Blueprint for schistosomiasis vaccine development.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Acta Tropica

• Publication date

  2002-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/S0001-706X(02)00048-7PMID 12020891
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vitro cellular and humoral responses to Schistosoma mansoni vaccine candidate antigens.

  2003cited by this paper
• Mathematical modelling of schistosomiasis japonica: comparison of control strategies in the People's Republic of China.

  2002cited by this paper
• Prevention and control of schistosomiasis and soil-transmitted helminthiasis.

  2002cited by this paper
• Praziquantel--quality, dosages and markers of resistance.

  2001cited by this paper
• Recombinant paramyosin (rec-Sj-97) tested for immunogenicity and vaccine efficacy against Schistosoma japonicum in mice and water buffaloes.

  2001cited by this paper
• Vaccine Strategies against Schistosomiasis: From Concepts to Clinical Trials

  2001cited by this paper
• Parasite vaccines--a reality?

  2001cited by this paper
• Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica.

  2000cited by this paper
• Susceptibility and resistance to Schistosoma mansoni reinfection: parallel cellular and isotypic immunologic assessment.

  2000cited by this paper
• The global status of schistosomiasis and its control.

  2000cited by this paper
• Identification of a candidate vaccine peptide on the 37 kDa Schistosoma mansoni GAPDH.

  2000cited by this paper
• Defining a schistosomiasis vaccination strategy - is it really Th1 versus Th2?

  2000cited by this paper
• Pathology and course of natural Schistosoma japonicum infection in pigs: results of a field study in Hubei province, China

  2000cited by this paper
• Human IgG1 and IgG3 recognition of Schistosoma mansoni 14kDa fatty acid-binding recombinant protein.

  2000cited by this paper
• Immunodiagnosis of schistosomiasis by determination of the circulating antigens CAA and CCA, in particular in individuals with recent or light infections.

  2000cited by this paper
• Human Immune Responses to Schistosoma mansoni Vaccine Candidate Antigens

  2000cited by this paper
• Praziquantel: is there real resistance and are there alternatives?

  2000cited by this paper
• Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers.

  1999cited by this paper
• Development of Antibody Isotype Responses to Schistosoma mansoni in an Immunologically Naive Immigrant Population: Influence of Infection Duration, Infection Intensity, and Host Age

  1999cited by this paper
• The search for a vaccine against schistosomiasis ‐ a difficult path hut an achievable goal

  1999cited by this paper
• Experimental murine schistosomiasis in the absence of B7 costimulatory molecules: reversal of elicited T cell cytokine profile and partial inhibition of egg granuloma formation.

  1999cited by this paper
• The search for a vaccine against schistosomiasis--a difficult path but an achievable goal.

  1999cited by this paper
• T and B cell reactivity to a 42-kDa protein is associated with human resistance to both schistosomiasis mansoni and haematobium.

  1998cited by this paper
• Helper T cell subsets: heterogeneity, functions and development.

  1998cited by this paper
• Dilemmas in drug development for tropical diseases. Experiences with praziquantel.

  1998cited by this paper
• Schistosomiasis vaccine:research to development.

  1998cited by this paper
• Schistosomiasis vaccine development: progress and prospects.

  1998cited by this paper
• Human schistosomiasis: potential long-term consequences of vaccination programmes.

  1997cited by this paper
• Immunity and morbidity in Schistosoma mansoni infection: quantitative aspects.

  1996cited by this paper
• Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni

  1996cited by this paper
• Lacto-N-fucopentaose III (Lewis x), a target of the antibody response in mice vaccinated with irradiated cercariae of Schistosoma mansoni

  1996cited by this paper
• Functional diversity of helper T lymphocytes

  1996cited by this paper
• Human schistosomiasis: potential consequences of vaccination.

  1995cited by this paper
• Synthetic peptide vaccines for schistosomiasis.

  1995cited by this paper
• Schistosomiasis vaccine development: approaches and prospects.

