The Thrombolysis in Myocardial Infarction (TIMI) trial. Phase I findings.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  New England Journal of Medicine

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 4038784
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Echocardiography in the neonate and young infant.

  1985cited by this paper
• Intravenous short-term infusion of streptokinase in acute myocardial infarction.

  1984cited by this paper
• Intravenous streptokinase in evolving acute myocardial infarction.

  1984cited by this paper
• Coronary thrombolysis with intravenously administered human tissue-type plasminogen activator produced by recombinant DNA technology.

  1984cited by this paper
• 1983 Summary: National Hospital Discharge Survey.

  1984cited by this paper
• Coronary thrombolysis with tissue-type plasminogen activator in patients with evolving myocardial infarction.

  1984cited by this paper
• A randomized trial of intravenous and intracoronary streptokinase in patients with acute myocardial infarction.

  1984cited by this paper
• Effects of intracoronary streptokinase and intracoronary nitroglycerin infusion on coronary angiographic patterns and mortality in patients with acute myocardial infarction.

  1984cited by this paper
• Coronary thrombolysis with recombinant human tissue-type plasminogen activator: a prospective, randomized, placebo-controlled trial.

  1984cited by this paper
• Randomized comparison of intravenous versus intracoronary streptokinase for myocardial infarction.

  1984cited by this paper
• Coronary thrombolysis by intravenous streptokinase in acute myocardial infarction: acute and follow-up studies.

  1984cited by this paper
• Intravenous versus intracoronary streptokinase therapy for acute myocardial infarction in community hospitals.

  1984cited by this paper
• Western Washington randomized trial of intracoronary streptokinase in acute myocardial infarction.

  1983cited by this paper
• Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

  1983cited by this paper
• A randomized trial of intracoronary streptokinase in the treatment of acute myocardial infarction.

  1983cited by this paper
• Intracoronary fibrinolytic therapy in acute myocardial infarction. Report of a prospective randomized trial.

  1983cited by this paper
• Systemic thrombolytic therapy of acute myocardial infarction?

  1983cited by this paper
• Prospective randomized trial of intravenous and intracoronary streptokinase in acute myocardial infarction.

  1983cited by this paper
• Effect of intravenous streptokinase on acute myocardial infarction: pooled results from randomized trials.

  1982cited by this paper
• Purification of Human Tissue-Type Plasminogen Activator in Centigram Quantities from Human Melanoma Cell Culture Fluid and Its Conditioning for Use In Vivo

  1982cited by this paper
• Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin.

  1982cited by this paper
• Selective Intracoronary Thrombolysis in Acute Myocardial Infarction and Unstable Angina Pectoris

  1981cited by this paper
• Thrombolysis by human tissue plasminogen activator and urokinase in rabbits with experimental pulmonary embolus

  1981cited by this paper
• The "wavefront phenomenon" of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow.

  1979cited by this paper
• The "wavefront phenomenon" of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow.

  1979cited by this paper
• The Wavefront Phenomenon of Ischemic Cell Death: 1. Myocardial Infarct Size vs Duration of Coronary Occlusion in Dogs

  1977cited by this paper

• Selective Use of Thromboaspiration in STEMI: CMR Evidence Against Routine Practice.

  2026cites this paper
• The thrombectomy in limb ischemia score (TILI-Score): score proposal and results of an interobserver readability survey.

  2026cites this paper
• Drug-coated Balloon Only Percutaneous Coronary Intervention For De-novo Chronic Total Occlusion: Insights From The Multicentre International CTO-DENOVO Registry.

  2026cites this paper
• Intracoronary adrenaline for the treatment of refractory no-reflow phenomenon: A single-centre experience

  2025cites this paper
• Single catheter strategy for transradial angiography and primary percutaneous coronary intervention enhances procedural efficiency, microvascular outcomes, and cost-effectiveness: Implications for STEMI healthcare in resource-limited settings

  2025cites this paper
• Latent Cytomegalovirus Infection Is Associated With Impaired Left Ventricular Function After ST‐Segment–Elevation Myocardial Infarction

  2025cites this paper
• Delayed CPK peak after primary PCI in STEMI: marker of reperfusion quality and short-term outcomes

  2025cites this paper
• Nomogram Predicting In-Hospital Mortality in Patients with Myocardial Infarction Treated with Primary Coronary Interventions Based on Logistic and Angiographic Predictors

  2025cites this paper
• Association between activated clotting time and TIMI flow in STEMI patients pre-treated with unfractionated heparin.

