Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Gut

• Publication date

  2005-06-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1136/gut.2004.057968PMID 15951547PMCID PMC1774606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• EDITOR’S QUIZ: GI SNAPSHOT

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  2003influential reference
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  2003cited by this paper
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