Unveiling the role of post-translational modifications in bone metabolism: implications for osteoporosis

No abstract is available for this paper.

• Publication year

  2025

• Venue

  Medicine in Novel Technology and Devices

• Publication date

  2025-08-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1016/j.medntd.2025.100391
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• NEDD4 family E3 ligases in osteoporosis: mechanisms and emerging potential therapeutic targets

  2025cited by this paper
• Taxonomy, ecology, harvesting methods, ethnopharmacological use, trade and prospects for sustainable management of Prunus africana (Hook. f.) Kalkman (Rosaceae)

  2024cited by this paper
• Thermoelectric Materials and Devices for Advanced Biomedical Applications.

  2024cited by this paper
• Decoding Osteoporosis: Understanding the Disease, Exploring Current and New Therapies and Emerging Targets.

  2024cited by this paper
• The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex

  2024cited by this paper
• The role and mechanism of protein post‑translational modification in vascular calcification (Review)

  2024cited by this paper
• Sirt1: An Increasingly Interesting Molecule with a Potential Role in Bone Metabolism and Osteoporosis

  2024cited by this paper
• Emerging Roles of Natural Compounds in Osteoporosis: Regulation, Molecular Mechanisms and Bone Regeneration

  2024cited by this paper
• Hakai, a novel Runx2 interacting protein, augments osteoblast differentiation by rescuing Runx2 from Smurf2‐mediated proteasome degradation

  2024cited by this paper
• PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus

  2024cited by this paper
• Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

  2024cited by this paper
• Role of ubiquitination in the occurrence and development of osteoporosis (Review)

  2024cited by this paper
• Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development

  2024cited by this paper
• O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology

  2024cited by this paper
• Current perspectives on the multiple roles of osteoclasts: Mechanisms of osteoclast–osteoblast communication and potential clinical implications

  2024cited by this paper
• Engineering approaches to manipulate osteoclast behavior for bone regeneration

  2024cited by this paper
• A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver

  2024cited by this paper
• Altered Metabolism and Inflammation Driven by Post-translational Modifications in Intervertebral Disc Degeneration

  2024cited by this paper
• Protein Stability Regulation in Osteosarcoma: The Ubiquitin-like Modifications and Glycosylation as Mediators of Tumor Growth and as Targets for Therapy

  2024cited by this paper
• Exploring epigenetic strategies for the treatment of osteoporosis

  2024cited by this paper
• The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease

  2024cited by this paper
• Using Redox Proteomics to Gain New Insights into Neurodegenerative Disease and Protein Modification

  2024cited by this paper
• Mer tyrosine kinase regulates bone metabolism, and its deficiency partially ameliorates periodontitis- and ovariectomy-induced bone loss in mice

  2024cited by this paper
• Non-enzymatic posttranslational protein modifications in protein aggregation and neurodegenerative diseases

  2024cited by this paper
• Ferroptosis: mechanisms and therapeutic targets

  2024cited by this paper
• BMSC-derived exosomes promote osteoporosis alleviation via M2 macrophage polarization

  2024cited by this paper
• Targeting the mTOR-Autophagy Axis: Unveiling Therapeutic Potentials in Osteoporosis

  2024cited by this paper
• Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial

  2024cited by this paper
• Unlocking the Epigenetic Symphony: Histone Acetylation Orchestration in Bone Remodeling and Diseases

  2024cited by this paper
• Antiaging in a Bottle: Bioactive Competency of Plasma-Generated Nitric Oxide Water for Modulation of Aging-Related Signature in Human Dermal Cells.

  2024cited by this paper
• From Genomics to Metabolomics: Molecular Insights into Osteoporosis for Enhanced Diagnostic and Therapeutic Approaches

  2024cited by this paper
• A global view of the human post-translational modification landscape

  2023cited by this paper
• Immune homeostasis modulation by hydrogel-guided delivery systems: a tool for accelerated bone regeneration.

  2023cited by this paper
• Targeting strategies for bone diseases: signaling pathways and clinical studies

  2023cited by this paper
• Ubiquitin-specific proteases: Vital regulatory molecules in bone and bone-related diseases.

  2023cited by this paper
• The role of insulin-like growth factor-1 in bone remodeling: A review.

  2023cited by this paper
• Oxidative Stress and Natural Antioxidants in Osteoporosis: Novel Preventive and Therapeutic Approaches

  2023cited by this paper
• Intravital imaging of osteocyte integrin dynamic with locally injectable fluorescent nanoparticles.

  2023cited by this paper
• Progress of Wnt Signaling Pathway in Osteoporosis

  2023cited by this paper
• Ubiquitin‐specific peptidases: Players in bone metabolism

  2023cited by this paper
• Perspectives on molecular mechanisms of post-translational modification and their functional influence on certain diseases

  2023cited by this paper
• INSULIN RESISTANCE AND PATHOGENESIS OF POSTMENOPAUSAL OSTEOPOROSIS.

  2023cited by this paper
• Melatonin activates mitochondrial unfolded protein response to preserve osteogenic potential of senescent BMSCs via upregulating PDI-6.

