Further studies on the pathway of serine formation from carbohydrate.

In a previous paper (1) the authors reported on the enzymatic formation of serine from glyceric acid (GA), 3-phosphoglyceric acid (PGA), and 3-phosphohydroxypyruvic acid (PHPA).’ It was also suggested that the biosynthesis of serine might involve the following enzyme activities: a kinase phosphorylating GA, a dehydrogenase acting on PGA, a transaminase aminating PHPA, and the dephosphorylation of phosphoserine by phosphatase. It was not proved, however, in the previous work that phosphoserine was an obligatory intermediate in the reaction sequence between GA or PGA and serine. This evidence is now provided, and the results of further studies on the nature of the different steps of the above reaction sequence are reported.

• Publication year

  1957

• Venue

  Journal of Biological Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/s0021-9258(18)65032-xPMID 13398409
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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