Validating objective, brain‐based indices of consciousness in behaviorally unresponsive patients represents a challenge due to the impossibility of obtaining independent evidence through subjective reports. Here we address this problem by first validating a promising metric of consciousness—the Perturbational Complexity Index (PCI)—in a benchmark population who could confirm the presence or absence of consciousness through subjective reports, and then applying the same index to patients with disorders of consciousness (DOCs).
Stratification of unresponsive patients by an independently validated index of brain complexity
S. Casarotto,A. Comanducci,M. Rosanova,S. Sarasso,M. Fecchio,M. Napolitani,A. Pigorini,Adenauer G Casali,P. Trimarchi,M. Boly,O. Gosseries,O. Bodart,F. Curto,C. Landi,M. Mariotti,G. Devalle,Steven Laureys,G. Tononi,M. Massimini
Published 2016 in Annals of Neurology
ABSTRACT
PUBLICATION RECORD
- Publication year
2016
- Venue
Annals of Neurology
- Publication date
2016-11-01
- Fields of study
Medicine, Psychology
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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