Exploring the Protein Landscape of Dormant Mycobacterium tuberculosis Through In Vitro Functional Studies.

No abstract is available for this paper.

• Publication year

  2026

• Venue

  Advances in Experimental Medicine and Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-3-031-96883-9_7PMID 41207941
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Exploring the multifaceted roles of resuscitation-promoting factors in tuberculosis: Implications for diagnosis, vaccine development, and drug targeting

  2025cited by this paper
• Model systems to study Mycobacterium tuberculosis infections: an overview of scientific potential and impediments

  2025cited by this paper
• Genetic determinants of Mycobacterium tuberculosis adaptation and drug efficacy during stationary phase growth

  2025cited by this paper
• Rv0100: An essential acyl carrier protein from M. tuberculosis important in dormancy

  2024cited by this paper
• Rethinking the burden of latent tuberculosis to reprioritize research

  2024cited by this paper
• Gene Regulatory Mechanism of Mycobacterium Tuberculosis during Dormancy

  2024cited by this paper
• Exploring the Genetic Landscape of Mycobacterium tuberculosis: Unlocking the Differences in Between Latent and Active Tuberculosis.

  2024cited by this paper
• Structure of the M. tuberculosis DnaK−GrpE complex reveals how key DnaK roles are controlled

  2024cited by this paper
• WhiB-like proteins: Diversity of structure, function and mechanism.

  2024cited by this paper
• Genome mining of Mycobacterium tuberculosis: targeting SufD as a novel drug candidate through in silico characterization and inhibitor screening.

  2024cited by this paper
• Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis

  2024cited by this paper
• Effect of smoking cessation interventions on abstinence and tuberculosis treatment outcomes among newly diagnosed patients: a randomized controlled trial

  2024cited by this paper
• Oxygen affinities of DosT and DosS sensor kinases with implications for hypoxia adaptation in Mycobacterium tuberculosis

  2024cited by this paper
• Propionate prevents loss of the PDIM virulence lipid in Mycobacterium tuberculosis

  2024cited by this paper
• Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB

  2023cited by this paper
• Outlook for CRISPR-based tuberculosis assays now in their infancy

  2023cited by this paper
• MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance

  2023cited by this paper
• Revolutionizing control strategies against Mycobacterium tuberculosis infection through selected targeting of lipid metabolism

  2023cited by this paper
• Mycobacterium tuberculosis: Pathogenesis and therapeutic targets

  2023cited by this paper
• Structural and Biochemical Characterization of Mycobacterium tuberculosis Zinc SufU-SufS Complex

  2023cited by this paper
• Immune cell interactions in tuberculosis.

  2022cited by this paper
• Transcriptional regulation and drug resistance in Mycobacterium tuberculosis

  2022cited by this paper
• Toxin-Antitoxin Systems Alter Adaptation of Mycobacterium smegmatis to Environmental Stress

  2022cited by this paper
• The Orphan Response Regulator Rv3143 Modulates the Activity of the NADH Dehydrogenase Complex (Nuo) in Mycobacterium tuberculosis via Protein–Protein Interactions

  2022cited by this paper
• Mycobacterium tuberculosis Dormancy: How to Fight a Hidden Danger

  2022cited by this paper
• Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo

  2022cited by this paper
• Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress

  2022cited by this paper
• Mycobacterium tuberculosis dormancy regulon proteins Rv2627c and Rv2628 as Toll like receptor agonist and as potential adjuvant.

  2022cited by this paper
• Tuberculosis: The success tale of less explored dormant Mycobacterium tuberculosis

  2022cited by this paper
• Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe–4S cluster and regulates Fe–S cluster biogenesis for persistence in mice

  2021cited by this paper
• Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis.

  2021cited by this paper
• Endoscopic ultrasonographic diagnosis of pancreatic tuberculosis in immunocompetent patients—A case series from eastern India

  2021cited by this paper
• Shotgun proteomic profiling of dormant, ‘non-culturable’ Mycobacterium tuberculosis

  2021cited by this paper
• Quantitative proteomics reveals that dormancy-related proteins mediate the attenuation in mycobacterium strains

  2021cited by this paper
• Directed Evolution of Propionyl-CoA Carboxylase for Succinate Biosynthesis.

  2021cited by this paper
• Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.

  2021cited by this paper
• Applications of Transcriptomics and Proteomics for Understanding Dormancy and Resuscitation in Mycobacterium tuberculosis

  2021cited by this paper
• RegX3-Mediated Regulation of Methylcitrate Cycle in Mycobacterium smegmatis

  2021cited by this paper
• Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications

  2021cited by this paper
• The knowns and unknowns of latent Mycobacterium tuberculosis infection.

  2021cited by this paper
• Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis

  2021cited by this paper
• Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?

  2021cited by this paper
• The Stress-Responsive Alternative Sigma Factor SigB of Bacillus subtilis and Its Relatives: An Old Friend With New Functions

  2020cited by this paper
• Interaction mechanism of Mycobacterium tuberculosis GroEL2 protein with macrophage Lectin-like, oxidized low-density lipoprotein Receptor-1: An integrated computational and experimental study.

  2020cited by this paper
• One-Year Old Dormant, “Non-culturable” Mycobacterium tuberculosis Preserves Significantly Diverse Protein Profile

  2020cited by this paper
• Inhibiting DosRST as a new approach to tuberculosis therapy

  2020cited by this paper
• Understanding GroEL and DnaK Stress Response Proteins as Antigens for Bacterial Diseases

  2020cited by this paper
• Chaperone-Mediated Stress Sensing in Mycobacterium tuberculosis Enables Fast Activation and Sustained Response

  2020cited by this paper
• Addressing Latent Tuberculosis: New Advances in Mimicking the Disease, Discovering Key Targets, and Designing Hit Compounds

  2020cited by this paper
• Acid Fasting: Modulation of Mycobacterium tuberculosis Metabolism at Acidic pH.

