroundA recent report indicated that numbers of Sutterella spp. are elevated in gastrointestinal biopsies taken from children with autism spectrum disorder (ASD). We have recently reported changes in the numbers of some bacteria within the stool of ASD children, and now examine whether numbers of Sutterella spp. and some other mucosa-associated bacteria linked with gastrointestinal disease (Ruminococcus gnavus and Ruminococcus torques) are also altered in the stool of these children.FindingsWe show that numbers of Sutterella spp. are elevated in feces of ASD children relative to controls, and that numbers of R. torques are higher in the children with ASD with a reported functional gastrointestinal disorder than those without such a disorder.ConclusionsWe show further evidence of changes in the gut microbiota of children with ASD and confirm that the abundance of Sutterella spp. is altered in stool.

• Publication year

  2013

• Venue

  Molecular Autism

• Publication date

  2013-11-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/2040-2392-4-42PMID 24188502PMCID 3828002
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

  2013cited by this paper
• A review of the life history, invasion process, and potential management of Clavelina lepadiformis Müller, 1776: a recent invasion of the northwest Atlantic

  2012cited by this paper
• Application of Novel PCR-Based Methods for Detection, Quantitation, and Phylogenetic Characterization of Sutterella Species in Intestinal Biopsy Samples from Children with Autism and Gastrointestinal Disturbances

  2012influential reference
• Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

  2011cited by this paper
• Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

  2011influential reference
• A Comprehensive Evaluation of Colonic Mucosal Isolates of Sutterella wadsworthensis from Inflammatory Bowel Disease

  2011cited by this paper
• Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

  2011cited by this paper
• [Abnormal intestinal permeability in children with autism].

  2010cited by this paper
• Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives

  2010cited by this paper
• Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

  2010cited by this paper
• Pyrosequencing study of fecal microflora of autistic and control children.

  2010cited by this paper
• Sutterella parvirubra sp. nov. and Megamonas funiformis sp. nov., isolated from human faeces.

  2008cited by this paper
• qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

  2007cited by this paper
• Assembly of the human intestinal microbiota.

  2006cited by this paper
• Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children.

  2005cited by this paper
• Sutterella stercoricanis sp. nov., isolated from canine faeces.

  2004cited by this paper
• Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

  2002cited by this paper
• Prevalence of Campylobacter,Arcobacter, Helicobacter, andSutterella spp. in Human Fecal Samples as Estimated by a Reevaluation of Isolation Methods for Campylobacters

  2000cited by this paper
• Sources and antimicrobial susceptibilities of Campylobacter gracilis and Sutterella wadsworthensis.

  1997cited by this paper
• Abnormal intestinal permeability in children with autism

  1996cited by this paper
• Mucin degradation in human colon ecosystems. Isolation and properties of fecal strains that degrade ABH blood group antigens and oligosaccharides from mucin glycoproteins.

  1985cited by this paper
• Mucin degradation in human colon ecosystems. Evidence for the existence and role of bacterial subpopulations producing glycosidases as extracellular enzymes.

  1981cited by this paper

• Longitudinal multiomics analysis of endocrine therapy effects and gut microbiota in breast cancer recurrence

  2026cites this paper
• The impact of autism awareness of mothers of preschool children on the level of microbiota awareness.

  2026cites this paper
• Household Food Insecurity Alters Gut Microbiome Composition and Enriches Sutterella in Ethiopian Schoolchildren.

  2026cites this paper
• Bacterial genomic structural variations in children with autism serve as diagnostic biomarkers

  2026influential citation
• Gut–Brain Inflammatory Pathways in Attention-Deficit/Hyperactivity Disorder: The Role and Therapeutic Potential of Diet

  2025cites this paper
• Gut microbiota metabolites, secretory immunoglobulin A and Bayley-III cognitive scores in children from the CHILD Cohort Study

  2025cites this paper
• Gut Microbiota and Neurodevelopment in Preterm Infants: Mechanistic Insights and Prospects for Clinical Translation

  2025cites this paper
• Bidirectional crosstalk between the gut microbiota and cellular compartments of brain: Implications for neurodevelopmental and neuropsychiatric disorders

  2025cites this paper
• Perfil nutricional y alteraciones gastrointestinales en escolares con transtorno del espectro autista

  2025cites this paper
• Resilience of human gut microbiomes in autism spectrum disorder: measured using stiffness network analysis

  2025cites this paper
• Influential articles in autism and gut microbiota: bibliometric profile and research trends

  2025cites this paper
• Potential similarities in gut microbiota composition between autism spectrum disorder and neurotypical siblings: Insights from a comprehensive meta-analysis.

