Novel 45-Kilodalton Leptospiral Protein That Is Processed to a 31-Kilodalton Growth-Phase-Regulated Peripheral Membrane Protein

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Infection and Immunity

• Publication date

  2002-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.70.1.323-334.2002PMID 11748198PMCID PMC127625
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• First evidence for gene replacement in Leptospira spp. Inactivation of L. biflexa flaB results in non‐motile mutants deficient in endoflagella

  2001cited by this paper
• Phase Separation of Integral Membrane Proteins in Triton X-114 Solution

  2001influential reference
• Virulence Functions of Autotransporter Proteins

  2001cited by this paper
• Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis

  2001cited by this paper
• Penicillin-Binding Proteins inLeptospira interrogans

  2001cited by this paper
• Identification of a 36-kDa fibronectin-binding protein expressed by a virulent variant of Leptospira interrogans serovar icterohaemorrhagiae.

  2000cited by this paper
• The Leptospiral Major Outer Membrane Protein LipL32 Is a Lipoprotein Expressed during Mammalian Infection

  2000influential reference
• Spirochaetal lipoproteins and pathogenesis.

  2000cited by this paper
• Inverse Relation between Disease Severity and Expression of the Streptococcal Cysteine Protease, SpeB, among Clonal M1T1 Isolates Recovered from Invasive Group A Streptococcal Infection Cases

  2000cited by this paper
• Lipopolysaccharide biosynthesis in Leptospira.

  2000influential reference
• A PhoP-Regulated Outer Membrane Protease of Salmonella enterica Serovar Typhimurium Promotes Resistance to Alpha-Helical Antimicrobial Peptides

  2000cited by this paper
• Evidence of cross-protection within Leptospira interrogans in an experimental model.

  2000cited by this paper
• rpoB Gene Analysis as a Novel Strategy for Identification of Spirochetes from the Genera Borrelia,Treponema, and Leptospira

  2000cited by this paper
• Leptospiral Outer Membrane Proteins OmpL1 and LipL41 Exhibit Synergistic Immunoprotection

  1999cited by this paper
• Further determination of DNA relatedness between serogroups and serovars in the family Leptospiraceae with a proposal for Leptospira alexanderi sp. nov. and four new Leptospira genomospecies.

  1999cited by this paper
• Expression and Immunologic Characterization of Recombinant Heat Shock Protein 58 of Leptospira Species: A Major Target Antigen of the Humoral Immune Response

  1999cited by this paper
• Expression and Distribution of Leptospiral Outer Membrane Components during Renal Infection of Hamsters

  1999influential reference
• Membrane Topology and Cellular Location of the Treponema pallidum Glycerophosphodiester Phosphodiesterase (GlpQ) Ortholog

  1999cited by this paper
• Characterization of Leptospiral Outer Membrane Lipoprotein LipL36: Downregulation Associated with Late-Log-Phase Growth and Mammalian Infection

  1998influential reference
• Molecular analysis of the dnaK locus of Leptospira interrogans serovar Copenhageni.

  1998cited by this paper
• Molecular characterization and cellular localization of TpLRR, a processed leucine-rich repeat protein of Treponema pallidum, the syphilis spirochete

  1997cited by this paper
• Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity.

  1997cited by this paper
• Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family

  1996cited by this paper
• Molecular cloning and sequence analysis of the gene encoding LipL41, a surface-exposed lipoprotein of pathogenic Leptospira species

  1996influential reference
• Borrelia burgdorferi genes selectively expressed in the infected host.

  1995cited by this paper
• The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin

  1995cited by this paper
• Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo

  1995cited by this paper
• Molecular analysis of the hsp (groE) operon of Leptospira interrogans serovar copenhageni

  1993influential reference
• Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira spp

  1993cited by this paper
• Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA

  1993cited by this paper
• One-hour downward alkaline capillary transfer for blotting of DNA and RNA.

  1992cited by this paper
• Changes in the surface of Leptospira interrogans serovar grippotyphosa during in vitro cultivation

  1991cited by this paper
• Molecular and immunological analysis of a polymorphic periplasmic protein of Borrelia burgdorferi

  1991cited by this paper
• Protein and antigen profiles of prevalent serovars of Leptospira interrogans

  1991cited by this paper
• Characterization of outer membrane and secreted proteins of Leptospira interrogans serovar pomona.

  1991cited by this paper
• Lipoproteins in bacteria

  1990cited by this paper
• Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins

  1990cited by this paper
• Purification and characterization of a protein antigen from Leptospira interrogans serovar hardjo, common to a wide range of bacteria.

  1990cited by this paper
• Effect of vaccination with a pentavalent leptospiral vaccine containing Leptospira interrogans serovar hardjo type hardjo-bovis on type hardjo-bovis infection of cattle.

  1989cited by this paper
• Molecular characterization of the pathogen-specific, 34-kilodalton membrane immunogen of Treponema pallidum

  1989cited by this paper
• Experimental immunisation of hamsters with lipopolysaccharide antigens of Leptospira interrogans.

