An overhanging 3' terminus is a conserved feature of telomeres

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Molecular and Cellular Biology

• Publication date

  1989-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.9.1.345-348.1989PMID 2927395PMCID PMC362181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Generation of telomere-length heterogeneity in Saccharomyces cerevisiae.

  1988cited by this paper
• Identification of the telomeric sequence of the acellular slime molds Didymium iridis and Physarum polycephalum.

  1987cited by this paper
• Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs.

  1987cited by this paper
• Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.

  1987cited by this paper
• S1 nuclease sensitivity of a double-stranded telomeric DNA sequence.

  1987cited by this paper
• Dynamics of telomere length variation in Tetrahymena thermophila.

  1987cited by this paper
• The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity.

  1987cited by this paper
• Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA.

  1986cited by this paper
• Structure of an adenine˙cytosine base pair in DNA and its implications for mismatch repair

  1986cited by this paper
• Identification of a telomere-binding activity from yeast.

  1986cited by this paper
• Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.

  1985cited by this paper
• Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex.

  1984cited by this paper
• The molecular structure of centromeres and telomeres.

  1984cited by this paper
• DNA termini in ciliate macronuclei.

  1983cited by this paper
• Growth of chromosome ends in multiplying trypanosomes

  1983cited by this paper
• The terminal organization of macronuclear DNA in Oxytricha fallax.

  1982cited by this paper
• All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3' terminus.

  1981cited by this paper
• Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena.

  1981cited by this paper
• Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo.

  1980cited by this paper
• Sequencing end-labeled DNA with base-specific chemical cleavages.

  1980cited by this paper
• Base-specific reactions useful for DNA sequencing: methylene blue--sensitized photooxidation of guanine and osmium tetraoxide modification of thymine.

  1978cited by this paper
• A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena.

  1978cited by this paper
• Origin of concatemeric T7 DNA.

  1972cited by this paper
• TRANSITIONS OF DNA HOMOPOLYMERS.

  1964cited by this paper
• Base-specific reactions useful for DNA sequencing: methylene blue - sensitized photooxidation of guanine and osmium tetraoxide modification of thymine

  year unknowncited by this paper

• Telomere 3’-overhang attrition and persistent telomeric DNA damage response in failing human hearts

  2025cites this paper
• Chromosomal Instability and Telomere Attrition in Systemic Sclerosis: A Historical Perspective

  2025cites this paper
• Noncanonical chromosomal-end-specific telomeric arrays in naturally telomerase-negative yeasts

  2025cites this paper
• In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function.

  2025cites this paper
• End resection and telomere healing of DNA double-strand breaks during nematode programmed DNA elimination

  2024cites this paper
• End resection and telomere healing of DNA double-strand breaks during nematode programmed DNA elimination

  2024cites this paper
• Methods that shaped telomerase research

  2023cites this paper
• Telomere and Telomerase-Associated Proteins in Endometrial Carcinogenesis and Cancer-Associated Survival

  2022cites this paper
• The Nematode Oscheius tipulae as A Genetic Model for Programmed DNA Elimination

  2022cites this paper
• Telomeres and Their Neighbors

  2022cites this paper
• Regulation of Antigenic Variation by Trypanosoma brucei Telomere Proteins Depends on Their Unique DNA Binding Activities

  2021cites this paper
• Exploring TERRA during Leishmania major developmental cycle and continuous in vitro passages.

  2021cites this paper
• The effects of anabolic-androgenic steroids on aging in bodybuilders

  2020cites this paper
• Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms

  2020cites this paper
• Role of folding kinetics of secondary structures in telomeric G-overhangs in the regulation of telomere maintenance in Saccharomyces cerevisiae

  2020cites this paper
• G-Quadruplexes at Telomeres: Friend or Foe?

  2020cites this paper
• Genome (in)stability at tandem repeats.

  2020cites this paper
• Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms

  2019cites this paper
• Telomere dynamics in adult hematological malignancies.

  2019cites this paper
• TERT gene: its function and dysregulation in cancer

  2019cites this paper
• Stretching, scrambling, piercing and entangling: Challenges for telomeres in mitotic and meiotic chromosome segregation.

  2018cites this paper
• Telomeres, Telomerase and Ageing.