  1995cited by this paper
• Vaccination against schistosomiasis and fascioliasis with the new recombinant antigen Sm14: potential basis of a multi-valent anti-helminth vaccine?

  1995cited by this paper
• Resistance to Schistosoma mansoni in humans: influence of the IgE/IgG4 balance and IgG2 in immunity to reinfection after chemotherapy.

  1993cited by this paper
• Effector functions of activated macrophages against parasites.

  1993cited by this paper
• Protective immunity in baboons vaccinated with a recombinant antigen or radiation-attenuated cercariae of Schistosoma mansoni is antibody-dependent.

  1993cited by this paper
• The control of schistosomiasis. Second report of the WHO Expert Committee.

  1993cited by this paper
• Regulation of immunity to parasites by T cells and T cell-derived cytokines.

  1992cited by this paper
• Induction of protective immunity in mice using a 62-kDa recombinant fragment of a Schistosoma mansoni surface antigen.

  1992cited by this paper
• Schistosomiasis research funding: the TDR contribution

  1992cited by this paper
• Schistosomiasis: from effector and regulation mechanisms in rodents to vaccine strategies in humans.

  1992cited by this paper
• A protective monoclonal antibody specifically recognizes and alters the catalytic activity of schistosome triose-phosphate isomerase.

  1992cited by this paper
• Schistosomiasis research funding: the TDR (Special Programme for Research and Training in Tropical Diseases) contribution.

  1992cited by this paper
• Experimental models of immunization against schistosomes: lessons for vaccine development.

  1992cited by this paper
• Immunization against parasites: bridging the gap between attenuated and non-living vaccines.

  1991cited by this paper
• Human IgE, IgG4 and resistance to reinfection with Schistosomahaematobium

  1991cited by this paper
• The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase

  1989cited by this paper
• Induction of resistance to Schistosoma mansoni infection in mice by purified parasite paramyosin.

  1989cited by this paper
• Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen.

  1988cited by this paper
• The glutathione transferase activity and tissue distribution of a cloned Mr28K protective antigen of Schistosoma mansoni.

  1988cited by this paper
• Human resistance to Schistosoma mansoni is associated with IgG reactivity to a 37-kDa larval surface antigen.

  1988cited by this paper
• Immunity in human schistosomiasis mansoni: cross-reactive IgM and IgG2 anti-carbohydrate antibodies block the expression of immunity.

  1988cited by this paper
• Resistance to reinfection after treatment of urinary schistosomiasis.

  1987cited by this paper
• Cloning of a cDNA encoding a surface antigen of Schistosoma mansoni schistosomula recognized by sera of vaccinated mice.

  1987cited by this paper
• Immunity to schistosomes: progress toward vaccine.

  1987cited by this paper
• The control of schistosomiasis. Report of a WHO Expert Committee.

  1986cited by this paper
• Immunity after treatment of human schistosomiasis mansoni. II. Identification of resistant individuals, and analysis of their immune responses.

  1985cited by this paper
• Schistosoma and related genera: acquired resistance in mice.

  1983cited by this paper
• Multicentre trials of praziquantel in human schistosomiasis: design and techniques.

  1979cited by this paper
• Tierexperimentelle Untersuchungen zur Frage der Arsphenamin-Thrombopenie

  1964cited by this paper
• The control of schistosomiasis

  1952cited by this paper

• Functional characterization of differentially expressed proteins coming from unisexual and bisexual infected Schistosoma japonicum female worms.

  2023cites this paper
• Comparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections.

  2022cites this paper
• Proteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: 15k pellet and 120k pellet vesicles.

  2020cites this paper
• Immunization with adult Schistosoma mansoni tegument, treated with sub-curative praziquantel, partially protects mice against the infection.

  2019cites this paper
• Administration of anti‐CTLA‐4 monoclonal antibody augments protective immunity induced by Schistosoma japonicum glutathione‐S‐transferase

  2019cites this paper
• DNA vaccination using recombinant Schistosoma mansoni fatty acid binding protein (smFABP) gene.

  2018cites this paper
• Diagnosing Urogenital Schistosomiasis: Dealing with Diminishing Returns.

