Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton

Rictor, a component of mammalian target of rapamycin complex 2 (mTORC2), controls neutrophil chemotaxis by regulating the dynamics of the actin cytoskeleton via Rac and Cdc42. This function of Rictor is independent of mTORC2 and the kinase activity of mTOR.

• Publication year

  2013

• Venue

  Molecular Biology of the Cell

• Publication date

  2013-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E13-07-0405PMID 24006489PMCID 3814157
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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