JPET EARLY-CAREER MINIREVIEW INITIATIVE — MINIREVIEW Mini-review: Human N-acetyltransferase genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity

No abstract is available for this paper.

• Publication year

  year unknown

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Diet, glutathione S-transferases M1 and T1 gene polymorphisms and cancer risk: a systematic review of observational studies

  2025cited by this paper
• Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline

  2024cited by this paper
• The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

  2023cited by this paper
• Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

  2023cited by this paper
• Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

  2023cited by this paper
• Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens

  2022cited by this paper
• Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes

  2022cited by this paper
• Expression and prognostic value of SULT1A2 in bladder cancer

  2021cited by this paper
• Chemical Risk Factors of Primary Liver Cancer: A Short Comment [Letter]

  2021cited by this paper
• Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

  2021cited by this paper
• Metabolism and biomarkers of heterocyclic aromatic amines in humans

  2021cited by this paper
• Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways.

  2021cited by this paper
• Bladder Cancer: Overview, Epidemiology, Initial Presentation and Diagnosis

  2020cited by this paper
• 2-naphthylamine toxicity.

  2020cited by this paper
• Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

  2020cited by this paper
• 4-Aminobiphenyl inhibits the DNA homologous recombination repair in human liver cells: The role of miR-630 in downregulating RAD18 and MCM8.

  2020cited by this paper
• Discovery of breast cancer risk genes and establishment of a prediction model based on estrogen metabolism regulation

  2020cited by this paper
• Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen.

  2019cited by this paper
• DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging.

  2019cited by this paper
• DNA-damaging activities of twenty-four structurally diverse unsubstituted and substituted cyclic compounds in embryo-fetal chicken livers.

  2019cited by this paper
• N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes

  2019cited by this paper
• Role of PI3K/Akt pathway in Benzidine-induced proliferation in SV-40 immortalized human uroepithelial cell

  2019cited by this paper
• Lipoxygenase Protein Expression and Its Effect on Oxidative Stress Caused by Benzidine in Normal Human Urothelial Cell Lines

  2019cited by this paper
• Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation.

  2018cited by this paper
• A review of HPRT and its emerging role in cancer

  2018cited by this paper
• British rubber and cable industry cohort: 49-year mortality follow-up

  2018cited by this paper
• Occupational exposure to textile dust and lung cancer risk: Results from the ICARE Study

  2018cited by this paper
• Carcinogens and DNA damage

  2018cited by this paper
• Comparison of Bladder Carcinogens in the Urine of E-cigarette Users Versus Non E-cigarette Using Controls

  2018cited by this paper
• gamma-H2AX: Can it be established as a classical cancer prognostic factor?

  2017cited by this paper
• Urinary bladder cancer risk factors in an area of former coal, iron, and steel industries in Germany

  2017cited by this paper
• Acute exposure to DEHP metabolite, MEHP cause genotoxicity, mutagenesis and carcinogenicity in mammalian Chinese hamster ovary cells

  2017cited by this paper
• Risk of Lung Cancer in Workers Exposed to Benzidine and/or Beta-Naphthylamine: A Systematic Review and Meta-Analysis

  2016influential reference
• Effect of CYP3A4 genetic polymorphisms on the genotoxicity of 4,4′-methylene-bis(2-chloroaniline)-exposed workers

  2016cited by this paper
• Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens

  2016cited by this paper
• Quantitative analysis of the association between sulfotransferase isoform 1A1 polymorphism and risk of urothelial carcinoma.

  2015cited by this paper
• Increased risk of lung cancer associated with occupational exposure to benzidine and/or beta-naphthylamine

  2015cited by this paper
• N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.

  2015cited by this paper
• Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

  2014cited by this paper
• Arylamine N‐acetyltransferases: a structural perspective

  2013cited by this paper
• Model and mechanism: N-hydroxylation of primary aromatic amines by cytochrome P450.

  2013cited by this paper
• Rapid and intermediate N-acetylators are less susceptible to oxidative damage among 4,4'-methylenebis(2-chloroaniline) (MBOCA)-exposed workers.

  2013cited by this paper
• Bladder cancer, a review of the environmental risk factors

  2012influential reference
• Mammalian cell HPRT gene mutation assay: test methods.

  2012cited by this paper
• Genotoxicity of 2,6- and 3,5-dimethylaniline in cultured mammalian cells: the role of reactive oxygen species.

  2012cited by this paper
• Roles of human sulfotransferases in genotoxicity of carcinogens using genetically engineered umu test strains

  2012cited by this paper
• Phenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-Dependent

  2012cited by this paper
• Occupational contact allergy caused by benzidine in three tannery workers

  2012cited by this paper
• GSTM1 null and NAT2 slow acetylation genotypes, smoking intensity and bladder cancer risk: results from the New England bladder cancer study and NAT2 meta-analysis.