  2017cites this paper
• Humoral response and schistosomiasis susceptibility Authors

  2017cites this paper
• Sm-p80-Based Schistosomiasis Vaccine: Preparation for Human Clinical Trials.

  2017cites this paper
• Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Proteins

  2017cites this paper
• TREPAR 1597 No . of Pages 10 Diagnostic Tests for Urogenital Schistosomiasis

  2017cites this paper
• Anti-CD25 monoclonal antibody enhances the protective efficacy of Schistosoma japonicum GST vaccine via inhibition of CD4+CD25+Foxp3+ regulatory T cells

  2017cites this paper
• A field trial of recombinant Schistosoma japonicum paramyosin as a potential vaccine in naturally-infected water buffaloes

  2016cites this paper
• Specific humoral response of hosts with variable schistosomiasis susceptibility

  2016cites this paper
• Non-immune immunoglobulins shield Schistosoma japonicum from host immunorecognition

  2015cites this paper
• Transmission electron microscopic observations on ultrastructural alterations in Schistosoma mansoni adult worms recovered from C57BL/6 mice treated with radiation-attenuated vaccine and/or praziquantel in addition to passive immunization with normal and vaccinated rabbit sera against infection

  2015cites this paper
• Schistosomiasis in Egypt: A never-ending story?

  2015cites this paper
• Generation of a Novel Bacteriophage Library Displaying scFv Antibody Fragments from the Natural Buffalo Host to Identify Antigens from Adult Schistosoma japonicum for Diagnostic Development

  2015cites this paper
• Protective immunity against Schistosoma japonicum infection can be provided by IgG antibodies towards periodate-sensitive or periodate-resistant glycans

  2015cites this paper
• Schistosomiasis Vaccine: Research to Development

  2014cites this paper
• Parasitological, pathological and immunological effects of hesperidin treatment on murine schistosomiasis mansoni

  2014cites this paper
• Evaluation of the Schistosoma mansoni Y-box-binding protein (SMYB1) potential as a vaccine candidate against schistosomiasis

  2014cites this paper
• Serological Screening of the Schistosoma mansoni Adult Worm Proteome

  2014cites this paper
• Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon

  2014cites this paper
• Simultaneous priming with DNA encoding Sm-p80 and boosting with Sm-p80 protein confers protection against challenge infection with Schistosoma mansoni in mice

  2014cites this paper
• Complement plays a minimal role in Sm-p80-mediated protection against Schistosoma mansoni

  2014cites this paper
• Development and Use of qPCR Assays for Detection and Study of Neglected Tropical and Emerging Infectious Diseases

  2013cites this paper
• Edible vaccines against veterinary parasitic diseases--current status and future prospects.

  2013cites this paper
• Schistosoma Japonicum UDP-Glucose 4-Epimerase Protein Is Located on the Tegument and Induces Moderate Protection against Challenge Infection

  2012cites this paper
• Structural changes of Schistosoma mansoni adult worms recovered from C57BL/6 mice treated with radiation-attenuated vaccine and/or praziquantel against infection

  2012cites this paper
• Human cytokine responses during natural and experimental exposure to parasitic helminth infection

  2012cites this paper
• Sm14 Schistosoma mansoni Fatty Acid‐Binding Protein: Molecular Basis for an Antihelminth Vaccine

  2012cites this paper
• Seleção de um painel de antígenos biomarcadores de Schistosoma mansoni através de análises do proteoma sorológico

  2012cites this paper
• Screening trematodes for novel intervention targets

  2011cites this paper
• Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni

  2011cites this paper
• Schistosoma mansoni: molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages.

  2011cites this paper
• Cimetidine enhances the protective effect of GST DNA vaccine against Schistosoma japonicum.

  2011cites this paper
• Characterization of immunoglobulin G antibodies in baboons infected with schistosomiasis during vaccination and chemotherapy

  2011cites this paper
• Mapping the Binding between the Tetraspanin Molecule (Sjc23) of Schistosoma japonicum and Human Non-Immune IgG

  2011cites this paper
• Vaccine potential of hemocyanin from Oncomelania hupensis against Schistosoma japonicum.

