Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Virchows Archiv

• Publication date

  2010-03-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00428-010-0898-4PMID 20300772
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hybrid renal cell carcinomas containing histopathologic features of chromophobe renal cell carcinomas and oncocytomas have excellent oncologic outcomes.

  2010cited by this paper
• Early onset of renal cancer in a family with Birt–Hogg–Dubé syndrome

  2009cited by this paper
• Hybrid tumour ‘oncocytoma‐chromophobe renal cell carcinoma’ of the kidney: a report of seven sporadic cases

  2009cited by this paper
• Novel intronic germline FLCN gene mutation in a patient with multiple ipsilateral renal neoplasms.

  2009cited by this paper
• Birt–Hogg–Dubé syndrome with clear‐cell and oncocytic renal tumour and trichoblastoma associated with a novel FLCN mutation

  2009cited by this paper
• Chromophobe renal cell carcinoma: useful diagnostic application of imprint cytology and fluorescence in situ hybridization of chromosomes 10 and 21 in two cases of typical and eosinophilic variants

  2008cited by this paper
• Interphase cytogenetic analysis with centromeric probes for chromosomes 1, 2, 6, 10, and 17 in 11 tumors from a patient with bilateral renal oncocytosis

  2008cited by this paper
• Renal oncocytoma with and without intravascular extension into the branches of renal vein have the same morphological, immunohistochemical and genetic features

  2008cited by this paper
• Identification and characterization of Birt–Hogg–Dubé associated renal carcinoma

  2007cited by this paper
• Oncocytic papillary renal cell carcinoma: a clinicopathologic, immunohistochemical, ultrastructural, and interphase cytogenetic study of 12 cases.

  2006cited by this paper
• Birt-Hogg-Dubé syndrome: clinicopathologic findings and genetic alterations.

  2006cited by this paper
• Renal Oncocytoma

  2006cited by this paper
• Adult Papillary Renal Tumor With Oncocytic Cells: Clinicopathologic, Immunohistochemical, and Cytogenetic Features of 10 Cases

  2005cited by this paper
• Hybrid chromophobe renal cell neoplasm.

  2005cited by this paper
• Renal oncocytosis

  2005cited by this paper
• Evaluation and management of renal tumors in the Birt-Hogg-Dubé syndrome.

  2005influential reference
• Eosinophilic and classic chromophobe renal cell carcinomas have similar frequent losses of multiple chromosomes from among chromosomes 1, 2, 6, 10, and 17, and this pattern of genetic abnormality is not present in renal oncocytoma

  2005cited by this paper
• Renal Tumors in the Birt-Hogg-Dubé Syndrome

  2002influential reference
• Renal oncocytosis: a morphologic study of fourteen cases.

  1999cited by this paper
• Lack of genetic changes at specific genomic sites separates renal oncocytomas from renal cell carcinomas

  1998cited by this paper
• Comparative genomic hybridization for genetic analysis of renal oncocytomas

  1996cited by this paper
• Renal chromophobe cell carcinoma: limitations of paraffin-embedded tissue.

  1993cited by this paper
• Renal oncocytoma. A phenotypic and genotypic entity of renal parenchymal tumors.

  1989cited by this paper

• GPNMB Expression Identifies FLCN-Associated Eosinophilic Renal Tumors With Heterogeneous Clinicopathologic Spectrum and Gene Expression Profiles.

  2025cites this paper
• Molecular and therapeutic landscape of non-clear cell renal carcinoma

  2025cites this paper
• Conventional FLCN-mutated tumor: a retrospective study of 5 cases with emphasis on diagnostic challenges.

  2025cites this paper
• What Is New in Pathologic Diagnosis and Classification of the Common Renal Cell Neoplasms?

  2024cites this paper
• Molecular Pathogenesis of Renal Neoplasms in Patients with Birt–Hogg–Dubé Syndrome

  2024cites this paper
• Low grade oncocytic renal tumor (LOT): Clinicopathological characterization of 13 cases.

  2024cites this paper
• A rare case of sporadic renal hybrid oncocytic/chromophobe tumor in a young woman.

  2024cites this paper
• Kidney Tumor Friends: A 15-Year History and Legacy of Ondřej Hes, MD, PhD (1968-2022)

  2023cites this paper
• Do we need an updated classification of oncocytic renal tumors?

  2022cites this paper
• The value of sestamibi single-photon emission computed tomography/computed tomography in differentiating and staging renal cell carcinomas: A systematic review

  2022cites this paper
• Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma

  2022cites this paper
• Heterozygous germline FLCN mutation in Birt–Hogg–Dubé syndrome with bilateral renal hybrid oncocytic/chromophobe tumor and unilateral renal chromophobe cell carcinoma: a case report

  2022cites this paper
• Low-Grade Oncocytic Tumor of Kidney: A Distinct Emerging Entity in Renal Oncocytic Neoplasms with Diagnostic Challenge in An Old Female: A Case Report

  2022cites this paper
• LOT and HOT … or not. The proliferation of clinically insignificant and poorly characterised types of renal neoplasia.