  2025cites this paper
• Limitations of the MIRACLE2 score in coronary cardiac arrest: Findings from a French interventional cohort.

  2025cites this paper
• Linking sequence restoration capability of shuffled coronary angiography to coronary artery disease diagnosis

  2025cites this paper
• High incidence of adverse events in spontaneous coronary artery dissection patients during mid-term follow-up: a persistent challenge ahead.

  2025cites this paper
• A new proposed comprehensive expanded coronary artery lesion description code system and coronary artery angiographic segmental classification – A mathematical model: Indian society of cardiology working group code for physician’s ease

  2025cites this paper
• Fractional Flow Reserve-Guided Complete vs Culprit-Only Revascularization in Non-ST-Elevation Myocardial Infarction and Multivessel Disease: The SLIM Randomized Clinical Trial.

  2025cites this paper
• Age and sex differences in the efficacy of early invasive strategy for non-ST-elevation acute coronary syndrome: A comparative analysis in stable patients

  2025cites this paper
• Poor clinical outcome despite successful recanalisation in patients with acute myocardial infarction undergoing direct percutaneous coronary intervention: a retrospective cohort study

  2025cites this paper
• Impact of different glycoprotein IIb/IIIa inhibitor infusion routes on infarct size and microvascular obstruction in patients with high thrombotic risk ST elevation myocardial infarction

  2025cites this paper
• 40th Anniversary of the TIMI Study Group.

  2025cites this paper
• Smaller infarct size with ticagrelor vs. clopidogrel in STEMI patients: Insights from cardiac magnetic resonance

  2025cites this paper
• Predicting Side Branch Occlusion in Acute Coronary Syndrome Using the Perfusion Balloon

  2025cites this paper
• Association and Prognostic Implications of “No-Reflow Phenomenon” and Hypercoagulability in Patients With ST-Segment Elevation Myocardial Infarction

  2025cites this paper
• Impact of aspiration catheter size on thrombus removal and slow-flow/no-reflow in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.

  2025cites this paper
• Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

  2025cites this paper
• Association between NAFLD and Myocardial Infarct Size in Patients with STEMI: A cross-sectional Study and Bioinformatics Analysis based on the GEO Database

  2025cites this paper
• Surgical versus percutaneous closure of post-infarction ventricular septal rupture; review of literature and single-center experience

  2025cites this paper
• Predictors of ST-Segment Resolution and Its Relationship With Outcomes in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

  2025cites this paper
• Impact of Acute Total Occlusion of the Culprit Vessel on Prognosis and Risk Stratification in Patients with Non-ST-Segment Elevation Myocardial Infarction.

  2025cites this paper
• Genetic Scale for Predicting the No-Reflow Phenomenon in Myocardial Infarction

  2025cites this paper
• The Predictive Value of ALBI Score for No-Reflow in Non-ST Elevation Acute Coronary Syndrome

  2025cites this paper
• Impact of Prior Heart Failure Hospitalization on Long-Term Cardiac Mortality in ST-Elevated Myocardial Infarction Patients.

  2025cites this paper
• Comparison of drug-coated versus conventional balloons for the side branch of the bifurcation lesion - multicenter randomized controlled study - (OCVC-BIF): Design and rationale.

  2025cites this paper
• Awareness for the risk of adverse outcomes of female patients after ST-segment elevation acute coronary syndrome.

  2025cites this paper
• Changes in circulating lipopolysaccharide and zonulin following acute myocardial infarction: The impact of smoking.

  2025cites this paper
• Single centre experience of rotablation-assisted left main percutaneous coronary intervention

  2025cites this paper
• Construction and validation of a personalized risk prediction model for in-hospital mortality in patients with acute myocardial infarction undergoing percutaneous coronary intervention

  2025cites this paper
• Impact of size-dependent differences in excimer laser coronary angioplasty in ST-elevation acute myocardial infarction: nuclear scintigraphy findings

  2025cites this paper
• A chronology of basic and clinical research in the coronary microcirculation.

