A Comprehensive Review of Solubility Enhancement Techniques for Poorly Soluble Drugs

No abstract is available for this paper.

• Publication year

  2025

• Venue

  Journal of Solution Chemistry

• Publication date

  2025-10-06

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1007/s10953-025-01502-y
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Recent advancements in nanoparticles for cancer treatment

  2025cited by this paper
• Current advancements in nanoparticles for vaccines and drug delivery for the treatment of tuberculosis.

  2025cited by this paper
• Nanotechnology-based drug delivery system for the diagnosis and treatment of ovarian cancer

  2025cited by this paper
• Lipid Nanoparticles: Formulation, Production Methods and Characterization Protocols

  2025cited by this paper
• Cyclodextrin-based nanosponges for the dispersive-solid phase extraction of pesticides from environmental waters

  2024cited by this paper
• A review on solubility enhancement technique

  2024cited by this paper
• Recent advances in medical applications of chitosan-based biomaterials

  2024cited by this paper
• Contemporary Review on Solubility Enhancement Techniques

  2023influential reference
• Co-Crystallization Approach to Enhance the Stability of Moisture-Sensitive Drugs

  2023cited by this paper
• Review on Solubility Enhancement Techniques for Poorly Soluble Drugs

  2023cited by this paper
• Solubility Enhancement Technique: A Review

  2023cited by this paper
• Novel Approaches to Enhance Solubility Medicine

  2023cited by this paper
• Recent developments in nanoparticles for the treatment of diabetes

  2023cited by this paper
• Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs

  2023cited by this paper
• Novel Applications of Hot Melt Extrusion Technology

  2023cited by this paper
• Solubility enhancement techniques: A comprehensive review

  2023cited by this paper
• Development and in-vitro, in-vivo evaluation of Pioglitazone-loaded polymeric nanoparticles using central composite design surface response methodology

  2023cited by this paper
• Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques

  2022cited by this paper
• Techniques For Increasing Solubility: A Review Of Conventional And New Strategies

  2022cited by this paper
• Solubility Enhancement Techniques: An Overview

  2022cited by this paper
• Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

  2022cited by this paper
• Self-emulsifying drug delivery systems: a novel approach to deliver drugs

  2022cited by this paper
• Preparation and in-vitro, in-vivo characterisation of pioglitazone loaded chitosan/PEG blended PLGA biocompatible nanoparticles

  2022cited by this paper
• A review on solubility enhancement methods for poorly water-soluble drugs

  2021cited by this paper
• Solubility enhancement, solvent effect and thermodynamic analysis of pazopanib in co-solvent mixtures

  2021cited by this paper
• Improved Bioavailability of Poorly Water-Soluble Drug by Targeting Increased Absorption through Solubility Enhancement and Precipitation Inhibition

  2021cited by this paper
• A novel integrated structure for hydrogen purification using the cryogenic method

  2021cited by this paper
• Cocrystallization of Trimethoprim and Solubility Enhancement via Salt Formation

  2021cited by this paper
• Application of Thermodynamic Phase Diagrams and Gibbs Free Energy of Mixing for Screening of Polymers for Their Use in Amorphous Solid Dispersion Formulation of a Non-Glass-Forming Drug.

  2021cited by this paper
• Vicissitudes of liquid crystals for solubility enhancement of poorly soluble drugs

  2021cited by this paper
• Application of supercritical fluid technology for solid dispersion to enhance solubility and bioavailability of poorly water-soluble drugs.

  2021cited by this paper
• Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach

  2021cited by this paper
• Bioavailability Enhancement Techniques for Poorly Soluble Drugs: A Review

  2020cited by this paper
• Solubility Enhancement of Poorly soluble Drugs by using Novel Techniques : A Comprehensive Review

  2020cited by this paper
• Solubilisation of dexamethasone: experimental data, co-solvency and Polarised Continuum Modelling

  2020cited by this paper
• LIQUISOLID-PELLETS TECHNIQUE: A RECENT TECHNIQUE FOR ENHANCING SOLUBILITY AND BIOAVAILABILITY OF DRUGS

  2020cited by this paper
• Nanonization techniques to overcome poor water-solubility with drugs

  2020cited by this paper
• Pharmaceutical Co-Crystallization: Regulatory Aspects, Design, Characterization, and Applications

  2020cited by this paper
• IMPORTANCE OF SOLUBILITY AND SOLUBILITY ENHANCEMENT TECHNIQUES

  2019cited by this paper
• Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs

  2019cited by this paper
• Mechanisms of increased bioavailability through amorphous solid dispersions: a review

  2019cited by this paper
• Solubility Enhancement by Various Techniques based on Pharmaceutical and Medicinal Chemistry Approach: An Overview

  2019cited by this paper
• Solubility enhancement (Solid Dispersions) novel boon to increase bioavailability

  2019cited by this paper
• Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility

  2019cited by this paper
• Chemical Modification: A unique solutions to Solubility problem

  2019cited by this paper
• Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds

  2018cited by this paper
• Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs

  2018cited by this paper
• Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation–Processing Aspects and Challenges

  2018cited by this paper
• Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling

  2018cited by this paper
• Tuning the Particle Sizes in Spherical Agglomeration

  2018cited by this paper
• Spherical Crystallization in Solubility Enhancement

  2018cited by this paper
• Spherical crystallization: A technique use to reform solubility and flow property of active pharmaceutical ingredients

  2017cited by this paper
• Polymeric mixed micelles as nanomedicines: Achievements and perspectives.