  2025cites this paper
• Gut microbiota signature in a cohort of Chinese patients with rosacea

  2025cites this paper
• Therapeutic efficacy of fecal microbiota transplantation in severe food intolerance: a case report

  2025cites this paper
• Double-edged sword effect of Sutterella in neurological disorders: implications for the gut-brain axis and neuroimmune interactions.

  2025cites this paper
• The Gut–Brain Axis in Autism: Inflammatory Mechanisms, Molecular Insights, and Emerging Microbiome-Based Therapies

  2025cites this paper
• Fecal Microbiota Transplantation (FMT): Historical Perspectives, Expanding Therapeutic Applications, and Future Prospects in Human Health

  2025cites this paper
• Investigating potential links between gut microbiome, clinical parameters, and mortality in long-living male patients receiving multi-drug therapy

  2025cites this paper
• Ruminococcus torques ameliorates the inflammation bowel disease and gut barrier dysfunction by modulating gut microbiota and bile acid metabolism

  2025cites this paper
• Study on the Effect of Radish Sprouts on Short-Chain Fatty Acids and Gut Microbial Diversity in Healthy Individuals

  2025cites this paper
• Gut microbiota, nutrients, and depression

  2025cites this paper
• Distinct in vitro utilization and degradation of porcine gastric mucin glycans by human intestinal bacteria

  2025cites this paper
• Clinical insights into the mechanisms of infectious microbes and microbiota in chronic neurologic and psychiatric diseases.

  2025cites this paper
• Dietary Entomophagy with Silkworm Pupae (Bombyx mori) and its Effect on Personalized Gut Microbiome and Host Health: A Comparative Analysis with Beef and Fish Diets

  2025cites this paper
• Microbial orchestration of neuroimmune crosstalk: from homeostasis to disease

  2025cites this paper
• Influence of Nonenzymatic Browning Reactions on the Digestibility and Gut Microbiota Fermentation of Starch and Protein

  2025cites this paper
• Microalgae-based bacteria for oral treatment of ASD through enhanced intestinal colonization and homeostasis

  2025cites this paper
• Uncovering novel endocannabinoidome-gut microbiome-brain axis-based therapeutic targets in a Fragile X Syndrome mouse model.

  2025cites this paper
• Gut Microbiotas, Plasma Metabolites, and Autism Spectrum Disorder: A Bidirectional Mendelian Randomization Analysis

  2025cites this paper
• Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial

  2025cites this paper
• The role of the microbiota-gut-brain axis in schizophrenia: an immunological perspective

  2025cites this paper
• Advancements in the Pathogenesis, Diagnosis, and Therapeutic Implications of Intestinal Bacteria

  2025cites this paper
• Targeting the gut microbiota-inflammation-brain axis as a potential therapeutic strategy for psychiatric disorders: A Mendelian randomization analysis.

  2025cites this paper
• Interventions targeting the gut microbiota and their possible effect on gastrointestinal and neurobehavioral symptoms in autism spectrum disorder

  2025cites this paper
• Comparative study of the gut microbiomes between Western and Indigenous cultures – implications for health and disease

  2025cites this paper
• An Altered Gut Microbiota–Brain Axis in Fragile X Syndrome May Explain Autistic Traits in Some Patients

  2025cites this paper
• The gut-microbiome in adult Attention-deficit/hyperactivity disorder - A Meta-analysis.

  2024cites this paper
• Intestinal flora and pregnancy complications: Current insights and future prospects

  2024cites this paper
• Regular Consumption of Black Tea Kombucha Modulates the Gut Microbiota in Individuals with and Without Obesity.