  2019cited by this paper
• The interplay between depression and tuberculosis

  2019cited by this paper
• Surgical treatment of thoracolumbar spinal tuberculosis—a multicentre, retrospective, case-control study

  2019cited by this paper
• Resuscitation of Dormant “Non-culturable” Mycobacterium tuberculosis Is Characterized by Immediate Transcriptional Burst

  2019cited by this paper
• Mycobacterial SigA and SigB Cotranscribe Essential Housekeeping Genes during Exponential Growth

  2019cited by this paper
• MTS1338, A Small Mycobacterium tuberculosis RNA, Regulates Transcriptional Shifts Consistent With Bacterial Adaptation for Entering Into Dormancy and Survival Within Host Macrophages

  2019cited by this paper
• Over-expression of Tgs1 in Mycobacterium marinum enhances virulence in adult zebrafish.

  2019cited by this paper
• Comparative label-free lipidomic analysis of Mycobacterium tuberculosis during dormancy and reactivation

  2019cited by this paper
• Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner

  2019cited by this paper
• Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development

  2019cited by this paper
• Drug targets exploited in Mycobacterium tuberculosis: Pitfalls and promises on the horizon.

  2018cited by this paper
• Host-pathogen redox dynamics modulate Mycobacterium tuberculosis pathogenesis

  2018cited by this paper
• Assessment of tuberculosis contact investigation in Shanghai, China: An 8-year cohort study.

  2018cited by this paper
• MtrA Response Regulator Controls Cell Division and Cell Wall Metabolism and Affects Susceptibility of Mycobacteria to the First Line Antituberculosis Drugs

  2018cited by this paper
• CIRCE element evolved for the coordinated transcriptional regulation of bacterial duplicate groELs.

  2018cited by this paper
• The force-dependent mechanism of DnaK-mediated mechanical folding

  2018cited by this paper
• Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis

  2018cited by this paper
• Plasticity of Mycobacterium tuberculosis NADH dehydrogenases and their role in virulence

  2018cited by this paper
• Mycobacterium tuberculosis WhiB3 maintains redox homeostasis and survival in response to reactive oxygen and nitrogen species

  2018cited by this paper
• China’s tuberculosis epidemic stems from historical expansion of four strains of Mycobacterium tuberculosis

  2018cited by this paper
• Rv1460, a SufR homologue, is a repressor of the suf operon in Mycobacterium tuberculosis

  2018cited by this paper
• The spectrum of tuberculosis of the spine in pediatric age group: a review

  2018cited by this paper
• Small Heat Shock Protein16.3 of Mycobacterium tuberculosis: After Two Decades of Functional Characterization

  2018cited by this paper
• Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

  2017cited by this paper
• Redox-dependent condensation of the mycobacterial nucleoid by WhiB4

  2017cited by this paper
• Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth

  2017cited by this paper
• Mycobacterium tuberculosis GroEL2 Modulates Dendritic Cell Responses

  2017cited by this paper
• Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis

  2017cited by this paper
• Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures

  2017cited by this paper
• Genetic and metabolic regulation of Mycobacterium tuberculosis acid growth arrest

  2017cited by this paper
• Mycobacterial Dormancy Systems and Host Responses in Tuberculosis

  2017cited by this paper
• Detection of anti-HspX antibodies and HspX protein in patient sera for the identification of recent latent infection by Mycobacterium tuberculosis

  2017cited by this paper
• Multiple cytokine responses in discriminating between active tuberculosis and latent tuberculosis infection.

  2017cited by this paper
• The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysis

  2017cited by this paper
• The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence

  2017cited by this paper
• Non-Human Primate Models of Tuberculosis

  2016cited by this paper
• Early diagnosis of spinal tuberculosis.

  2016cited by this paper
• Imaging the NADH:NAD+ Homeostasis for Understanding the Metabolic Response of Mycobacterium to Physiologically Relevant Stresses

  2016cited by this paper
• High Persister Mutants in Mycobacterium tuberculosis

  2016cited by this paper
• Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 Helix

  2016cited by this paper
• Risk of developing active tuberculosis in rheumatoid arthritis patients on adalimumab in Japan.

  2016cited by this paper
• Comprehensive Definition of the SigH Regulon of Mycobacterium tuberculosis Reveals Transcriptional Control of Diverse Stress Responses

  2016cited by this paper
• Inflammatory signaling in human Tuberculosis granulomas is spatially organized

  2016cited by this paper
• Proteomics Analysis of Three Different Strains of Mycobacterium tuberculosis under In vitro Hypoxia and Evaluation of Hypoxia Associated Antigen’s Specific Memory T Cells in Healthy Household Contacts

  2016cited by this paper
• Populations of latent Mycobacterium tuberculosis lack a cell wall: Isolation, visualization, and whole-genome characterization

  2016cited by this paper
• Tuberculosis Caused by Mycobacterium africanum, United States, 2004–2013

  2016cited by this paper
• Mycobacterium tuberculosis gene expression at different stages of hypoxia-induced dormancy and upon resuscitation

  2016cited by this paper
• Reactivation of dormant "non-culturable" Mycobacterium tuberculosis developed in vitro after injection in mice: both the dormancy depth and host genetics influence the outcome.

  2015cited by this paper
• GroEL2 of Mycobacterium tuberculosis Reveals the Importance of Structural Pliability in Chaperonin Function

  2015cited by this paper
• The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems.

  2015cited by this paper
• Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA

  2015cited by this paper

• TZ1391: a computationally designed circular mRNA multi-epitope vaccine candidate against Mycobacterium tuberculosis via TLR3 immunomodulation

  2026cites this paper