Unveiling the environmental threat of acetaminophen: ecotoxicology, microbial remediation, and molecular modelling insights

No abstract is available for this paper.

• Publication year

  2025

• Venue

  Environmental Monitoring & Assessment

• Publication date

  2025-11-12

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1007/s10661-025-14744-6PMID 41222815
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Novel Sesbania wood-based activated carbon for paracetamol removal: integrating batch adsorption, fixed-bed studies, and machine learning

  2025cited by this paper
• Environmental Toxicology As an Interdisciplinary Area of Science: Origins and Contemporary Experience (Review)

  2025cited by this paper
• The universal accumulation of p-aminophenol during the microbial degradation of analgesic and antipyretic acetaminophen in WWTPs: a novel metagenomic perspective

  2025influential reference
• Luffa cylindrica-based immobilization: Effects on metabolic activity and paracetamol degradation by Pseudomonas moorei KB4

  2025cited by this paper
• Synthesis and characterization of fungal and luffa sponge biocomposite sorbent for the removal of acetaminophen

  2025influential reference
• Occurrence and removal of pharmaceuticals in hospital wastewater and the contribution to wastewater treatment plants.

  2025cited by this paper
• DFT Analyses of arsylsemicarbazone group as functional compound for application as excellent fluorescent probes and medicament: study on virtual screening through molecular docking

  2024cited by this paper
• Molecular Simulation Studies of Pharmaceutical Pollutant Removal (Rosuvastatin and Simvastatin) Using Novel Modified-MOF Nanostructures (UIO-66, UIO-66/Chitosan, and UIO-66/Oxidized Chitosan).

  2024influential reference
• Biodegradation of acetaminophen: Microcosm centric genomic-proteomic-metabolomics evidences.

  2024cited by this paper
• Photocatalytic degradation of drugs and dyes using a maching learning approach

  2024influential reference
• Environmental concentrations of acetaminophen and its metabolites promote the spread of antibiotic resistance genes through pheromone signaling pathway

  2024cited by this paper
• Decomposition of non-steroidal anti-inflammatory drugs by activated sludge supported by biopreparation in sequencing batch reactor.

  2024influential reference
• Paracetamol Use and COVID-19 Clinical Outcomes: A Meta-Analysis

  2024cited by this paper
• Unveiling the analgesic and antipyretic drug acetaminophen catabolic mechanism in Pseudomonas taiwanensis AP-1.

  2024cited by this paper
• Batch studies on the biodegradation of paracetamol and 1,4-hydroquinone by novel bacterial strains isolated from extreme environmental samples and the identification of candidate catabolic genes

  2024cited by this paper
• Advancements in molecular simulation for understanding pharmaceutical pollutant Adsorption: A State-of-the-Art review

  2024influential reference
• Combining predictive and analytical methods to elucidate pharmaceutical biotransformation in activated sludge.

  2023influential reference
• Role of fungi in bioremediation of emerging pollutants

  2023cited by this paper
• Acetaminophen-traces bioremediation with novel phenotypically and genotypically characterized 2 Streptomyces strains using chemo-informatics, in vivo, and in vitro experiments for cytotoxicity and biological activity

  2023cited by this paper
• Tracing COVID-19 drugs in the environment: Are we focusing on the right environmental compartment?

  2023cited by this paper
• Characterization and biodegradation of paracetamol by Bacillus pumilus strain PYP2

  2023cited by this paper
• Microbial approaches for pharmaceutical wastewater recycling and management for sustainable development: A multicomponent approach.

  2023cited by this paper
• Transcriptomic Analysis of Acetaminophen Biodegradation by Penicillium chrysogenum var. halophenolicum and Insights into Energy and Stress Response Pathways

  2023influential reference
• Egyptian perspectives on potential risk of paracetamol/acetaminophen-induced toxicities: Lessons learnt during COVID-19 pandemic

  2022cited by this paper
• Microbial Cell Factories For the Management of Pharmaceutical Micropollutants

  2022cited by this paper
• Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila

  2022cited by this paper
• Intracellular Quantum Sensing of Free-Radical Generation Induced by Acetaminophen (APAP) in the Cytosol, in Mitochondria and the Nucleus of Macrophages

  2022cited by this paper
• Batch Studies on the Biodegradation Potential of Paracetamol, Fluoxetine and 17α-ethinylestradiol by the Micrococcus yunnanensis Strain TJPT4 Recovered from Marine Organisms

