REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Nucleic Acids Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/NAR/GKH903PMID 15523096PMCID PMC528789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.

  2004cited by this paper
• Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases.

  2004cited by this paper
• Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.

  2004cited by this paper
• Proliferating Cell Nuclear Antigen-dependent Coordination of the Biological Functions of Human DNA Polymerase ι*

  2004cited by this paper
• Rev1 is essential for DNA damage tolerance and non‐templated immunoglobulin gene mutation in a vertebrate cell line

  2003cited by this paper
• Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis

  2003cited by this paper
• Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta.

  2003cited by this paper
• Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

  2003cited by this paper
• Structure and Enzymatic Properties of a Stable Complex of the Human REV1 and REV7 Proteins*

  2003cited by this paper
• Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene.

  2003cited by this paper
• Localisation of human DNA polymerase kappa to replication foci.

  2002cited by this paper
• Error-prone repair DNA polymerases in prokaryotes and eukaryotes.

  2002cited by this paper
• Cellular roles of DNA polymerase ζ and Rev1 protein

  2002cited by this paper
• Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion.

  2002cited by this paper
• Cellular roles of DNA polymerase zeta and Rev1 protein.

  2002cited by this paper
• Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

  2002cited by this paper
• Biochemical properties of the human REV1 protein

  2002cited by this paper
• Localization of DNA polymerases η and ι to the replication machinery is tightly co‐ordinated in human cells

  2002cited by this paper
• Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.

  2001cited by this paper
• Interactions in the Error-prone Postreplication Repair Proteins hREV1, hREV3, and hREV7*

  2001influential reference
• DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae.

  2001cited by this paper
• Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions.

  2000cited by this paper
• A Human REV7 Homolog That Interacts with the Polymerase ζ Catalytic Subunit hREV3 and the Spindle Assembly Checkpoint Protein hMAD2*

  2000influential reference
• Evidence for a second function for Saccharomyces cerevisiae Rev1p

  2000cited by this paper
• The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.

  2000cited by this paper
• Roles of DNA polymerase zeta and Rev1 protein in eukaryotic mutagenesis and translesion replication.

  2000cited by this paper
• A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans.

  1999cited by this paper
• The human REV1 gene codes for a DNA template-dependent dCMP transferase.

  1999cited by this paper
• Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta.

  1998cited by this paper
• A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.

  1998cited by this paper
• Lack of a cell cycle-dependent strand bias for mutations induced in the HPRT gene by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in excision repair-deficient human cells.

  1991cited by this paper
• Kinds and location of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts.

  1991cited by this paper
• Kinds and location of mutations induced by (±)-7β,8α- dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts

  1991cited by this paper
• Lack of a Cell Cycle-dependent Strand Bias for Mutations Induced in the HPRT Gene by (±)-7β,8α-Dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in Excision Repair-deficient Human Cells

  1991cited by this paper
• Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene.

  1990cited by this paper

• Translesion DNA Synthesis and Carcinogenesis

  2020cites this paper
• Cellular Responses to DNA Damage

  2018cites this paper
• Rad5 coordinates translesion DNA synthesis pathway by recognizing specific DNA structures in saccharomyces cerevisiae

  2018cites this paper
• Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

  2017cites this paper
• Coordination and Substitution of DNA Polymerases in Response to Genomic Obstacles.

  2017cites this paper
• Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase

  2017cites this paper
• Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease.

  2015cites this paper
• TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η

  2014cites this paper
• A non-catalytic function of Rev1 in translesion DNA synthesis and mutagenesis is mediated by its stable interaction with Rad5.

  2013cites this paper
• Different sets of translesion synthesis DNA polymerases protect from genome instability induced by distinct food-derived genotoxins.

  2012influential citation
• Replication of damaged genomes.

  2011cites this paper
• Molecular Chaperone Hsp90 Regulates REV1-Mediated Mutagenesis

  2011cites this paper
• DNA polymerase iota promotes G2/M checkpoint activation and genetic stability after UV-induced DNA damage.

  2011cites this paper
• Temporal gene expression changes induced by a low concentration of benzo[a]pyrene diol epoxide in a normal human cell line.

  2010cites this paper
• The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis

  2010cites this paper
• Translesion Synthesis Polymerases in the Prevention and Promotion of Carcinogenesis

  2010cites this paper
• Cellular Responses to DNA Damage

  2010cites this paper
• REV1 Is Implicated in the Development of Carcinogen-Induced Lung Cancer

  2009cites this paper
• Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

  2009cites this paper
• Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

  2009cites this paper
• Y-family DNA polymerases in mammalian cells

  2009cites this paper
• RAD18 and associated proteins are immobilized in nuclear foci in human cells entering S-phase with ultraviolet light-induced damage.

  2008cites this paper
• RAD18 signals DNA polymerase IOTA to stalled replication forks in cells entering S-phase with DNA damage.

  2008cites this paper
• Green fluorescent protein (GFP) as a direct biosensor for mutation detection: elimination of false-negative errors in target gene expression.

  2008influential citation
• The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase.

  2006cites this paper
• Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses.

  2006cites this paper
• Polη, Polζ and Rev1 together are required for G to T transversion mutations induced by the (+)- and (−)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells

  2006influential citation
• Analyses of ultraviolet‐induced focus formation of hREV1 protein

  2006cites this paper
• Translesion DNA replication proteins as molecular targets for cancer prevention.

  2006cites this paper
• Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans

  2006cites this paper
• REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast.

  2005cites this paper