Performance of the Self‐Controlled Case Series With Active Comparators for Drug Safety Signal Detection Using Merative MarketScan Research Databases

Despite testing of epidemiological methods in US Claims databases for signal detection, such data sources have not become a routine capability. The Self Controlled Case Series (SCCS) is one of the most promising methods for drug safety signal detection using Real World Data, and incorporating active comparators could potentially improve its performance by addressing confounding by indication.

• Publication year

  2025

• Venue

  Pharmacoepidemiology and Drug Safety

• Publication date

  2025-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/pds.70250PMID 41216769PMCID 12603968
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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