Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Internal Medicine

• Publication date

  2012-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1365-2796.2011.02502.xPMID 22443199
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Abstract P4-13-10: DoBRCA1andBRCA2mutation carriers have an earlier natural menopause than their non-carrier relatives: A study from the Kathleen Cuningham Foundation Consortium For Research Into Familial Breast Cancer (kConFab).:

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• Evaluation of Association Methods for Analysing Modifiers of Disease Risk in Carriers of High‐Risk Mutations

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• Genetic Variation in IGF2 and HTRA1 and Breast Cancer Risk among BRCA1 and BRCA2 Carriers

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• Common variants in ZNF365 are associated with both mammographic density and breast cancer risk

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• Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.

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• Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers.

  2011cited by this paper
• Confirmation of 5p12 As a Susceptibility Locus for Progesterone-Receptor–Positive, Lower Grade Breast Cancer

  2011cited by this paper
• Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes

  2011cited by this paper
• Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers.

  2011cited by this paper
• Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry.

  2011cited by this paper
• Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers.

  2011cited by this paper
• The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers

  2011cited by this paper
• A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact

  2011cited by this paper
• Modification of BRCA 1-Associated Breast and Ovarian Cancer Risk by BRCA 1-Interacting Genes

  2011cited by this paper
• Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

  2011cited by this paper
• Genetic Variation in IGF 2 and HTRA 1 and Breast Cancer Risk among BRCA 1 and BRCA 2 Carriers

  2011cited by this paper
• Prospective study of breast cancer risk in mutation-negative women from BRCA1 or BRCA2 mutation-positive families in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab).

  2011cited by this paper
• Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2

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  2011cited by this paper
• Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes.

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• Ancestry-Shift Refinement Mapping of the C6orf97-ESR1 Breast Cancer Susceptibility Locus

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• A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

  2010cited by this paper
• Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

  2010cited by this paper
• Genome-wide association study identifies five new breast cancer susceptibility loci

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• A Genome-Wide Association Study Identifies A New Ovarian Cancer Susceptibility Locus On 9 p 22 . 2

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• Common variants at 19p13 are associated with susceptibility to ovarian cancer

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• Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

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• Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

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• Reproductive and Hormonal Factors, and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Results from the International BRCA1/2 Carrier Cohort Study

  2009cited by this paper
• The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

  2009cited by this paper
• Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

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• A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

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• Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)

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  2009cited by this paper
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• Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

  2008cited by this paper
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  2008cited by this paper
• Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

  2008cited by this paper
• Variation of breast cancer risk among BRCA1/2 carriers.

  2008cited by this paper
• The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

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• Prediction of individual genetic risk of complex disease.

  2008cited by this paper
• Genome-wide association study identifies novel breast cancer susceptibility loci

  2008cited by this paper
• The average cumulative risks of breast and ovarian cancer for carriers of mutations in BRCA1 and BRCA2 attending genetic counseling units in Spain.

  2008cited by this paper
• Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

  2008cited by this paper
• Polygenes, risk prediction, and targeted prevention of breast cancer.

  2008cited by this paper
• A common coding variant in CASP8 is associated with breast cancer risk

  2007cited by this paper
• An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

  2007cited by this paper
• Age at Menarche and Menopause and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study

  2007cited by this paper
• Genome-wide association study identifies novel breast cancer susceptibility loci

  2007cited by this paper
• RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.

  2007cited by this paper
• Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer

  2007cited by this paper
• Assessing Environmental Modifiers of Disease Risk Associated with Rare Mutations

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• Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group.

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• Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.

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  2006cited by this paper
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• Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.

  2005cited by this paper
• Oral Contraceptive Use and Risk of Early-Onset Breast Cancer in Carriers and Noncarriers of BRCA1 and BRCA2 Mutations

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• Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers

  2005cited by this paper
• Emerging functions of BRCA2 in DNA recombination.

  2004cited by this paper
• The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers

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• A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers

  2004cited by this paper
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  2004cited by this paper
• Association of a common variant of the CASP8 gene with reduced risk of breast cancer.

  2004cited by this paper
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  2003cited by this paper
• EMGM Abstracts

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  2003cited by this paper
• Heritability of mammographic density, a risk factor for breast cancer.

  2002cited by this paper
• Variation in BRCA1 cancer risks by mutation position.

  2002cited by this paper
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  2002cited by this paper
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• DNA double strand break repair in mammalian cells.

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