  2011cited by this paper
• Induction of DNA damage signaling genes in benzidine‐treated HepG2 cells

  2011cited by this paper
• Bladder cancer mortality of workers exposed to aromatic amines: a 58-year follow-up.

  2010cited by this paper
• H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy

  2010cited by this paper
• Metabolic influences for mutation induction curves after exposure to Sudan-1 and para red.

  2010cited by this paper
• Reactive oxygen species in cancer

  2010cited by this paper
• Codominant Expression of N-Acetylation and O-Acetylation Activities Catalyzed by N-Acetyltransferase 2 in Human Hepatocytes

  2010cited by this paper
• Monocyclic aromatic amines as potential human carcinogens: old is new again

  2009influential reference
• Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.

  2009cited by this paper
• Genetic polymorphisms in CYP1A1, CYP1B1, COMT, GSTP1 and NAT2 genes and association with bladder cancer risk in a French cohort.

  2009cited by this paper
• Genetic Polymorphism in N-Acetyltransferase (NAT): Population Distribution of NAT1 and NAT2 Activity

  2009cited by this paper
• N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.

  2009cited by this paper
• Aromatic DNA adducts and polymorphisms in metabolic genes in healthy adults: findings from the EPIC-Spain cohort.

  2009cited by this paper
• Benzidine-based dyes: effects of industrial practices, regulations, and world trade on the biological stains market

  2009cited by this paper
• Cancer incidence and exposure to 4,4'-methylene-bis-ortho-chloroaniline (MbOCA).

  2009cited by this paper
• Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: a literature-based systematic HuGE review and meta-analysis.

  2008cited by this paper
• Arylamine N-acetyltransferases: from structure to function.

  2008cited by this paper
• Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells.

  2007cited by this paper
• Identification of adducts formed by reaction of N-acetoxy-3,5-dimethylaniline with DNA.

  2007cited by this paper
• Evidence that 4‐aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species

  2007cited by this paper
• Structural Basis of Substrate-binding Specificity of Human Arylamine N-Acetyltransferases*

  2007cited by this paper
• Reactive oxygen species: role in the development of cancer and various chronic conditions

  2006cited by this paper
• The genetic and environmental factors involved in benzidine metabolism and bladder carcinogenesis in exposed workers.

  2006influential reference
• DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice.

  2006cited by this paper
• Review of the Salmonella typhimurium mutagenicity of benzidine, benzidine analogues, and benzidine-based dyes.

  2006cited by this paper
• Unlabeled hemoglobin adducts of 4,4′-methylenebis (2-chloroaniline) in rats and guinea pigs

  2006cited by this paper
• Glutathione S-transferase genotypes and cancer risk.

  2005cited by this paper
• Arylamine N-Acetyltransferases: What We Learn from Genes and Genomes

  2005cited by this paper
• Occupational Bladder Cancer in a 4,4′-Methylenebis(2-chloroaniline) (MBOCA)-Exposed Worker

  2005cited by this paper
• NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses.

  2005cited by this paper
• Comparative metabolic activation of benzidine and N-acetylbenzidine by prostaglandin H synthase.

  2004cited by this paper
• Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system.

  2004cited by this paper
• Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer.

  2004cited by this paper
• Mutagenicity of textile dye products

  2004cited by this paper
• Bladder tumours in rubber workers: a factory study 1946-1995.

  2004cited by this paper
• Distinct mechanisms lead to HPRT gene mutations in leukemic cells

  2004cited by this paper
• GSTP1 A1578G (Ile105Val) polymorphism in benzidine-exposed workers: an association with cytological grading of exfoliated urothelial cells.

  2003cited by this paper
• Urothelial cell DNA adducts in rubber workers †

  2002cited by this paper
• Differences in N-acetylation genotypes between Caucasians and Black South Africans: implications for cancer prevention.

  2002cited by this paper
• Re‐evaluation of the latent period of bladder cancer in dyestuff‐plant workers in Japan

  2001cited by this paper
• Localization of N-acetyltransferases NAT1 and NAT2 in human tissues.

  2000cited by this paper
• Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.

  2000cited by this paper
• Arylamine N-acetyltransferase 1 (NAT1) genotypes in a Lebanese population.

  2000cited by this paper
• Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients.

  2000cited by this paper
• N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.

  2000cited by this paper
• Relationship between NAT1 genotype and phenotype in a Japanese population.

  2000cited by this paper
• An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes.

  2000cited by this paper
• Hprt mutant frequency and molecular analysis of Hprt mutations in rats treated with mutagenic carcinogens.

  1999cited by this paper
• Epidemiology of Bladder Cancer

  1999cited by this paper
• Micronuclei in peripheral lymphocytes and exfoliated urothelial cells of workers exposed to 4,4'-methylenebis-(2-chloroaniline) (MOCA).

  1999cited by this paper
• Detection of mutations and polymorphism of N-acetyltransferase 1 gene in Indian, Malay and Chinese populations.

  1998cited by this paper
• Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk.

  1998cited by this paper

• No citing papers are available for this paper.