Cloning and sequencing of a cDNA encoding the rat Bcl-2 protein.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Gene

• Publication date

  1994-03-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0378-1119(94)90561-4PMID 8144041
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bcl-2 and the regulation of programmed cell death

  1994cited by this paper
• Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

  1993cited by this paper
• Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.

  1993cited by this paper
• Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.

  1993cited by this paper
• bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.

  1993cited by this paper
• Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival.

  1993cited by this paper
• Molecular regulation of apoptosis: genetic controls on cell death.

  1993cited by this paper
• Isolation and characterization of the chicken bcl-2 gene: expression in a variety of tissues including lymphoid and neuronal organs in adult and embryo.

  1992cited by this paper

• APG-1252 combined with Cabozantinib inhibits hepatocellular carcinoma by suppressing MEK/ERK and CREB/Bcl-xl pathways.

  2024cites this paper
• Neuroprotective Effects of a Hydrogen Sulfide Donor in Streptozotocin-Induced Diabetic Rats

  2023cites this paper
• Bid is involved in apoptosis induced by Chinese giant salamander iridovirus and contributes to the viral replication in an amphibian cell line.

  2020cites this paper
• Radiation-Generated ROS Induce Apoptosis via Mitochondrial

  2019cites this paper
• ii SYNERGY OF BCL 2 AND HISTONE DEACETYLASE INHIBITION AGAINST LEUKEMIC CELLS FROM CUTANEOUS T-CELL LYMPHOMA PATIENTS

  2018cites this paper
• The Bcl-2 Family Proteins: Insights into Their Mechanism of Action and Therapeutic Potential

  2016cites this paper
• Hydrogen-rich Water Exerting a Protective Effect on Ovarian Reserve Function in a Mouse Model of Immune Premature Ovarian Failure Induced by Zona Pellucida 3

  2016cites this paper
• The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update

  2015cites this paper
• γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells

  2014cites this paper
• The structural biology of BH3-only proteins.

  2014cites this paper
• Effect of prolactin acting on the coeliac ganglion via the superior ovarian nerve on ovarian function in the postpartum lactating and non-lactating rat.

  2013cites this paper
• Structural biology of the Bcl-2 family and its mimicry by viral proteins

  2013cites this paper
• Nerve Sprouting Contributes to Increased Severity of Ventricular Tachyarrhythmias by Upregulating iGluRs in Rats with Healed Myocardial Necrotic Injury

  2012cites this paper
• Apoptosis and Ovarian Follicular Atresia in Mammals

  2012cites this paper
• The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression.

  2010cites this paper
• Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2

  2008influential citation
• NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes.

  2007cites this paper
• Overexpression of RGPR-p117 suppresses apoptotic cell death and its related gene expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells.

  2007cites this paper
• Methylprednisolone and Indomethacin Inhibit Oxidative Stress Mediated Apoptosis in Rat C6 Glioblastoma Cells

  2007cites this paper
• Short Communication Immunohistochemical Analysis of Mci-1 and Bcl-2 Proteins in Normal and Neoplastic Lymph Nodes

  2007cites this paper
• PRAF1: a Golgi complex transmembrane protein that interacts with viruses.

  2006cites this paper
• Estrous cycle dependent changes in expression and distribution of Fas, Fas ligand, Bcl-2, Bax, and pro- and active caspase-3 in the rat ovary.

  2006influential citation
• Topical ER36009, a RARγ-selective retinoid, decreases abdominal white adipose tissue and elicits changes in expression of genes related to adiposity and thermogenesis

  2006cites this paper
• Effects of maternal uninephrectomy on the development of fetal rat kidney: apoptosis and the expression of oncogenes

  2006cites this paper
• Current concepts in apoptosis: The physiological suicide program revisited

  2006cites this paper
• Bax and Bcl-2 expression and TUNEL labeling in lumbar enlargement of neonatal rats after sciatic axotomy and melatonin treatment.

  2006cites this paper
• GH-releasing peptides improve cardiac dysfunction and cachexia and suppress stress-related hormones and cardiomyocyte apoptosis in rats with heart failure.