  1989cited by this paper
• Major integral membrane protein immunogens of Treponema pallidum are proteolipids

  1989cited by this paper
• A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis.

  1986cited by this paper
• Identification and characterization of the protein antigens of Leptospira interrogans serovar hardjo

  1985cited by this paper
• Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes.

  1985cited by this paper
• Cloning of a gene required for tryptophan biosynthesis from Leptospira biflexa serovar patoc into Escherichia coli.

  1984cited by this paper
• Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum

  1982cited by this paper
• Phase separation of integral membrane proteins in Triton X-114 solution.

  1981cited by this paper
• The route of entry of leptospires into the kidney tubule.

  1976cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Differentiation of Pathogenic and Saprophytic Leptospires I. Growth at Low Temperatures

  1967cited by this paper
• RETICULOENDOTHELIAL PHAGOCYTOSIS OF VIRULENT LEPTOSPIRES.

  1964cited by this paper
• The growth of Leptospira australis B in the kidneys of mice in the incipient experimental carrier state

  1962cited by this paper
• New Simple Silver Stain for Demonstration of Bacteria, Spirochetes, and Fungi in Sections from Paraffin-Embedded Tissue Blocks.

  1944cited by this paper

• Exoproteome Profiling Reveals Increased Secretion of Adhesins and Proteases by Leptospira interrogans to Facilitate Host Colonization and Immune Modulation

  2025cites this paper
• Leptospiral LipL45 lipoprotein undergoes processing and shares structural similarities with bacterial sigma regulators.

  2024cites this paper
• The leptospiral OmpA-like protein (Loa22) is a surface-exposed antigen that elicits bactericidal antibody against heterologous Leptospira

  2023cites this paper
• Some like it hot, some like it cold; proteome comparison of Leptospira borgpetersenii serovar Hardjo strains propagated at different temperatures.

  2022cites this paper
• Riboflavin salvage by Borrelia burgdorferi supports carbon metabolism and is essential for survival in the tick vector

  2022cites this paper
• hTLR2 interacting peptides of pathogenic leptospiral outer membrane proteins.

  2021cites this paper
• Distinct transcriptional profiles of Leptospira borgpetersenii serovar Hardjo strains JB197 and HB203 cultured at different temperatures

  2021influential citation
• The Leptospiral General Secretory Protein D (GspD), a secretin, elicits complement-independent bactericidal antibody against diverse Leptospira species and serovars

  2021cites this paper
• The interplay between host haemostatic systems and Leptospira spp. infections

  2020cites this paper
• Heparin-Binding Protein Release Is Strongly Induced by Leptospira Species and Is a Candidate for an Early Diagnostic Marker of Human Leptospirosis

  2018cites this paper
• In Silico B Cell and T Cell Epitopes Evaluation of lipL32 and OmpL1 Proteins for Designing a Recombinant Multi-Epitope Vaccine Against Leptospirosis

  2018cites this paper
• Leptospira interrogans outer membrane protein LipL21 is a potent inhibitor of neutrophil myeloperoxidase

  2018cites this paper
• Human leptospirosis vaccines in China

  2018cites this paper
• DNA vaccines against leptospirosis: A literature review.

  2017cites this paper
• Chapter 6 References

  2017cites this paper
• Pathogenic Leptospires Modulate Protein Expression and Post-translational Modifications in Response to Mammalian Host Signals

  2017influential citation
• 10 Insights into Leptospirosis , a Neglected Disease

  2017cites this paper
• Multiple specificities of immunoglobulin M in equine fetuses infected with Leptospira interrogans indicate a competent immune response.

  2016cites this paper
• Chimeric epitope vaccine against Leptospira interrogans infection and induced specific immunity in guinea pigs

  2016cites this paper
• Preliminary evaluation of a dual antigen ELISA to distinguish vaccinated from Leptospira infected horses

  2016cites this paper
• Evaluation of Cell Binding Activities of Leptospira ECM Adhesins

  2015cites this paper
• Pathogenic, diagnostic and vaccine potential of leptospiral outer membrane proteins (OMPs)

  2015cites this paper
• Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45

  2015cites this paper
• Evaluation of Recombinant Proteins Based Indirect ELISA and Microscopic Agglutination Test for Seroprevalence Study of Feline Leptospirosis

  2015cites this paper
• Comparative subproteome analysis of three representative Leptospira interrogans vaccine strains reveals cross-reactive antigens and novel virulence determinants.

  2015cites this paper
• The leptospiral outer membrane.

  2015influential citation
• Cloning, Phylogenetic Analysis and Expression of Recombinant LipL41, Loa22 and LipL21 Proteins from Leptospira interrogans

  2014cites this paper
• The Characteristics of Ubiquitous and Unique Leptospira Strains from the Collection of Russian Centre for Leptospirosis

  2014cites this paper
• SDS- PAGE STUDY ON LEPTOSPIRA AUTUMNALIS PROTEIN DAMAGE DUE TO PHYLLANTHUS AMARUS AND ECLIPTA ALBA

  2013cites this paper
• Avaliação da atividade imunogênica de três proteínas de Leptospira interrogans expressas em Escherichia coli.