  2017cited by this paper
• REVIEW ARTICLE: SOLUBILITY ENHANCEMENT BY SOLID DISPERSION

  2017cited by this paper
• Solubility Enhancement Techniques for Poorly Water-Soluble Drugs

  2017cited by this paper
• NEAR INFRA RED SPECTROSCOPIC ANALYSIS OF MACROTYLOMA UNIFLORUM (LAM.) VERDC., PHASEOLUS LUNATUS LINN. A ND PHASEOLUS VULGARIS LINN.

  2016cited by this paper
• Improved delivery of poorly soluble compounds using nanoparticle technology: a review

  2016cited by this paper
• Spherical Agglomeration of Platy Crystals: Curious Case of Etodolac

  2016cited by this paper
• A REVIEW - SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUGS

  2016cited by this paper
• DRUG SOLUBILITY : IMPORTANCE AND ENHANCEMENT TECHNIQUES

  2016cited by this paper
• Various techniques for solubility enhancement: An overview

  2016cited by this paper
• Techniques to Enhance Solubility of Hydrophobic Drugs: An Overview

  2016cited by this paper
• Nanosponges: A Novel Drug Delivery System

  2016cited by this paper
• Survey of supercritical fluid techniques for producing drug delivery systems for a potential use in cancer therapy

  2016cited by this paper
• A new self-emulsifying formulation of mefenamic acid with enhanced drug dissolution

  2015cited by this paper
• Liquisolid Compact Technique for Improvement of the Dissolution Rate of Flurbiprofen: Formulation and Evaluation

  2015cited by this paper
• Solubility and dissolution enhancement strategies: current understanding and recent trends*

  2015cited by this paper
• Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs

  2015cited by this paper
• Strategies for formulating and delivering poorly water-soluble drugs

  2015cited by this paper
• ADVANCED DELIVERY OF POORLY WATER SOLUBLE DRUGS BY LIPID BASED FORMULATION AS SMEDDS

  2015cited by this paper
• Poorly Water Soluble Drugs : Change in Solubility for Improved Dissolution Characteristics a Review

  2014cited by this paper
• An overview on in situ micronization technique - An emerging novel concept in advanced drug delivery.

  2014cited by this paper
• Drug loading and release from electrospun biodegradable nanofibers.

  2014cited by this paper
• Solubility Enhancement of Poorly Soluble Drugs by Using Novel Techniques: A Review

  2014cited by this paper
• Polymeric Micelles: Nanocarriers for Cancer-Targeted Drug Delivery

  2014cited by this paper
• The application of nanosponges to cancer drug delivery

  2014cited by this paper
• Nanosponges: a potential nanocarrier for novel drug delivery-a review

  2014cited by this paper
• SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUGS: A REVIEW

  2014cited by this paper
• Review of patents and application of spray drying in pharmaceutical, food and flavor industry.

  2014cited by this paper
• VARIOUS TECHNIQUES ENHANCING BIOAVAILABILTY OF POORLY WATER SOLUBLE DRUGS

  2013cited by this paper
• LIQUISOLID TECHNIQUE: AN APPROACH FOR ENHANCEMENT OF SOLUBILITY

  2013cited by this paper
• SOLUBILITY AND DISSOLUTION ENHANCEMENT: TECHNOLOGIES AND RESEARCH EMERGED

  2013cited by this paper
• Recent Advances in Nanosponges as Drug Delivery System

  2013cited by this paper
• Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery.

  2013cited by this paper
• A Study on Solubility Enhancement Methods for Poorly Water Soluble Drugs

  2013cited by this paper
• ON SOLUBILITY ENHANCEMENT TECHNIQUES

  2013cited by this paper
• Polymeric Micelles, a Promising Drug Delivery System to Enhance Bioavailability of Poorly Water-Soluble Drugs

  2013cited by this paper
• Self Emulsifying Drug Delivery System: A Tool in Solubility Enhancement of Poorly Soluble Drugs

  2012cited by this paper
• TECHNIQUES FOR SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE DRUGS: AN OVERVIEW

  2012cited by this paper
• Nanosponges: a novel class of drug delivery system--review.

  2012cited by this paper
• Solubility Enhancement of Etoricoxib by Cosolvency Approach

  2012cited by this paper
• Enhancement of solubilization and bioavailability of poorly soluble drugs by physical and chemical modifications : A recent review

  2012cited by this paper
• Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan

  2012cited by this paper
• Enhancement of Dissolution and Anti- inflammatory Activity of Meloxicam by Spherical Agglomeration Technique

  2012cited by this paper
• Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design

  2012cited by this paper
• A REVIEW ON SOLUBILITY ENHANCEMENT TECHNIQUES

  2012cited by this paper
• The use of spray-drying to enhance celecoxib solubility

  2011cited by this paper
• The Liquisolid technique: an overview

  2011cited by this paper
• Nanosuspension: An approach to enhance solubility of drugs

  2011cited by this paper
• New Trends in the Co-crystallization of Active Pharmaceutical Ingredients

  2011cited by this paper

• No citing papers are available for this paper.