  2005cites this paper
• Effect of chronic ethanol ingestion and gender on heart left ventricular p53 gene expression.

  2005cites this paper
• Apoptosis in the ovary: molecular mechanisms.

  2005cites this paper
• Overexpression of regucalcin suppresses apoptotic cell death in cloned normal rat kidney proximal tubular epithelial NRK52E cells: Change in apoptosis‐related gene expression

  2005cites this paper
• The lower intestinal tract-specific induction of heme oxygenase-1 by glutamine protects against endotoxemic intestinal injury*

  2005cites this paper
• Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.

  2004cites this paper
• Hexarelin protects rat cardiomyocytes from angiotensin II-induced apoptosis in vitro.

  2004cites this paper
• BCL-2 Translation Is Mediated via Internal Ribosome Entry during Cell Stress*

  2004cites this paper
• Contribution of Glutamine Synthetase to Ammonia-Induced Apoptosis in Gastric Mucosal Cells

  2004cites this paper
• Expression of anti-apoptotic protein, Bcl-2, in liver regeneration after a partial hepatectomy.

  2003cites this paper
• Aging in Sponges

  2003cites this paper
• Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy.

  2003cites this paper
• Apoptotic gene expression in Paget's disease: a possible role for Bcl‐2

  2003cites this paper
• Adenovirus mediated gene transfer of antiapoptotic protein in hepatic ischemia-reperfusion injury: the paradoxical effect of Bcl-2 expression in the reperfused liver.

  2002cites this paper
• Changes in cortical and cerebellar bcl-2 mRNA levels in the developing hydrocephalic rat (LEW-HYR) as measured by a real time quantified RT-PCR.

  2002cites this paper
• Inhibition of apoptosis in rat mesangial cells by tissue inhibitor of metalloproteinase-1.

  2002cites this paper
• SLEEP DEPRIVATION DOES NOT AFFECT INDICES OF NECROSIS OR APOPTOSIS IN RAT BRAIN

  2002cites this paper
• Combined calcium carbimide and ethanol treatment induces high blood acetaldehyde levels, myocardial apoptosis and altered expression of apoptosis-regulating genes in rat.

  2002cites this paper
• A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis.

  2002cites this paper
• Apoptosis and apoptosis-associated gene products related to the response to neoadjuvant chemotherapy for gastric cancer.

  2002cites this paper
• Attenuation of both apoptotic and necrotic actions of cadmium by Bcl-2.

  2001cites this paper
• Sponge Bcl-2 homologous protein (BHP2-GC) confers distinct stress resistance to human HEK-293 cells

  2001cites this paper
• Estrogen and Bcl-2: Gene Induction and Effect of Transgene in Experimental Stroke

  2001cites this paper
• Expression of apoptosis-related genes and proteins in experimental chronic renal scarring.

  2001cites this paper
• bcl-2 Antisense Treatment Prevents Induction of Tolerance to Focal Ischemia in the Rat Brain

  2001cites this paper
• Role of the Fas System in Liver Regeneration after a Partial Hepatectomy in Rats

  2001cites this paper
• Adrenalectomy regulates apoptotic-associated genes in rat hippocampus

  2001cites this paper
• Protective effect of ginsenoside Rg1 on dopamine-induced apoptosis in PC12 cells.

  2001cites this paper
• Altered signaling and regulatory mechanisms of apoptosis in focal and segmental glomerulosclerosis.

  2001cites this paper
• Ethanol infusion increases ANP and p21 gene expression in isolated perfused rat heart.

  2001cites this paper
• Hamster Bcl-2 protein is cleaved in vitro and in cells by caspase-9 and caspase-3.

  2001cites this paper
• SERTOLI CELLS INHIBITED APOPTOSIS OF PACHYTENE SPERMATOCYTES AND ROUND SPERMATIDS

  2001cites this paper
• Acute Pancreatitis Signals Activation of Apoptosis-Associated and Survival Genes in Mice

  2001cites this paper
• Higher order chromatin degradation induced by hydrogen peroxide in glial cells

  2001cites this paper
• Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats.