  2018cites this paper
• Alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.

  2018cites this paper
• The Role of RAD4 in DNA Repair and Its Interplay with Telomeres in Tetrahymena thermophila

  2018cites this paper
• Trypanosoma brucei UMSBP2 is a single-stranded telomeric DNA binding protein essential for chromosome end protection

  2018cites this paper
• Biochemical and structural analysis of shelterin subcomplexes

  2018cites this paper
• The telomeric DNA damage response: Insights into telomere compaction and identification of novel damage signaling factors

  2018cites this paper
• Functional dissection of breast cancer risk-associated TERT promoter variants

  2017cites this paper
• Telomere maintenance in soft tissue sarcomas

  2017cites this paper
• The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1

  2017cites this paper
• Regulation of telomere metabolism by the RNA processing protein Xrn1

  2017cites this paper
• Thermodynamic Analyses of G-Quadruplexes Formed by DNA Molecules Containing Four Repeats of the Human Telomeric Sequence

  2017cites this paper
• Current Insights to Regulation and Role of Telomerase in Human Diseases

  2017cites this paper
• Guarding chromosomes from oxidative DNA damage to the very end.

  2016cites this paper
• The role of telomere damage in cardiomyocyte ageing

  2016cites this paper
• Effects of initial telomere length distribution on senescence onset and heterogeneity

  2016cites this paper
• Molecular docking of the anticancer bioactive compound proceraside with macromolecules involved in the cell cycle and DNA replication.

  2016cites this paper
• A Thermodynamic Study of Adenine and Thymine Substitutions in the Loops of the Oligodeoxyribonucleotide HTel.

  2016cites this paper
• G-Quadruplex ligands: Potent inhibitors of telomerase activity and cell proliferation in Plasmodium falciparum.

  2016cites this paper
• Target fishing of glycopentalone using integrated inverse docking and reverse pharmacophore mapping approach.

  2016cites this paper
• The Role of Telomere Maintenance in Adult Mammalian Acute Central Nervous System Injury and Retinal Ganglion Cell Apoptosis

  2016cites this paper
• Telomere length as a putative biomarker of health and disease

  2016cites this paper
• Mechanisms of the Human Telomerase Catalytic Cycle

  2016cites this paper
• PfGBP: una proteína de unión al telómero de Plasmodium falciparum PfGBP: A Plasmodium falciparum telomere binding protein PfGBP: uma proteína de ligação o telômero em Plasmodium falciparum

  2016cites this paper
• Relationships between nuclear lamins and telomere biology in progeroid laminopathies and cancer

  2015cites this paper
• ANALYSIS OF THE ROLE OF TRF1 PHOSPHORYLATION AND TRF1 DOMAIN STRUCTURE IN ALTERNATIVE LENGTHENING OF TELOMERES ACTIVITY

  2015cites this paper
• Rôle du stress oxydant et des cassures de l’ADN dans l’émergence néoplasique post-sénescence

  2015cites this paper
• TELOMERASE ACTIVATION AND ITS CLINICAL IMPLICATIONS IN HUMAN THYROID TUMORS

  2015cites this paper
• Characterization of the Arabidopsis Telomerase Negative Regulator: A TE-Containing lncRNA TER2- Defining Its Role in and beyond Telomere Biology

  2015cites this paper
• ROLE OF TELOMERES IN CAUSING CANCER AND TARGETING TELOMERASE IN TREATMENT OF CANCER AS BETTER THAN CONVENTIONAL THERAPY

  2015cites this paper
• Functional analysis of candidate phosphorylation sites of telomere repeat binding factor 2 (TRF2)

  2015cites this paper
• Interaction of polycationic Ni(II)-salophen complexes with G-quadruplex DNA.

  2014cites this paper
• Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.

  2014cites this paper
• Elucidation of the DNA end-replication problem in Saccharomyces cerevisiae.

  2014cites this paper
• SURVEY AND SUMMARY G-quadruplexes in viruses: function and potential therapeutic applications

  2014cites this paper
• Telomere and telomerase biology.

