Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy

Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline‐directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non‐adherence represents a critical barrier limiting real‐world efficacy of GDMT. This scientific statement aims to provide a comprehensive framework for understanding, measuring, and addressing medication non‐adherence in HF management across diverse healthcare settings. Addressing medication non‐adherence requires systematic, multifaceted approaches targeting individual patient barriers while implementing system‐level interventions. Polypills, digital monitoring platforms, enhanced patient education and empowerment, and multidisciplinary care models represent promising strategies to optimize therapeutic adherence and improve clinical outcomes in HF management.

• Publication year

  2025

• Venue

  European Journal of Heart Failure

• Publication date

  2025-11-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/ejhf.70090PMID 41208145PMCID 12803664
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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