  2025cites this paper
• Markers in Acute Coronary Syndrome: Distal Coronary Embolism at Percutaneous Coronary Intervention

  2025cites this paper
• Post‐Discharge Major Adverse Events in Patients Surviving Acute Unprotected Left Main Coronary Artery Occlusion

  2025cites this paper
• Angioscopy-Guided Excimer Laser Atherectomy in Femoropopliteal In-Stent Occlusions

  2025cites this paper
• Catheter-Vessel Interactions during Aspiration Thrombectomy: A Comprehensive Analysis Using a Novel Swine Model

  2025cites this paper
• The non-HDL-C/HDL-C ratio is a strong and independent predictor of the no-reflow phenomenon in patients with ST-elevation myocardial infarction

  2024cites this paper
• New scoring balloon to treat moderate-to-severe calcified coronary lesions. The first-in-man Naviscore study

  2024cites this paper
• A Machine Learning Model for the Prediction of No-Reflow Phenomenon in Acute Myocardial Infarction Using the CALLY Index

  2024cites this paper
• Optimized gated a SPECT-derived myocardial salvage index: its prognostic significance in predicting major adverse cardiac events following acute myocardial infarction percussion

  2024cites this paper
• Value of aspartate aminotransferase/alanine aminotransferase Ratio in predicting coronary thrombus burden in ST elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

  2024cites this paper
• Impact of triglyceride-glucose index on intracoronary thrombus burden in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention.

  2024cites this paper
• Pretreatment With Unfractionated Heparin in ST-Elevation Myocardial Infarction—a Propensity Score Matching Analysis.

  2024cites this paper
• Clinical and angiographic characteristics of patients with familial hypercholesterolemia presenting with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

  2024cites this paper
• Association of type-D personality and left-ventricular remodelling in patients treated with primary percutaneous intervention after ST-segment elevation myocardial infarction

  2024cites this paper
• Early coronary revascularization among ‘stable’ patients with non-ST-segment elevation acute coronary syndromes: the role of diabetes and age

  2024cites this paper
• Clinical, laboratory, and procedural predictors of slow flow/no reflow phenomenon after emergency percutaneous coronary interventions in ST-elevated myocardial infarction

  2024cites this paper
• Post-PCI Anticoagulation with Unfractionated Heparin in Acute Coronary Syndrome: Insight from the STOPDAPT-3 Trial.

  2024cites this paper
• Beyond the classic major cardiovascular event outcome for cardiovascular trials.

  2024cites this paper
• Clinical, electrocardiographic, echocardiographic, and angiographic predictors for the final infarct size assessed by cardiac magnetic resonance in acute STEMI patients after primary percutaneous coronary intervention

  2024cites this paper
• The Prognostic Value of the Triglyceride-Glucose Index in Forecasting Ten-Year Major Adverse Cardiovascular Events in Non-Diabetic Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.

  2024cites this paper
• Intravenous antiplatelet therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

  2024cites this paper
• Early unfractionated heparin treatment in patients with STEMI – trial design and rationale

  2024cites this paper
• The effect of the systemic immune–inflammatory index on the no-reflow phenomenon in patients undergoing saphenous vein intervention

  2024cites this paper
• Long-term outcome and prognostic value of angiographic slow/no-reflow phenomenon after emergency percutaneous coronary intervention for ST-elevation myocardial infarction

  2024cites this paper
• Efficacy and safety of intracoronary pro-urokinase combined with low-pressure balloon pre-dilatation during percutaneous coronary intervention in patients with anterior ST-segment elevation myocardial infarction

  2024cites this paper
• The impact of excimer laser coronary angioplasty in acute coronary syndrome due to coronary artery ectasia

  2024cites this paper
• The Comparison of the Initial TIMI Flow Grade in Acute ST-Elevation Myocardial Infarction Patients Receiving Ticagrelor vs. Clopidogrel before Undergoing Primary Percutaneous Coronary Intervention: A Prospective Cohort Study

  2024cites this paper
• In search for “healthy” landing zones for coronary stent placement: are the largest intrasegmental lumens adequate?

  2024cites this paper
• Association of Angiotensin II Receptor Type 1 and Endothelin‐1 Receptor Type A Agonistic Autoantibodies With Adverse Remodeling and Cardiovascular Events After Acute Myocardial Infarction

  2024cites this paper
• Coronary Slow-Flow Phenomenon in Takotsubo Syndrome: The Prevalence, Clinical Determinants, and Long-Term Prognostic Impact

  2024cites this paper
• Use of the Indigo CAT RX aspiration system during percutaneous coronary intervention

  2024cites this paper
• Fibrinolytic Agents in Thromboembolic Diseases: Historical Perspectives and Approved Indications

  2024cites this paper
• IV Thrombolysis in Basilar Artery Occlusion: Outcomes and Comparison With Endovascular Thrombectomy.

  2024cites this paper
• Twelve‐year trends in unprotected left main coronary artery occlusion: insights from a real‐world multicentre study

  2024cites this paper
• Basic Overview of Conventional Coronary Angiography for Planning Cardiac Surgery

  2024cites this paper
• Cross‐Sectional Imaging Modalities in Correlation to the Thrombolysis in Cerebral Infarction Score: The Next Frontier in Adjunctive Endovascular Stroke Therapy

  2024cites this paper
• Clinical Impact of Perfusion Balloon for ST-segment Elevated Myocardial Infarction: RYUSEI Study.

