Translational Application of Recombinant Humanized Type III Collagen in Facial Rejuvenation: A Randomized Controlled Trial

Zeyu Huang,Ruzhi Zhang,Mi Sheng,T. Tian,Bin Xu,Fang Wang,Danmin Liu

Published 2025 in Journal of Cosmetic Dermatology

ABSTRACT

Skin aging is a common aesthetic concern that drives the demand for new therapeutic strategies. Lyophilized injectable recombinant humanized type III collagen (rhCol III) is an emerging biomaterial with promising regenerative potential; however, clinical data on its efficacy is limited. This study aimed to evaluate the safety and effectiveness of rhCol III in improving the signs of skin aging.

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