Perinatal outcomes in pregnancies with very and extremely advanced maternal age: An Italian multicenter retrospective cohort study

Oumaima Ammar,Maria Teresa Martini,Sara Lazzarin,A. L. Tramontano,C. Plevani,F. Bonati,V. Seravalli,F. Facchinetti,A. Locatelli,Sara Ornaghi,M. D. Tommaso

Published 2025 in Acta Obstetricia et Gynecologica Scandinavica

ABSTRACT

Pregnancies at very and extremely advanced maternal age (VAMA, 45–49 years and EAMA, ≥50 years) are increasingly common, particularly regarding the influence of assisted reproductive technology (ART), yet their obstetric and perinatal outcomes remain underexplored. This study aimed to investigate maternal and neonatal outcomes in singleton pregnancies among women aged ≥45 years, with a specific focus on ART conception and oocyte source.

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