  2024cites this paper
• Incidencia de eventos cardiovasculares mayores intrahospitalarios en pacientes sometidos a tromboaspiración mecánica más IIb/IIIa contra solo inhibidores de la glucoproteína IIb/IIIa en infarto agudo al miocardio con elevación del segmento ST

  2024cites this paper
• Predictors of Optical Coherence Tomography-Defined Calcified Nodules in Patients With Acute Coronary Syndrome　- A Substudy From the TACTICS Registry.

  2024cites this paper
• Increased [18F]FDG uptake in the infarcted myocardial area displayed by combined PET/CMR correlates with snRNA-seq-detected inflammatory cell invasion

  2024cites this paper
• Aortic Arch Calcification in Predicting Unfavorable Angiographic Outcomes for Patients with ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

  2024cites this paper
• One-Month Dual Antiplatelet Therapy in High Bleeding Risk Asian Patients Undergoing Percutaneous Coronary Intervention　― Onyx ONE Clear 2-Year Results ―

  2024cites this paper
• Angiographic characteristics of Patients with STEMI and COVID-19 - Insights from NACMI Registry.

  2024cites this paper
• Visual Estimates of Coronary Slow Flow Are Not Associated With Invasive Wire-Based Diagnoses of Coronary Microvascular Dysfunction

  2024cites this paper
• Impact of the fibrosis-4 index in patients with ST-elevated myocardial infarction

  2024cites this paper
• New-generation single-layer PTFE-covered coronary stent for endovascular repair of iatrogenic arterial side-branch injury in non-coronary lesions for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators.

  2024cites this paper
• Changes of coronary blood flow before and after post-dilation following primary percutaneous coronary intervention in patients with STEMI

  2024cites this paper
• Predictors of No-reflow Phenomenon Development in Patients Presenting with ST Segment Elevated Myocardial Infarction and Treated with Primary Percutaneous Coronary Intervention

  2023cites this paper
• Intracoronary thrombus assessment with cardiac computed tomography angiography in a deferred stenting strategy: the MATURE prospective study (MSCT to Assess ThrombUs REsolution)

  2023cites this paper
• Acute Heart Failure and Coronary Blood Flow in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: An Observational Cohort Study

  2023cites this paper
• Chinese expert consensus on the diagnosis and treatment of coronary microvascular diseases (2023 Edition)

  2023cites this paper
• A retrospective study: Associationof C-reactive protein and uric acid to albumin ratio with the no-reflow phenomenonin patients with ST elevation myocardial infarction.

  2023cites this paper
• Subtle Changes in Myocardial Work Indices Assessed by 2D-Speckle Tracking Echocardiography Are Linked with Pathological LV Remodeling and MACEs Following an Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention

  2023cites this paper
• Microvascular Dysfunction in COVID-19 Patients with Acute Coronary Syndrome

  2023cites this paper
• Canada acute coronary syndrome risk score predicts no-/slow-reflow in ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

  2023cites this paper
• Procedural and one-year outcomes following drug-eluting stent and drug-coated balloon combination for the treatment of de novo diffuse coronary artery disease: the HYPER Study.

  2023cites this paper
• The results of the use of thrombolytic therapy in acute myocardial infarction at the prehospital and hospital stage

  2023cites this paper
• The Relationship Between TIMI Flow and MAPH Score in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI.

  2023cites this paper
• Deep Learning-based Prediction of Percutaneous Recanalization in Chronic Total Occlusion Using Coronary CT Angiography.

  2023cites this paper
• Post-procedural and long-term functional outcomes of jailed side branches in stented coronary bifurcation lesions assessed with side branch Murray law–based quantitative flow ratio

  2023cites this paper
• Efficacy and safety of different dual antiplatelet strategies in patients undergoing percutaneous coronary intervention: A systematic review and network meta‐analysis

  2023cites this paper
• Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction Patients After Percutaneous Coronary Intervention: Influencing Factors and Intervention Strategies

  2023cites this paper
• Prognostic value and clinical usefulness of PIANO score in patients undergoing primary percutaneous coronary intervention.

  2023cites this paper
• Red Cell Distribution Width and Neutrophil-Lymphocyte Ratio Predict Thrombus Burden in Acute Myocardial Infarction

  2023cites this paper