  2011cites this paper
• Use of Schistosoma mansoni calreticulin, a highly immunogenic parasite antigen, in diagnosis of and vaccination against schistosomiasis

  2010influential citation
• Schistosomiasis vaccine discovery using immunomics

  2010cites this paper
• Development and immunogenicity of a recombinant pseudorabies virus expressing Sj26GST and SjFABP from Schistosoma japonicum.

  2010cites this paper
• Manipulation of the immune evasive properties of circulating cathodic antigen induces protective immunity against Schistosomiasis mansoni in C57BL/6 mice.

  2010cites this paper
• Cell cultures for schistosomes - Chances of success or wishful thinking?

  2010cites this paper
• Controlling schistosomiasis in Southeast Asia: a tale of two countries.

  2010cites this paper
• A comparative proteomic study of the undeveloped and developed Schistosoma mansoni egg and its contents: the miracidium, hatch fluid and secretions.

  2010cites this paper
• DNA vaccines: a rational design against parasitic diseases

  2010cites this paper
• Immunology and Immunopathology of Human Parasitic Infections

  2010cites this paper
• Immune events associated with protection in C57BL/6 mice immunized with anti-idiotypic antibodies mimicking protective antigens shared between gamma-irradiated cercariae vaccine and human resistance model of Schistosoma haematobium.

  2010cites this paper
• Antischistosomal Effects Of Solanum Incanum And Carica Papaya Crude Extracts On The Parasite Schistosoma Mansoni In Vivo And In Vitro

  2010cites this paper
• Schistosoma spp.: Isolation of microtubule associated proteins in the tegument and the definition of dynein light chains components.

  2009cites this paper
• Immunization with SmIg, a novel tegument protein from Schistosoma mansoni, fails to induce protection in mice but reduces liver pathology

  2009cites this paper
• Vaccines Against Schistosomiasis

  2009cites this paper
• Analysis of early hepatic stage schistosomula gene expression by subtractive expressed sequence tags library.

  2009cites this paper
• Immunoglobulin E (IgE) Responses to Paramyosin Predict Resistance to Reinfection with Schistosoma japonicum and Are Attenuated by IgG4

  2009cites this paper
• Molecular cloning and characterization of a paramyosin from Clonorchis sinensis.

  2009cites this paper
• Schistosoma japonicum: proteomics analysis of differentially expressed proteins from ultraviolet-attenuated cercariae compared to normal cercariae

  2009cites this paper
• Protective and antifecundity effects of Sm-p80-based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model.

  2009cites this paper
• Genomic analysis of the fresh water mollusc Biomphalaria glabrata to understand host : parasite interactions

  2009cites this paper
• And Are Attenuated by Igg4 Schistosoma Japonicum Reinfection with Paramyosin Predict Resistance to Immunoglobulin E (ige) Responses To

  2009cites this paper
• Expression of schistosomal cathepsin l1 in Escherichia coli and evaluation of its protective capacity in an animal challenge

  2009cites this paper
• Experimentally promising antischistosomal drugs: a review of some drug candidates not reaching the clinical use

  2009cites this paper
• Current Status of Vaccines for Schistosomiasis

  2008cites this paper
• Experimental vaccines in animal models for schistosomiasis

  2008cites this paper
• Heterologous expression of Schistosoma japanicum signal protein 14-3-3 in Pichia pastoris and the subsequent immune response in mice

  2008influential citation
• Targeted identification of Schistosoma mansoni egg glycans

  2008cites this paper
• Peptides containing T cell epitopes, derived from Sm14, but not from paramyosin, induce a Th1 type of immune response, reduction in liver pathology and partial protection against Schistosoma mansoni infection in mice.

  2008cites this paper
• Protective effect and granuloma down-modulation promoted by RP44 antigen a fructose 1,6 bisphosphate aldolase of Schistosoma mansoni.

