Measures of Comorbidities and Frailty in Multiple Sclerosis—Systematic Review on Evidence and Applicability of Utilized Scoring Systems in Clinical Routine and Real‐World Data

M. L. Aicher,Fabian Föttinger,R. Hoepner,Andrew Chan,Thomas Berger,G. Bsteh

Published 2025 in European Journal of Neurology

ABSTRACT

In multiple sclerosis (MS), comorbidities and frailty are receiving increasing attention influencing disease course, treatment and quality of life. The objective of this literature review is to evaluate the evidence, strengths and weaknesses of assessment tools for comorbidities and frailty in people with MS (pwMS).

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