  2013cites this paper
• LipL32 Is a Subsurface Lipoprotein of Leptospira interrogans: Presentation of New Data and Reevaluation of Previous Studies

  2013cites this paper
• Low-level laser therapy: Clearly a New Paradigm in the Management of Cancer Therapy-Induced Mucositis

  2013cites this paper
• Replacement of hamsters with physiochemical analytical methods fo Leptospira vaccine batch potency testing

  2013influential citation
• Analysis of Multiple Leptospira interrogans Serovar Canicola Vaccine Proteomes and Identification of LipL32 as a Biomarker for Potency

  2012cites this paper
• Leptospirosis-persistence of a dilemma: an overview with particular emphasis on trends and recent advances in vaccines and vaccination strategies.

  2012cites this paper
• Insights into Leptospirosis, a Neglected Disease

  2012cites this paper
• Cross-protection among unrelated leptospira pathogens serovars: an unfinished story.

  2012cites this paper
• Characterisation of the membrane and protein interactions of the Hepatitis C Virus NS2

  2011cites this paper
• Caracterização das proteínas de superfície de membrana externa da sorovariedade Hardjo isolada de bovinos em Minas Gerais

  2011cites this paper
• Development of Transcriptional Fusions to Assess Leptospira interrogans Promoter Activity

  2011cites this paper
• Leptospira: a spirochaete with a hybrid outer membrane

  2010cites this paper
• Comparative Transcriptional and Translational Analysis of Leptospiral Outer Membrane Protein Expression in Response to Temperature

  2009cites this paper
• A Comprehensive Approach to Identification of Surface-Exposed, Outer Membrane-Spanning Proteins of Leptospira interrogans

  2009influential citation
• Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity.

  2009cites this paper
• Immune strategies using single-component LipL32 and multi-component recombinant LipL32-41-OmpL1 vaccines against leptospira.

  2009cites this paper
• Proteome Analysis of Leptospira interrogans Virulent Strain

  2009cites this paper
• Chapter 64 – Leptospirosis

  2009cites this paper
• Entwicklung einer quantitativen PCR zum Nachweis von DNA pathogener Leptospiren in Glaskörper- und Kammerwasserproben von Pferden

  2008cites this paper
• Leptospirosis vaccines

  2007cites this paper
• Genetic diversity among major endemic strains of Leptospira interrogans in China

  2007cites this paper
• Leptospirosis: pathogenesis, immunity, and diagnosis

  2007cites this paper
• Recombinant Mycobacterium bovis BCG expressing the LipL32 antigen of Leptospira interrogans protects hamsters from challenge.

  2007cites this paper
• Effects of Temperature on Gene Expression Patterns in Leptospira interrogans Serovar Lai as Assessed by Whole-Genome Microarrays

  2006cites this paper
• Immunoreactive outer membrane proteins of Leptospira interrogans serovar Canicola strain Hond Utrecht IV.

  2006cites this paper
• LipL46 is a novel surface-exposed lipoprotein expressed during leptospiral dissemination in the mammalian host.

  2006cites this paper
• Characterization of the Outer Membrane Proteome of Leptospira interrogans Expressed during Acute Lethal Infection

  2006cites this paper
• Leptospirosis vaccines: past, present, and future.

  2005cites this paper
• Surfaceome of Leptospira spp

  2005cites this paper
• Expression and comparative analysis of genes encoding outer membrane proteins LipL21, LipL32 and OmpL1 in epidemic leptospires.

  2005cites this paper
• LruA and LruB, Novel Lipoproteins of Pathogenic Leptospira interrogans Associated with Equine Recurrent Uveitis

  2005cites this paper
• Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni

  2005cites this paper
• Osmolarity, a Key Environmental Signal Controlling Expression of Leptospiral Proteins LigA and LigB and the Extracellular Release of LigA

  2005cites this paper
• Omp52 is a growth-phase-regulated outer membrane protein of Leptospira santarosai serovar Shermani.

  2005cites this paper
• Molecular Evolution and Mosaicism of Leptospiral Outer Membrane Proteins Involves Horizontal DNA Transfer

  2004cites this paper
• Leptospiral immunoglobulin-like proteins elicit protective immunity.

  2004cites this paper
• Genome features of Leptospira interrogans serovar Copenhageni.

  2004influential citation
• Outer membrane proteins of pathogenic spirochetes.

  2004cites this paper
• Cell aggregation: a mechanism of pathogenic Leptospira to survive in fresh water.

  2004cites this paper
• Host-Inducible Immunogenic Sphingomyelinase-Like Protein, Lk73.5, of Leptospira interrogans

  2004cites this paper
• LipL21 Is a Novel Surface-Exposed Lipoprotein of Pathogenic Leptospira Species

  2003cites this paper
• Pathogenic Leptospira species express surface‐exposed proteins belonging to the bacterial immunoglobulin superfamily

  2003influential citation
• Characterization of host-bacteria interactions contributing to group B streptococcus colonization

  2002cites this paper