  2024cites this paper
• The role of fecal microbiota transplantation in selected neurodegenerative diseases and neurodevelopmental disorders

  2024cites this paper
• Comparative analysis of metagenomic classifiers for long-read sequencing datasets

  2024cites this paper
• Comparative analysis of gut microbiota in major depressive disorder and schizophrenia during hospitalisation - the case-control, post hoc study.

  2024cites this paper
• Fecal microbial marker panel for aiding diagnosis of autism spectrum disorders

  2024cites this paper
• Synergism of fermented feed and ginseng polysaccharide on growth performance, intestinal development, and immunity of Xuefeng black-bone chickens

  2024cites this paper
• Impact of Human Milk Oligosaccharides and Probiotics on Gut Microbiome and Mood in Autism: A Case Report

  2024cites this paper
• Modulation of Gut Microbiome and Autism Symptoms of ASD Children Supplemented with Biological Response Modifier: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study

  2024cites this paper
• Effects of rearing systems (cage versus floor) on the microbial composition and transcriptome of goose ileum

  2024cites this paper
• Association between pro-inflammatory diet and abdominal pain: Cross-sectional and case-control study from UK biobank and NHANES 2017-2020.

  2024cites this paper
• Microbiota and Autism: A Review on Oral and Gut Microbiome Analysis Through 16S rRNA Sequencing

  2024cites this paper
• Short-term dietary fiber interventions produce consistent gut microbiome responses across studies

  2024cites this paper
• Bimodal distribution of intestinal Candida in children with autism and its potential link with worse ASD symptoms

  2024cites this paper
• Alterations in the fecal microbiota of methamphetamine users with bad sleep quality during abstinence

  2024cites this paper
• Personalized identification of autism-related bacteria in the gut microbiome using explainable artificial intelligence

  2024cites this paper
• Causal links between gut microbiomes, cytokines and risk of different subtypes of epilepsy: a Mendelian randomization study

  2024cites this paper
• Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice

  2024cites this paper
• Interaction and Metabolic Pathways: Elucidating the Role of Gut Microbiota in Gestational Diabetes Mellitus Pathogenesis

  2024cites this paper
• Causal effects of gut microbiota on sepsis and sepsis-related death: insights from genome-wide Mendelian randomization, single-cell RNA, bulk RNA sequencing, and network pharmacology

  2024cites this paper
• Harnessing the Gut Microbiome: To What Extent Can Pre-/Probiotics Alleviate Immune Activation in Autism Spectrum Disorder?

  2024cites this paper
• The Complex Interplay Between Autism Spectrum Disorder and Gut Microbiota in Children: A Comprehensive Review.

  2024cites this paper
• The gut microbiome modulates the susceptibility to traumatic stress in a sex‐dependent manner

  2024cites this paper
• Discovering The Impact Of Dietary Interventions On Gut Microbiome And Human Health: The Clinical Trial Perspective

  2024cites this paper
• Crosstalk between gut microbiota and host immune system and its response to traumatic injury

  2024cites this paper
• Omic characterizing and targeting gut dysbiosis in children with autism spectrum disorder: symptom alleviation through combined probiotic and medium-carbohydrate diet intervention - a pilot study

  2024cites this paper
• Microbiota and social behavior alterations in a mouse model of down syndrome: Modulation by a synbiotic treatment.

  2024cites this paper
• Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome.

  2024cites this paper
• Bioinformatic Analysis of Sulfotransferases from an Unexplored Gut Microbe, Sutterella wadsworthensis 3_1_45B: Possible Roles towards Detoxification via Sulfonation by Members of the Human Gut Microbiome

  2024cites this paper
• Specific microbiome patterns and their association with breast cancer: the intestinal microbiota as a potential biomarker and therapeutic strategy

  2024cites this paper
• Dietary pattern in autism increases the need for probiotic supplementation: A comprehensive narrative and systematic review on oxidative stress hypothesis.