  2022cited by this paper
• RONS and Oxidative Stress: An Overview of Basic Concepts

  2022cited by this paper
• Densification of waste biomass for manufacturing solid biofuel pellets: a review

  2022cited by this paper
• Paracetamol biodegradation by Pseudomonas strain PrS10 isolated from pharmaceutical effluents

  2022cited by this paper
• A review on the degradation of acetaminophen by advanced oxidation process: pathway, by-products, biotoxicity, and density functional theory calculation

  2022cited by this paper
• Assessment of Uptake, Accumulation and Degradation of Paracetamol in Spinach (Spinacia oleracea L.) under Controlled Laboratory Conditions

  2022cited by this paper
• Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates

  2022cited by this paper
• Optimization of White-Rot Fungi Mycelial Culture Components for Bioremediation of Pharmaceutical-Derived Pollutants

  2022cited by this paper
• Isolation and identification of acetaminophen degrading strain Shinella sp. HZA2

  2022cited by this paper
• A review on bioremediation approach for heavy metal detoxification and accumulation in plants.

  2022cited by this paper
• COVID-19 drugs in aquatic systems: a review

  2022cited by this paper
• Importance and applications of biofilm in microbe-assisted bioremediation

  2022cited by this paper
• AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings

  2021cited by this paper
• Biodegradation of Paracetamol by Some Gram-Positive Bacterial Isolates

  2021cited by this paper
• Biodegradation of acetaminophen and its main by-product 4-aminophenol by Trichoderma harzianum versus mixed biofilm of Trichoderma harzianum/Pseudomonas fluorescens in a fungal microbial fuel cell

  2021cited by this paper
• Pharmaceutical compounds used in the COVID-19 pandemic: A review of their presence in water and treatment techniques for their elimination

  2021cited by this paper
• Patterns of pharmaceuticals use during the first wave of COVID-19 pandemic in Athens, Greece as revealed by wastewater-based epidemiology

  2021cited by this paper
• Mycoremediation of acetaminophen: Culture parameter optimization to improve efficacy.

  2021cited by this paper
• A Computational Approach on Acetaminophen Drug using Degree-Based Topological Indices and M-Polynomials

  2021cited by this paper
• Characterization, optimization and kinetics study of acetaminophen degradation by Bacillus drentensis strain S1 and waste water degradation analysis

  2020cited by this paper
• Underlying mechanisms of reactive oxygen species and oxidative stress photoinduced by graphene and its surface-functionalized derivatives

  2020influential reference
• Prostaglandins prevent acetaminophen induced embryo toxicity in zebrafish (Danio rerio).

  2020cited by this paper
• Paracetamol affects the expression of detoxification- and reproduction-related genes and alters the life traits of Daphnia magna

  2020cited by this paper
• Biodegradation and Kinetic Analysis of Acetaminophen with Co-culture of Bacterial Strains Isolated from Sewage Wastewater

  2020cited by this paper
• Mycoremediation: Expunging environmental pollutants

  2020cited by this paper
• Toxicity of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) acetylsalicylic acid, paracetamol, diclofenac, ibuprofen and naproxen towards freshwater invertebrates: A review.

  2020cited by this paper
• Characterisation and bioremediation of wastewater: A review exploring bioremediation as a sustainable technique for pharmaceutical wastewater

  2020cited by this paper
• Computational Fluid Dynamics

  2020cited by this paper
• Occurrence, seasonal variations, and ecological risk of pharmaceuticals and personal care products in River Ganges at two holy cities of India.

  2020cited by this paper
• Synthesis, biological activity and POM/DFT/docking analyses of annulated pyrano[2,3-d]pyrimidine derivatives: Identification of antibacterial and antitumor pharmacophore sites.

  2020cited by this paper
• High Concentrations of Pharmaceuticals in a Nigerian River Catchment

  2020influential reference
• Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

  2020cited by this paper
• DFT calculations on molecular structures, HOMO–LUMO study, reactivity descriptors and spectral analyses of newly synthesized diorganotin(IV) 2‐chloridophenylacetohydroxamate complexes

  2019cited by this paper
• Phylogenetic origins for severe acetaminophen toxicity in snake species compared to other vertebrate taxa.

  2019cited by this paper
• Characterization of an arylamidase from a newly isolated propanil-transforming strain of Ochrobactrum sp. PP-2.