  2022cites this paper
• Renal oncocytoma: a challenging diagnosis

  2022influential citation
• WHO 2022 landscape of papillary and chromophobe renal cell carcinoma

  2022cites this paper
• Low-Grade Oncocytic Renal Tumor With Massive Liver Metastasis: Do Not Trust a Negative CK7 and Misdiagnose Oncocytoma: A Cautionary Tale and Current Classification of Oncocytic Renal Tumors

  2022cites this paper
• Renal Oncocytoma: The Diagnostic Challenge to Unmask the Double of Renal Cancer

  2022influential citation
• Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases

  2021cites this paper
• Renal oncocytoma with prominent xanthomatous reaction. A rare histopathological variant of oncocytoma

  2021cites this paper
• Renal cell carcinomas with tubulopapillary architecture and oncocytic cells: Molecular analysis of 39 difficult tumors to classify.

  2021cites this paper
• Morphological and Molecular Study of Hybrid Oncocytic/Chromophobe Tumor of the Kidney Associated with Sporadic Renal Oncocytosis and Chronic B-Cell Lymphocytic Leukemia: The Possible Contribution of Lymphoma to Renal Oncocytosis

  2021cites this paper
• Key Renal Neoplasms With a Female Predominance.

  2021cites this paper
• Onkozytäre Tumoren der Niere – neue Differenzialdiagnosen

  2021cites this paper
• Histologische Subtypen des Nierenzellkarzinoms

  2021cites this paper
• Low-Grade Oncocytic Tumor: Report of Two Cases of An Emerging Entity in the Spectrum of Oncocytic Renal Neoplasms

  2021cites this paper
• Oncocytic renal neoplasms with diffuse keratin 7 immunohistochemistry harbor frequent alterations in the mammalian target of rapamycin pathway

  2021cites this paper
• Genitourinary Neoplasms

  2021cites this paper
• Cytomorphology, immunoprofile, and management of renal oncocytic neoplasms

  2020cites this paper
• [Evolution of followed renal oncocytomas].

  2020cites this paper
• ESC, ALK, HOT and LOT: Three Letter Acronyms of Emerging Renal Entities Knocking on the Door of the WHO Classification

  2020cites this paper
• Kidney Cancer: Recent Advances in Surgical and Molecular Pathology

  2020influential citation
• DIFFERENTIATION OF RENAL ONCOCYTOMA FROM RENAL CELL CARCINOMA BY MEANS OF 99MTC-SESTAMIBI SPECT/CT

  2020cites this paper
• Towards a new WHO classification of renal cell tumor: what the clinician needs to know—a narrative review

  2020influential citation
• In Situ Metabolomics Expands the Spectrum of Renal Tumours Positive on 99mTc-sestamibi Single Photon Emission Computed Tomography/Computed Tomography Examination

  2020cites this paper
• The Role of Genetic Analysis in Correct Diagnosis of Eosinophilic Variant of Chromophobe Renal Cell Carcinoma

  2020cites this paper
• Chromophobe renal cell carcinoma: current and controversial issues.

  2020cites this paper
• Spontaneous rupture of a hybrid oncocytic chromophobe tumor: A case report

  2020cites this paper
• Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new evidence from China

  2020cites this paper
• FOXI1 expression in chromophobe renal cell carcinoma and renal oncocytoma: a study of The Cancer Genome Atlas transcriptome–based outlier mining and immunohistochemistry

  2020cites this paper
• CD117 Is a Specific Marker of Intraductal Papillary Mucinous Neoplasms (IPMN) of the Pancreas, Oncocytic Subtype

  2020cites this paper
• Sporadic Oncocytic Tumors with Features Intermediate between Oncocytoma and Chromophobe Renal Cell Carcinoma: Comprehensive Clinico-Pathological and Genomic Profiling

  2020cites this paper
• [The morphological characteristics and immunophenotype of renal cell carcinomas with eosinophilic cytoplasm].

  2020cites this paper
• Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers: III: Molecular Pathology of Kidney Cancer.

  2020cites this paper
• Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma

  2019cites this paper
• Classification of solid renal tumor with oncocytic/eosinophilic cytoplasm: is hybrid oncocytic/chromophobe renal tumor a subtype of oncocytoma, chromophobe renal cell carcinoma, or a distinct tumor entity?

  2019cites this paper
• Hereditary Syndromes Associated with Kidney Tumors

  2019cites this paper
• Imagerie diagnostique des tumeurs bénignes du rein de l’adulte

  2019cites this paper
• Major Subtypes of Renal Cell Carcinoma

  2019cites this paper
• Sporadic renal hybrid oncocytic/chromophobe tumor in a young man

  2019cites this paper
• New and emerging renal entities: a perspective post‐WHO 2016 classification

  2019cites this paper
• Nonneoplastic Changes in Nephrectomy Specimens for Tumors

  2019cites this paper
• Combined Immunohistochemistry for the “Three 7” Markers (CK7, CD117, and Claudin-7) Is Useful in the Diagnosis of Chromophobe Renal Cell Carcinoma and for the Exclusion of Mimics: Diagnostic Experience from a Single Institution

  2019cites this paper
• Is it "hybrid" or "intermediate"?-more than just a semantic issue in oncocytic renal cell tumors.

