CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

High‐fidelity (HF) long‐read sequencing enables accurate profiling of microorganisms and pathogens at single‐molecule resolution. However, current Oxford Nanopore Technologies (ONT)—a revolutionary platform offering real‐time, portable sequencing at relatively low instrumental cost—suffer from severe read‐length bias, limited accuracy (often

• Publication year

  2025

• Venue

  Advancement of science

• Publication date

  2025-09-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/advs.202505978PMID 40936099PMCID 12667459
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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