  2019cited by this paper
• Biosorption of cadmium and nickel by pretreated Aspergillus spp. biomass

  2019cited by this paper
• Chemical characterization and phytotoxicity assessment of peri-urban soils using seed germination and root elongation tests

  2019cited by this paper
• Molecular docking, dynamics simulation and ADMET prediction of Acetaminophen and its modified derivatives based on quantum calculations

  2019cited by this paper
• Putative Role of Flavobacterium, Dokdonella and Methylophilus Strains in Paracetamol Biodegradation

  2018cited by this paper
• Paracetamol - toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring degradation pathway.

  2018influential reference
• Fate of pharmaceutical active compounds (PhACs) from River Yamuna, India: An ecotoxicological risk assessment approach.

  2018cited by this paper
• Uptake and toxicological effects of pharmaceutical active compounds on maize

  2018cited by this paper
• Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria

  2018influential reference
• Analytical approaches for the determination of personal care products and evaluation of their occurrence in marine organisms.

  2018cited by this paper
• Does the presence of caffeine in the marine environment represent an environmental risk? A regional and global study.

  2018cited by this paper
• Brown Tree Snakes Methods and Approaches for Control

  2018cited by this paper
• Mass loading and removal of pharmaceuticals and personal care products including psychoactives, antihypertensives, and antibiotics in two sewage treatment plants in southern India.

  2017influential reference
• The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

  2017influential reference
• A review on characterization and bioremediation of pharmaceutical industries’ wastewater: an Indian perspective

  2017cited by this paper
• Occurrence and removal of pharmaceuticals in four full-scale constructed wetlands in the Czech Republic – the first year of monitoring

  2017cited by this paper
• Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment

  2017cited by this paper
• Complete Genome Sequence of Sphingobium baderi DE-13, an Alkyl-Substituted Aniline-Mineralizing Bacterium

  2017cited by this paper
• Antibiotics impact plant traits, even at small concentrations

  2017cited by this paper
• Evaluation of the degradation of acetaminophen by the filamentous fungus Scedosporium dehoogii using carbon-based modified electrodes

  2016cited by this paper
• Possible ecological risk of two pharmaceuticals diclofenac and paracetamol demonstrated on a model plant Lemna minor.

  2016influential reference
• Occurrence and fate of pharmaceuticals in WWTPs in India and comparison with a similar study in the United States.

  2016influential reference
• Using aquatic fungi for pharmaceutical bioremediation: Uptake of acetaminophen by Mucor hiemalis does not result in an enzymatic oxidative stress response.

  2016influential reference
• Occurrence and removal of organic micropollutants: An overview of the watch list of EU Decision 2015/495.

  2016cited by this paper
• Priority Substances and Emerging Organic Pollutants in Portuguese Aquatic Environment: A Review.

  2016cited by this paper
• Offline solid-phase extraction for preconcentration of pharmaceuticals and personal care products in environmental water and their simultaneous determination using the reversed phase high-performance liquid chromatography method

  2016cited by this paper
• Pharmaceuticals in the environment: biodegradation and effects on natural microbial communities. A review.

  2015cited by this paper
• Plant uptake of pharmaceutical and personal care products from recycled water and biosolids: a review.

  2015cited by this paper
• Pharmaceutical residues in water and sediment of Msunduzi River, KwaZulu-Natal, South Africa.

  2015cited by this paper
• Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726

  2014cited by this paper
• Medicines discarded in household garbage: analysis of a pharmaceutical waste sample in Vienna

  2014cited by this paper
• Degradation and transformation products of acetaminophen in soil.

  2014cited by this paper
• Fate and Uptake of Pharmaceuticals in Soil–Plant Systems

  2014cited by this paper
• UvA-DARE ( Digital Academic Repository ) Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis

  2014cited by this paper
• Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants.

  2014cited by this paper
• A national survey of trace organic contaminants in Australian rivers.

  2014cited by this paper
• Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726

  2014cited by this paper
• Effect of physical, chemical and biological treatment on the removal of five pharmaceuticals from domestic wastewater in laboratory-scale reactors and full-scale plant

  2014cited by this paper
• Biochemical effects of acetaminophen in aquatic species: edible clams Venerupis decussata and Venerupis philippinarum

  2013cited by this paper

• Next-generation photo-Fenton treatment using MIL-100(Fe) synthesized through a green route for sustainable remediation of pharmaceutical wastewater

  2026cites this paper