  2019cites this paper
• Onkocitni tumori bubrega

  2019cites this paper
• Low‐grade oncocytic tumour of kidney (CD117‐negative, cytokeratin 7‐positive): a distinct entity?

  2019cites this paper
• Renal Mass Biopsy

  2019cites this paper
• Incidence and histologic features of mixed renal tumors

  2018cites this paper
• Kidney and Adrenal Gland

  2018cites this paper
• Morphological clues to the appropriate recognition of hereditary renal neoplasms.

  2018cites this paper
• Hybrid Oncocitic/Chromophobe Renal Cell Carcinoma

  2018cites this paper
• Cytogenetic and immunohistochemical study of 42 pigmented microcystic chromophobe renal cell carcinoma (PMChRCC)

  2018cites this paper
• “High-grade oncocytic renal tumor”: morphologic, immunohistochemical, and molecular genetic study of 14 cases

  2018cites this paper
• Hybrid oncocytic/chromophobe renal cell tumor: An integrated genetic and epigenetic characterization of a case.

  2018cites this paper
• Fluorescent In Situ Hybridization in Surgical Pathology Practice

  2018cites this paper
• Évolution des oncocytomes rénaux surveillés

  2018cites this paper
• Primary collision tumors of the kidney composed of oncocytoma and papillary renal cell carcinoma: A review.

  2017cites this paper
• Incidental Eosinophilic Chromophobe Renal Cell Carcinoma in Renal Allograft

  2017influential citation
• Pathological nature of renal tumors - does size matter?

  2017influential citation
• Kidney Tumors Associated With Hereditary Cancer Syndromes: An Emerging Opportunity and Responsibility in Surgical Pathology

  2017cites this paper
• Diagnostic accuracy for hybrid oncocytic/chromophobe renal cell tumors by exploiting an immunohistochemical and histochemical combined panel

  2017cites this paper
• Renal hybrid oncocytic/chromophobe tumor associated with multiple schwannomas

  2017influential citation
• Modern Pathologic Diagnosis of Renal Oncocytoma

  2017cites this paper
• Diagnostic criteria for oncocytic renal neoplasms: a survey of urologic pathologists.

  2017cites this paper
• Variants and Variations in Epithelial Renal Cell Tumors in Adults: The Pathologist's Point of View

  2017cites this paper
• Visual evaluation and differentiation of renal oncocytomas from renal cell carcinomas by means of 99mTc-sestamibi SPECT/CT

  2017cites this paper
• Pregled nove SZO-ove histološke klasifikacije epitelnih tumora bubrega

  2016cites this paper
• Computed Tomography Appearance of Renal Hybrid Oncocytic/Chromophobe Tumors

  2016cites this paper
• Glycogen: A must have storage to survive stressful emergencies

  2016cites this paper
• Review of succinate dehydrogenase-deficient renal cell carcinoma with focus on clinical and pathobiological aspects.

  2016cites this paper
• Cystic Renal Oncocytoma and Tubulocystic Renal Cell Carcinoma: Morphologic and Immunohistochemical Comparative Study

  2016cites this paper
• Fluorescent and chromogenic in situ hybridization of CEN17q as a potent useful diagnostic marker for Birt-Hogg-Dubé syndrome-associated chromophobe renal cell carcinomas.

  2016cites this paper
• Molecular genetics and immunohistochemistry characterization of uncommon and recently described renal cell carcinomas.

  2016cites this paper
• Renal oncocytosis: a clinicopathological and cytogenetic study of 42 tumours occurring in 11 patients.

  2016cites this paper
• Recently proposed oncocytic variant of chromophobe renal cell carcinoma ( RCC ) expressing BSND and ATP 6 V 1 G 3 : two new immunohistochemical markers differentiating chromophobe RCC from other RCC subtypes

  2016cites this paper
• Neoplasms of the Kidney

  2016cites this paper
• The Significance of BerEp4 and Cytokeratin 19 Expressions in Epithelial Tumors of Kidney and Renal Pelvis

  2016cites this paper
• Onkozytom versus chromophobes Nierenkarzinom

  2016cites this paper
• Nierentumoren

  2016cites this paper
• Genitourinary System Tumors

  2015cites this paper
• Distal nephron neoplasms.

  2015cites this paper
• Oncocytic-type intraductal papillary mucinous neoplasms: a unique malignant pancreatic tumor with good long-term prognosis.

  2015cites this paper
• Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity.

  2015cites this paper
• FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores

  2015cites this paper
• Immunohistochemical Analysis of Cytochrome c Oxidase Facilitates Differentiation Between Oncocytoma and Chromophobe Renal Cell Carcinoma

  2015cites this paper
• Tumors of the Urinary Tract

  2015cites this paper
• Chromophobe renal cell carcinoma, oncocytic variant: Cytological and ultrastructural observations

  2015cites this paper
• Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt–Hogg–Dubé syndrome

  2015cites this paper
• Review of renal tumors associated with Birt-Hogg-Dubé syndrome with focus on clinical and pathobiological aspects.

  2014cites this paper
• Diagnostic approach to eosinophilic renal neoplasms.

  2014cites this paper