  2014cites this paper
• Telomere and Proximal Sequence Analysis Using High-Throughput Sequencing Reads

  2014cites this paper
• Programmed Genome Processing in Ciliates

  2014cites this paper
• Arrangements of human telomere DNA quadruplex in physiologically relevant K+ solutions

  2014cites this paper
• Development of Cancer Therapeutics and Diagnostics Targeting Telomere and Telomerase

  2014cites this paper
• Molecular Recognition in Complexes of TRF Proteins with Telomeric DNA

  2014cites this paper
• G-quadruplexes in viruses: function and potential therapeutic applications

  2014cites this paper
• One Identity or More for Telomeres?

  2013cites this paper
• Telomere Shortening Mechanisms

  2013cites this paper
• TERF 1 – telomeric repeat-binding factor 1 ; TRF 2 or TERF 2 – telomeric repeat-binding factor 2 Mini review TELOMERASE AND ITS EXTRACURRICULAR ACTIVITIES

  2013cites this paper
• Telomere-end processing: mechanisms and regulation

  2013influential citation
• Telomerase and its extracurricular activities

  2013cites this paper
• The sequence specificity of the anti-tumour drug, cisplatin, in telomeric DNA sequences compared with consecutive guanine DNA sequences.

  2012cites this paper
• The Telomerase Complex: An Overview

  2012cites this paper
• Telomery i telomeraza w komórkach roślinnych

  2012cites this paper
• The role of shelterin in maintaining telomere integrity.

  2012cites this paper
• Nanochannels: biological channel analogues.

  2012cites this paper
• Blunt-ended telomeres: an alternative ending to the replication and end protection stories.

  2012cites this paper
• Telomere resolution and genomic instability in mouse embryonic stem cells

  2012cites this paper
• The role of the pentose phosphate pathway in TMPyP4 resistance and the telomere uncapping response

  2012cites this paper
• Telomere end processing: unexpected complexity at the end game.

  2012cites this paper
• DNA Damage Response/Signaling and Genome (In)Stability as the New Reliable Biological Parameters Defining Clinical Feature of CLL

  2012cites this paper
• Beads-on-a-string structure of long telomeric DNAs under molecular crowding conditions.

  2012cites this paper
• RELATIONSHIPS BETWEEN TELOMERIC SEQUENCES AND STRUCTURES, DNA REPLICATION, AND THE FUNCTION OF THE WERNER SYNDROME PROTEIN

  2012cites this paper
• Telomerase Regulation in Arabidopsis thaliana

  2012cites this paper
• Cellular Senescence, Telomerase, and Cancer in Human Cells

  2012cites this paper
• BIOGENESIS OF TELOMERASE RNA IN FISSION YEAST

  2012cites this paper
• Targeted cloning of fungal telomeres.

  2011cites this paper
• QTL Mapping and Candidate Gene Analysis of Telomere Length Control Factors in Maize (Zea mays L.)

  2011cites this paper
• Role of telomere dysfunction in genetic intratumor diversity.

  2011cites this paper
• The sequence selectivity of DNA-targeted 9-aminoacridine cisplatin analogues in a telomere-containing DNA sequence

  2011cites this paper
• Studies of the mechanism of recombinational telomere elongation in an alternative lengthening of telomere (ALT)-like Kluyveromyces lactis stn1-M1 mutant

  2011cites this paper
• Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells.

  2010cites this paper
• Mechanisms and regulation of DNA end resection

  2010influential citation
• C-terminal amino acids 290-328 of LPTS/PinX1 confer telomerase inhibition.

  2010cites this paper
• Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments.

  2010cites this paper
• A sequence-dependent exonuclease activity from Tetrahymena thermophila

  2010cites this paper
• Embryonic Stem Cells: Prospects of Regenerative Medicine for the Treatment of Human Aging

  2010cites this paper
• Telomerase and Alternative Lengthening of Telomeres

  2009cites this paper
• DNA end resection: many nucleases make light work.

  2009cites this paper
• Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation

  2009cites this paper
• Characterization of homologous recombination proteins in telomere processing and t-circle formation

  2009cites this paper
• Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.

  2009cites this paper
• JCB_200812121 827..840

  2009cites this paper
• Arrangements of human telomere DNA quadruplex in physiologically relevant K+ solutions

  2009cites this paper