  2023cites this paper
• Genus-Level Analysis of Gut Microbiota in Children with Autism Spectrum Disorder: A Mini Review

  2023cites this paper
• Ketogenic diet: a potential adjunctive treatment for substance use disorders

  2023cites this paper
• The gut microbiota–brain axis in neurological disorder

  2023cites this paper
• Systematic Mendelian randomization study of the effect of gut microbiome and plasma metabolome on severe COVID-19

  2023cites this paper
• Different Diet Energy Levels Alter Body Condition, Glucolipid Metabolism, Fecal Microbiota and Metabolites in Adult Beagle Dogs

  2023cites this paper
• Maternal microbe-specific modulation of the offspring microbiome and development during pregnancy and lactation

  2023cites this paper
• Ruminococcus gnavus: friend or foe for human health

  2023cites this paper
• Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder

  2023cites this paper
• Fecal microbiota transplantation in a child with severe ASD comorbidities of gastrointestinal dysfunctions—a case report

  2023cites this paper
• The influence of antibiotic treatment on the behavior and gut microbiome of adult rats neonatally insulted with lipopolysaccharide

  2023cites this paper
• Maturation, Morphology, and Function: The Decisive Role of Intestinal Flora on Microglia: A Review.

  2023cites this paper
• Electroacupuncture Improves Depression-Like Behavior by Regulating the Abundance of Lactobacillus and Staphylococci in Mice.

  2023cites this paper
• The gut-microbiome in adult Attention-deficit/hyperactivity disorder - A Meta-analysis

  2023cites this paper
• The diagnostic and prognostic potential of gut bacteria in inflammatory bowel disease

  2023cites this paper
• Aerial transport of bacteria by dust plumes in the Eastern Mediterranean revealed by complementary rRNA/rRNA-gene sequencing

  2023cites this paper
• Cordyceps militaris polysaccharide alleviates diabetic symptoms by regulating gut microbiota against TLR4/NF-κB pathway.

  2023cites this paper
• Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis.

  2023cites this paper
• Partially hydrolyzed guar gum is associated with improvement in gut health, sleep, and motivation among healthy subjects

  2023cites this paper
• Short-term dietary fiber interventions produce consistent gut microbiome responses across studies

  2023cites this paper
• Chronic Strongyloides stercoralis infection increases presence of the Ruminococcus torques group in the gut and alters the microbial proteome

  2023cites this paper
• The Role of Short-Chain Fatty Acids and Altered Microbiota Composition in Autism Spectrum Disorder: A Comprehensive Literature Review

  2023cites this paper
• Age and severity-dependent gut microbiota alterations in Tunisian children with autism spectrum disorder

  2023cites this paper
• A longitudinal study of the gut microbiota during the first three years of life: Links with problem behavior and executive functions at preschool age.

  2023cites this paper
• Unraveling the connections between gut microbiota, stress, and quality of life for holistic care in newly diagnosed breast cancer patients

  2023cites this paper
• Machine Learning Algorithms Applied to Predict Autism Spectrum Disorder Based on Gut Microbiome Composition

  2023cites this paper
• From-Toilet-to-Freezer: A Review on Requirements for an Automatic Protocol to Collect and Store Human Fecal Samples for Research Purposes

  2023cites this paper
• Interpretable metric learning in comparative metagenomics: The adaptive Haar-like distance

  2023cites this paper
• Integrated Analysis of the Effects of Cecal Microbiota and Serum Metabolome on Market Weights of Chinese Native Chickens

  2023cites this paper
• The preventive effect of Glycyrrhiza polysaccharide on lipopolysaccharide-induced acute colitis in mice by modulating gut microbial communities.

  2023cites this paper
• Effect of White Jade Snail Secretions on the Antioxidant Capacity and Intestinal Microbial Diversity in Mice Model of Acute Gastric Ulcer.

  2023cites this paper
• Melatonin reduced colon inflammation but had no effect on energy metabolism in ageing Mongolian gerbils (Meriones unguiculatus).

  2023cites this paper
• Gut microbiota and Autism Spectrum Disorder: From pathogenesis to potential therapeutic perspectives

  2022cites this paper