Elucidation of the zinc binding site in KCNQ channels

KCNQ1‐5 (Kv7.1–7.5) are members of a family of voltage‐gated potassium channels with prominent function in the nervous and cardiovascular systems and in epithelia. KCNQ channels are activated by intracellular free zinc, but the molecular mechanism of this effect is poorly understood and zinc binding sites within KCNQ channels are elusive.

• Publication year

  2025

• Venue

  British Journal of Pharmacology

• Publication date

  2025-08-20

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/bph.70177PMID 40831387
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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