  2023cited by this paper
• Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches

  2023cited by this paper
• Hormone-Related and Drug-Induced Osteoporosis: A Cellular and Molecular Overview

  2023cited by this paper
• Crosstalk Between Senescent Bone Cells and the Bone Tissue Microenvironment Influences Bone Fragility During Chronological Age and in Diabetes

  2022cited by this paper
• SUMOylation and NEDDylation in Primary and Metastatic Cancers to Bone

  2022cited by this paper
• The Interaction Between Intracellular Energy Metabolism and Signaling Pathways During Osteogenesis

  2022cited by this paper
• Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases

  2022cited by this paper
• Mechanical regulation of bone remodeling

  2022cited by this paper
• Bone Turnover Markers: Basic Biology to Clinical Applications

  2022cited by this paper
• SUMOylation in Skeletal Development, Homeostasis, and Disease

  2022cited by this paper
• Role of histone modification in the occurrence and development of osteoporosis

  2022cited by this paper
• Structural and Metabolic Changes in Bone

  2022cited by this paper
• Secondary Osteoporosis and Metabolic Bone Diseases

  2022cited by this paper
• Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib

  2021cited by this paper
• Natural Biopolymer-Based Biocompatible Conductors for Stretchable Bioelectronics.

  2021cited by this paper
• Combination Therapy of PTH and Antiresorptive Drugs on Osteoporosis: A Review of Treatment Alternatives

  2021cited by this paper
• A Novel cis Regulatory Element Regulates Human XIST in a CTCF-Dependent Manner

  2021cited by this paper
• Epigenetic modifications of histones during osteoblast differentiation.

  2021cited by this paper
• Nitrosative Stress and Human Disease: Therapeutic Potential of Denitrosylation

  2021cited by this paper
• Poor bone matrix quality: What can be done about it?

  2021cited by this paper
• Bisphosphonate-Based Conjugates and Derivatives as Potential Therapeutic Agents in Osteoporosis, Bone Cancer and Metastatic Bone Cancer

  2021cited by this paper
• Influence of the TGF-β Superfamily on Osteoclasts/Osteoblasts Balance in Physiological and Pathological Bone Conditions

  2020cited by this paper
• Lysine Methyltransferases Signaling: Histones are Just the Tip of the Iceberg.

  2020cited by this paper
• Downregulation of XIST ameliorates acute kidney injury by sponging miR‐142‐5p and targeting PDCD4

  2020cited by this paper
• Molecular mechanosensors in osteocytes

  2020cited by this paper
• Epigenetic and transcriptional regulation of osteoclast genesis in the pathogenesis of skeletal diseases: A systematic review.

  2020cited by this paper
• Epigenetic Regulation of Skeletal Tissue Integrity and Osteoporosis Development

  2020cited by this paper
• Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review)

  2020cited by this paper
• Molecular Signaling Pathways and Essential Metabolic Elements in Bone Remodeling: An Implication of Therapeutic Targets for Bone Diseases.

  2020cited by this paper
• Epigenetic Regulators Involved in Osteoclast Differentiation

  2020cited by this paper
• Pharmacological agents and natural compounds: available treatments for osteoporosis.

  2020cited by this paper
• Deciphering protein post-translational modifications using chemical biology tools

  2020cited by this paper
• Lactacystin: first-in-class proteasome inhibitor still excelling and an exemplar for future antibiotic research

  2019cited by this paper
• Ubiquitylomes Analysis of the Whole blood in Postmenopausal Osteoporosis Patients and healthy Postmenopausal Women

  2019cited by this paper
• Effects of valproic acid on bone mineral density and bone metabolism: A meta-analysis.

  2019cited by this paper
• Cross-Talk between Mitochondrial Dysfunction-Provoked Oxidative Stress and Aberrant Noncoding RNA Expression in the Pathogenesis and Pathophysiology of SLE

  2019cited by this paper
• Role of APD-Ribosylation in Bone Health and Disease

  2019cited by this paper
• Collagen and non-collagenous proteins molecular crosstalk in the pathophysiology of osteoporosis.

  2019cited by this paper
• Rational Design of Nanocarriers for Intracellular Protein Delivery

  2019cited by this paper
• Post-Translational Regulations of Transcriptional Activity of RUNX2

  2019cited by this paper
• Targeting therapeutics to bone by conjugation with bisphosphonates

  2018cited by this paper
• Epigenetics of Skeletal Diseases

  2018cited by this paper
• Bisphosphonate conjugation for bone specific drug targeting

  2018cited by this paper
• Long-Term Priming by Three Small Molecules Is a Promising Strategy for Enhancing Late Endothelial Progenitor Cell Bioactivities

  2018cited by this paper
• Collagen-the Ultrastructural Element of the Bone Matrix

  2018cited by this paper
• Features and regulation of non-enzymatic post-translational modifications.

  2018cited by this paper
• An HDAC Inhibitor, Entinostat/MS‐275, Partially Prevents Delayed Cranial Suture Closure in Heterozygous Runx2 Null Mice

  2017cited by this paper
• Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?

  2016cited by this paper
• Protein microarray applications: Autoantibody detection and posttranslational modification

  2016cited by this paper
• T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium Entry*

  2016cited by this paper
• Targeted delivery to bone and mineral deposits using bisphosphonate ligands.

  2016cited by this paper
• Regulation of Runx2 by Histone Deacetylases in Bone.

  2016cited by this paper
• PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption

  2016cited by this paper
• Epigenetic Regulation of Bone Remodeling and Its Impacts in Osteoporosis

  2016cited by this paper
• Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.

  2015cited by this paper
• Histone Deacetylases in Bone Development and Skeletal Disorders.

  2015cited by this paper
• Pharmacological diversity among drugs that inhibit bone resorption.

  2015cited by this paper
• Osteoblast‐Specific γ‐Glutamyl Carboxylase‐Deficient Mice Display Enhanced Bone Formation With Aberrant Mineralization

  2015cited by this paper

• No citing papers are available for this paper.