  2000cites this paper
• Suppression of Endogenous bcl-2 Expression by Antisense Treatment Exacerbates Ischemic Neuronal Death

  2000cites this paper
• Apoptosis in Human Term Placenta

  2000cites this paper
• Increased Calpain Expression Is Associated with Apoptosis in Rat Spinal Cord Injury: Calpain Inhibitor Provides Neuroprotection

  2000cites this paper
• In vivo electroporetic transfer of bcl‐2 antisense oligonucleotide inhibits the development of hepatocellular carcinoma in rats

  2000cites this paper
• Cloning and functional analysis of cDNA encoding the hamster Bcl-2 protein.

  2000cites this paper
• Oxidative stress and Ca2+ influx upregulate calpain and induce apoptosis in PC12 cells.

  2000cites this paper
• E-64-d prevents both calpain upregulation and apoptosis in the lesion and penumbra following spinal cord injury in rats.

  2000cites this paper
• Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells

  2000cites this paper
• Inhibition Of Apoptosis In Cultured Immature Rat Leydig Cells By Human Chorionic Gonadotropin Associated With Bcl-2 Mrna Expression

  2000cites this paper
• Apoptosis regulating proteins as targets of therapy for haematological malignancies.

  1999cites this paper
• Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation.

  1999cites this paper
• Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid

  1999cites this paper
• Apoptosis. Molecules and mechanisms.

  1999cites this paper
• Early detection of apoptosis and fas ligand expression in hepatic graft-versus-host disease after rat small bowel transplantation.

  1999cites this paper
• Delayed oligodendrocyte degeneration induced by brief exposure to hydrogen peroxide

  1999cites this paper
• Analysis of the Fas system and Bcl-2 in rat liver allograft rejection.

  1999cites this paper
• Analysis of the human fibroblast growth factor 4 (FGF4) gene regulatory elements and characterization of the human glasgow rearranged sequence (GRS) gene

  1999cites this paper
• bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis.

  1999cites this paper
• Expression of apoptosis regulatory genes by retinal pericytes after rapid glucose reduction.

  1998cites this paper
• Cell Proliferation and Apoptosis of the Glomerular Epithelial Cells in Rats with Puromycin Aminonucleoside Nephrosis

  1998cites this paper
• Transformation‐dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble fas ligand

  1998cites this paper
• Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus.

  1998cites this paper
• The temporal profile and morphologic features of neuronal death in human stroke resemble those observed in experimental forebrain ischemia: the potential role of apoptosis.

  1998cites this paper
• Differential expression of the estrogen-regulated proto-oncogenes c-fos, c-jun, and bcl-2 and of the tumor-suppressor p53 gene in the male mouse chronically infected with Taenia crassiceps cysticerci

  1998cites this paper
• Sarcophytolide: a new neuroprotective compound from the soft coral Sarcophyton glaucum.

  1998cites this paper
• Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue

  1997cites this paper
• Bcl-2 family proteins and the hormonal control of cell life and death in normalcy and neoplasia.

  1997cites this paper
• Bcl-2 family proteins: strategies for overcoming chemoresistance in cancer.

  1997cites this paper
• Apoptosis-Suppressor Gene bcl-2 Expression after Traumatic Brain Injury in Rats

  1997cites this paper
• Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury.

  1997cites this paper
• Modulation of apoptosis-associated genes bcl-2, bcl-x, and bax during rat liver regeneration.

  1996cites this paper
• Gamma-radiation-induced cell death in the fetal rat brain possesses molecular characteristics of apoptosis and is associated with specific messenger RNA elevations.

  1996cites this paper
• Intestinal cell apoptosis and Bcl-2 expression.

  1996cites this paper
• Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma.

  1996cites this paper
• A cis-acting element in the BCL-2 gene controls expression through translational mechanisms.

  1996cites this paper
• Proapoptotic Protein Bax Heterodimerizes with Bcl-2 and Homodimerizes with Bax via a Novel Domain (BH3) Distinct from BH1 and BH2 (*)

  1996cites this paper
• Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

  1996cites this paper
• Role of apoptosis in acute neurodegenerative disorders

  1996cites this paper
• Structure-function analysis of Bcl-2 family proteins. Regulators of programmed cell death.

  1996cites this paper