Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Molecular and Cellular Endocrinology

• Publication date

  2001-07-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0303-7207(01)00539-1PMID 11476939
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Localization and Insulin-regulated Relocation of Phosphoinositide 5-Kinase PIKfyve in 3T3-L1 Adipocytes*

  2001cited by this paper
• Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases

  2000cited by this paper
• PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.

  2000cited by this paper
• Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110alpha and p110beta catalytic subunits of class-Ia phosphoinositide 3-kinases.

  2000cited by this paper
• Phosphatidylinositol Phosphate Kinases, a Multifaceted Family of Signaling Enzymes*

  1999cited by this paper
• Molecular Basis of Insulin-stimulated GLUT4 Vesicle Trafficking

  1999cited by this paper
• The Identification of Phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and Its Regulation by Interleukin-2*

  1999cited by this paper
• PIKfyve, a Mammalian Ortholog of Yeast Fab1p Lipid Kinase, Synthesizes 5-Phosphoinositides

  1999cited by this paper
• Complementation Analysis in PtdInsPKinase-deficient Yeast Mutants Demonstrates ThatSchizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5-Kinases*

  1999cited by this paper
• Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance.

  1999cited by this paper
• Phosphoinositide 3-Kinases and Their FYVE Domain-containing Effectors as Regulators of Vacuolar/Lysosomal Membrane Trafficking Pathways*

  1999cited by this paper
• Signaling Pathways Mediating Insulin‐Stimulated Glucose Transport

  1999cited by this paper
• Insulin Activates the α Isoform of Class II Phosphoinositide 3-Kinase*

  1999cited by this paper
• Signaling by distinct classes of phosphoinositide 3-kinases.

  1999cited by this paper
• Signaling Mechanisms That Regulate Glucose Transport*

  1999cited by this paper
• Cloning, Characterization, and Expression of a Novel Zn2+-Binding FYVE Finger-Containing Phosphoinositide Kinase in Insulin-Sensitive Cells

  1999cited by this paper
• Phosphoinositide kinases.

  1998cited by this paper
• Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling.

  1998cited by this paper
• Fab1p Is Essential for PtdIns(3)P 5-Kinase Activity and the Maintenance of Vacuolar Size and Membrane Homeostasis

  1998cited by this paper
• Intracellular Localization of Phosphatidylinositide 3-kinase and Insulin Receptor Substrate-1 in Adipocytes: Potential Involvement of a Membrane Skeleton

  1998cited by this paper
• Dynamics of Insulin Signaling in 3T3-L1 Adipocytes

  1998cited by this paper
• Platelet-derived Growth Factor Inhibits Insulin Stimulation of Insulin Receptor Substrate-1-associated Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes without Affecting Glucose Transport*

  1998cited by this paper
• Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body.

  1998cited by this paper
• Stimulation of IRS-1-associated Phosphatidylinositol 3-Kinase and Akt/Protein Kinase B but Not Glucose Transport by β1-Integrin Signaling in Rat Adipocytes*

  1998cited by this paper
• Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts.

  1997cited by this paper
• A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

  1997cited by this paper
• Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis

  1997cited by this paper
• Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes

  1997cited by this paper
• Insulin signal transduction and the IRS proteins.

  1996cited by this paper
• YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites

  1996cited by this paper
• Insulin-mediated Targeting of Phosphatidylinositol 3-Kinase to GLUT4-containing Vesicles (*)

  1996cited by this paper
• Binding to the Platelet-derived Growth Factor Receptor Transiently Activates the p85α-p110α Phosphoinositide 3-Kinase Complex in Vivo*

  1996cited by this paper
• Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation.

  1996cited by this paper
• Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.

  1996cited by this paper
• Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes.

  1996cited by this paper
• Two Naturally Occurring Mutant Insulin Receptors Phosphorylate Insulin Receptor Substrate-1 (IRS-1) but Fail to Mediate the Biological Effects of Insulin

  1996cited by this paper
• The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake.

  1995cited by this paper
• Activation of Mitogen-activated Protein Kinase and Phosphatidylinositol 3′-Kinase Is Not Sufficient for the Hormonal Stimulation of Glucose Uptake, Lipogenesis, or Glycogen Synthesis in 3T3-L1 Adipocytes (*)

  1995cited by this paper
• A human phosphatidylinositol 3‐kinase complex related to the yeast Vps34p‐Vps15p protein sorting system.

  1995cited by this paper
• Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast.

  1995cited by this paper
• Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.

  1994cited by this paper
• Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes.

  1994cited by this paper
• Insulin-induced activation of phosphatidyl inositol 3-kinase. Demonstration that the p85 subunit binds directly to the COOH terminus of the insulin receptor in intact cells.

  1994cited by this paper
• Regulation by insulin of phosphatidylinositol 3'-kinase bound to alpha- and beta-isoforms of p85 regulatory subunit.

  1994cited by this paper
• A dynamic system for suppression and re-expression of insulin and pervanadate bioresponses in rat adipocytes. Treatment with okadaic acid and staurosporine.

  1994cited by this paper
• Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle

  1994cited by this paper
• Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase.

  1993cited by this paper

• PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation

  2018cites this paper
• Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity

  2017cites this paper
• Rôle du Ptdlns5P et de PIKfyve dans le contrôle de l'intégrité des granules plaquettaires

  2016cites this paper
• Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.

  2015cites this paper
• Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve‐dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012)

  2015cites this paper
• Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching.

  2013cites this paper
• Myotubularin phosphoinositide phosphatases in human diseases.

  2012cites this paper
• PIKfyve and its Lipid products in health and in sickness.

  2012cites this paper
• The Nucleophosmin-Anaplastic Lymphoma Kinase Oncogene Interacts, Activates, and Uses the Kinase PIKfyve to Increase Invasiveness*

  2011cites this paper
• ArPIKfyve Regulates Sac3 Protein Abundance and Turnover

  2010cites this paper
• YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.

  2009cites this paper
• Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin*

  2009cites this paper
• Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.

  2008cites this paper
• Elevated levels of PtdIns5P in NPM-ALK transformed cells: implication of PIKfyve.

  2008cites this paper
• PIKfyve: Partners, significance, debates and paradoxes

  2008cites this paper
• The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans.

  2006cites this paper
• A study of the regulation and function of Fab1p, a phosphatidylinositol 3-phosphate 5 kinase in Saccharomyces cerevisiae

  2005cites this paper
• Physiological role of Vps34 phosphatidylinositol 3-kinase in mammalian cells.

  2005cites this paper
• A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity

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• Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation.

  2004cites this paper
• PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis.

  2003cites this paper
• Identification of Mammalian Vps24p as an Effector of Phosphatidylinositol 3,5-Bisphosphate-dependent Endosome Compartmentalization*

  2003cites this paper
• Regulating Glut4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases.

  2003cites this paper
• Measurements of cellular phosphoinositide levels in 3T3-L1 adipocytes.

  2003cites this paper
• Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.

  2002cites this paper
• PIKfyve: The road to PtdIns 5‐P and PtdIns 3,5‐P2

  2001cites this paper
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