  2008cites this paper
• Pilot-Scale Production and Characterization of Paramyosin, a Vaccine Candidate for Schistosomiasis Japonica

  2008cites this paper
• Oral immunization with Salmonella harboring a Sm14-based DNA vaccine does not protect mice against Schistosoma mansoni infection.

  2008cites this paper
• Scanning Electron Microscopical Studies on Schistosoma mansoni cercariae Exposed to Ultraviolet Irradiation

  2007cites this paper
• Construction and expression of DNA vaccine pIRES-Sj97-Sj14-Sj26 and its immunogenicity in mice

  2007cites this paper
• Integrating transcriptome, proteome and glycome analyses of Schistosoma biology.

  2007cites this paper
• Immunization of mice with cells from juvenile worms of Schistosoma japonicum provides immunoprotection against schistosomiasis

  2007cites this paper
• Mapping of the complement C9 binding domain in paramyosin of the blood fluke Schistosoma mansoni.

  2007cites this paper
• Amino Acid Transport in Schistosomes

  2007cites this paper
• Construction and expression of DNA vaccine pIRES-Sj97-Sj14-Sj26 and its immunogenicity in mice

  2007cites this paper
• The Schistosoma bovis Sb14-3-3zeta recombinant protein cross-protects against Schistosoma mansoni in BALB/c mice.

  2007cites this paper
• Gender biased differential alternative splicing patterns of the transcriptional cofactor CA150 gene in Schistosoma mansoni.

  2006cites this paper
• Immunization with Schistosoma mansoni 22.6 kDa antigen induces partial protection against experimental infection in a recombinant protein form but not as DNA vaccine.

  2006cites this paper
• Recombinant tegumental protein Shistosoma japonicum very lowdensity lipoprotein binding protein as a vaccine candidate against Schistosoma japonicum.

  2006cites this paper
• Protective immunity induced by phage displayed mitochondrial related peptides of Schistosoma japonicum.

  2006cites this paper
• Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections

  2006cites this paper
• Co-administration of plasmid expressing IL-12 with 14-kDa Schistosoma mansoni fatty acid-binding protein cDNA alters immune response profiles and fails to enhance protection induced by Sm14 DNA vaccine alone.

  2006cites this paper
• Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice.

  2006cites this paper
• Enzyme-linked immunosorbent assay with worm vomit and cercarial secretions of Schistosoma mansoni to detect infections in an endemic focus of Burkina Faso

  2006cites this paper
• New insights into the observed age-specific resistance to reinfection with Schistosoma japonicum.

  2006cites this paper
• Investigation of recombinant Schistosoma japonicum paramyosin fragments for immunogenicity and vaccine efficacy in mice

  2006cites this paper
• Serodiagnostics of schistosomiasis using keyhole limpet hemocyanin (KLH) as antigen

  2006cites this paper
• Apoptotic Plasmodium-infected hepatocytes provide antigens to liver dendritic cells.

  2005cites this paper
• DNA vaccines against tropical parasitic diseases

  2005cites this paper
• Characterization of the immune response to DNA vaccination strategies for schistosomiasis candidate antigen, Sm-p80 in the baboon.

  2005cites this paper
• Vaccine-linked chemotherapy: can schistosomiasis control benefit from an integrated approach?

  2005cites this paper
• Invertebrate muscles: muscle specific genes and proteins.

  2005cites this paper
• Phage displaying peptides mimic schistosoma antigenic epitopes selected by rat natural antibodies and protective immunity induced by their immunization in mice.

  2005cites this paper
• Are Ca2+ channels targets of praziquantel action?

  2005cites this paper
• Characterization of protective immunity induced against Schistosoma mansoni via DNA priming with the large subunit of calpain (Sm-p80) in the presence of genetic adjuvants.

  2005cites this paper
• Immunity induced by the radiation‐attenuated schistosome vaccine

  2005cites this paper
• Comparison of Schistosoma mansoni irradiated cercariae and Sm23 DNA vaccines

  2005cites this paper